DACH1 | Proteintech Group 10914-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

DACH1

catalog :

10914-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 29

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1b	Lyons S, Achorn C, Kedersha N, Anderson P, Ivanov P. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016;44:6949-60 pubmed publisher
	Hu X, Zhang L, Li Y, Ma X, Dai W, Gao X, et al. Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling. EBioMedicine. 2020;56:102800 pubmed publisher
	Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, et al. Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool. Stem Cell Reports. 2019;12:135-151 pubmed publisher
	Lu G, Geng F, Xiao Z, Chen Y, Han Y, You C, et al. MicroRNA-6807-3p promotes the tumorigenesis of glioma by targeting downstream DACH1. Brain Res. 2019;1708:47-57 pubmed publisher
	Okabe M, Motojima M, Miyazaki Y, Pastan I, Yokoo T, Matsusaka T. Global polysome analysis of normal and injured podocytes. Am J Physiol Renal Physiol. 2019;316:F241-F252 pubmed publisher
	Bonet F, Pereira P, Bover O, Marques S, Inácio J, Belo J. CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart. Dev Dyn. 2018;247:1135-1145 pubmed publisher
	Su T, Stanley G, Sinha R, D Amato G, Das S, Rhee S, et al. Single-cell analysis of early progenitor cells that build coronary arteries. Nature. 2018;559:356-362 pubmed publisher
	Qin G, Lian J, Huang L, Zhao Q, Liu S, Zhang Z, et al. Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis. Oncoimmunology. 2018;7:e1442167 pubmed publisher
	Mendes L, Castilho A, Pinho C, Gonçalvez B, Razza E, Chuffa L, et al. Modulation of inflammatory and hormonal parameters in response to testosterone therapy: Effects on the ventral prostate of adult rats. Cell Biol Int. 2018;42:1200-1211 pubmed publisher
	Liu Q, Li A, Yu S, Qin S, Han N, Pestell R, et al. DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis. J Hematol Oncol. 2018;11:53 pubmed publisher
	Poppe D, Doerr J, Schneider M, Wilkens R, Steinbeck J, Ladewig J, et al. Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity. Stem Cells Transl Med. 2018;7:477-486 pubmed publisher
	Cui Q, Kong D, Li Z, Ahiable P, Wang K, Wu K, et al. Dachshund 1 is Differentially Expressed Between Male and Female Breast Cancer: A Matched Case-Control Study of Clinical Characteristics and Prognosis. Clin Breast Cancer. 2018;18:e875-e882 pubmed publisher
	Rhee S, Chung J, King D, D Amato G, Paik D, Duan A, et al. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nat Commun. 2018;9:368 pubmed publisher
	Doran A, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond C, et al. CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis. J Clin Invest. 2017;127:4075-4089 pubmed publisher
	Sharma B, Ho L, Ford G, Chen H, Goldstone A, Woo Y, et al. Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Dev Cell. 2017;42:655-666.e3 pubmed publisher
	Chang A, Raftrey B, D Amato G, Surya V, Poduri A, Chen H, et al. DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017;31:1308-1324 pubmed publisher
	Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell R, et al. DACH1 suppresses breast cancer as a negative regulator of CD44. Sci Rep. 2017;7:4361 pubmed publisher
	Yackle K, Schwarz L, Kam K, Sorokin J, Huguenard J, Feldman J, et al. Breathing control center neurons that promote arousal in mice. Science. 2017;355:1411-1415 pubmed publisher
	Lorenz C, Lesimple P, Bukowiecki R, Zink A, Inak G, Mlody B, et al. Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell. 2017;20:659-674.e9 pubmed publisher
	Liu Q, Zhou Y, Liu H, Qiu W, Liu H, Hu T, et al. Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity. Oncotarget. 2016;7:86547-86560 pubmed publisher
	Bu X, Qiu C, Wang C, Jiang Z. Inhibition of DACH1 activity by short hairpin RNA represses cell proliferation and tumor invasion in pancreatic cancer. Oncol Rep. 2016;36:745-54 pubmed publisher
	Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, et al. Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions. Neurosci Res. 2016;110:18-28 pubmed publisher
	Ben Halima S, Mishra S, Raja K, Willem M, Baici A, Simons K, et al. Specific Inhibition of Î²-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. Cell Rep. 2016;14:2127-2141 pubmed publisher
	Bung R, WÃ¶rsdÃ¶rfer P, Thier M, Lemke K, Gebhardt M, Edenhofer F. Partial Dedifferentiation of Murine Radial Glia-Type Neural Stem Cells by Brn2 and c-Myc Yields Early Neuroepithelial Progenitors. J Mol Biol. 2016;428:1476-83 pubmed publisher
	Liu Y, Zhou R, Yuan X, Han N, Zhou S, Xu H, et al. DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/Î²-catenin signaling. Oncotarget. 2015;6:8621-34 pubmed
	Maneix L, Antonson P, Humire P, Rochel Maia S, CastaÃ±eda J, Omoto Y, et al. Estrogen receptor Î² exon 3-deleted mouse: The importance of non-ERE pathways in ERÎ² signaling. Proc Natl Acad Sci U S A. 2015;112:5135-40 pubmed publisher
	Han N, Yuan X, Wu H, Xu H, Chu Q, Guo M, et al. DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling. Oncotarget. 2015;6:5877-88 pubmed
	Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, et al. The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module. Cancer Res. 2015;75:1992-2004 pubmed publisher
	Mendes L, Scarano W, Rochel Maia S, Fioruci Fontaneli B, Chuffa L, Anselmo Franci J, et al. Androgen therapy reverses injuries caused by ethanol consumption in the prostate: testosterone as a possible target to ethanol-related disorders. Life Sci. 2015;120:22-30 pubmed publisher

product information

CatalogNo :

10914-1-AP

AntigenName :

DACH1

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

dachshund homolog 1 (Drosophila)

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, ChIP, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

DACH, DACH1, Dachshund homolog 1, Dachshund-1

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC021219

Category :

Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:15000 ;