| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 5c
| Lin X, Zhan J, Zhong J, Wang Y, Wang Y, Li S, et al. lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. Aging (Albany NY). 2019;11:523-535 pubmed publisher |
- western blot; mouse; loading ...; fig 1a
| Guo Y, Li H, Ke X, Deng M, Wu Z, Cai Y, et al. Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging. Mol Neurobiol. 2019;56:3368-3379 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 5q
| Hamada S, Shimosegawa T, Taguchi K, Nabeshima T, Yamamoto M, Masamune A. Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma. Am J Physiol Gastrointest Liver Physiol. 2018;314:G65-G74 pubmed publisher |
- western blot; human; 1:100; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher |
- western blot; human; fig 8
| Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, et al. HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. J Biol Chem. 2016;291:12688-705 pubmed publisher |
- western blot; human; fig s2
| Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 3
| Vermeer D, Coppock J, Zeng E, Lee K, Spanos W, Onken M, et al. Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis. Oncotarget. 2016;7:24194-207 pubmed publisher |
- western blot; mouse; fig 5
- western blot; human; fig 7
| Chung S, Moon H, Ju H, Kim D, Cho K, Ribback S, et al. Comparison of liver oncogenic potential among human RAS isoforms. Oncotarget. 2016;7:7354-66 pubmed publisher |
| Wang X, Li D, Wu H, Liu F, Liu F, Zhang Q, et al. LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding. Mech Ageing Dev. 2020;190:111293 pubmed publisher |
| Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, et al. Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription. Theranostics. 2020;10:6839-6853 pubmed publisher |
| Honda Y, Huang A, Tanaka T, Han X, Gao B, Liu H, et al. Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics. Int J Mol Sci. 2020;21: pubmed publisher |
| Jia Y, Jin H, Gao L, Yang X, Wang F, Ding H, et al. A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. J Cell Mol Med. 2020;24:5304-5316 pubmed publisher |
| Sethi N, Kikuchi O, Duronio G, Stachler M, McFarland J, Ferrer Luna R, et al. Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model. Nat Genet. 2020;52:219-230 pubmed publisher |
| Feng X, Pan J, Li J, Zeng C, Qi W, Shao Y, et al. Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR. Aging (Albany NY). 2020;12:1087-1103 pubmed publisher |
| Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, et al. Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function. Aging (Albany NY). 2020;12:650-671 pubmed publisher |
| Dang Y, An Y, He J, Huang B, Zhu J, Gao M, et al. Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression. Aging Cell. 2020;19:e13060 pubmed publisher |
| Göbl C, Morris V, van Dam L, Visscher M, Polderman P, Hartlmüller C, et al. Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A. Redox Biol. 2020;28:101316 pubmed publisher |
| Guo S, Jian L, Tao K, Chen C, Yu H, Liu S. Novel Breast-Specific Long Non-coding RNA LINC00993 Acts as a Tumor Suppressor in Triple-Negative Breast Cancer. Front Oncol. 2019;9:1325 pubmed publisher |
| Liu F, Shi J, Zhang Y, Lian A, Han X, Zuo K, et al. NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling. Oxid Med Cell Longev. 2019;2019:4286213 pubmed publisher |
| Zhao J, Honda Y, Tanaka T, Hashimoto Y, Matsumoto N. Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria. Materials (Basel). 2019;13: pubmed publisher |
| Li Y, Li X, Cao M, Jiang Y, Yan J, Liu Z, et al. Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. Signal Transduct Target Ther. 2019;4:50 pubmed publisher |
| Wen S, Cheng S, Ng S, Aneja R, Chen C, Huang C, et al. Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells. Int J Mol Med. 2019;44:2123-2132 pubmed publisher |
| Malaise O, Tachikart Y, Constantinides M, Mumme M, Ferreira Lopez R, Noack S, et al. Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development. Aging (Albany NY). 2019;11:9128-9146 pubmed publisher |
| Li T, Xiong Y, Wang Q, Chen F, Zeng Y, Yu X, et al. Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway. Artif Cells Nanomed Biotechnol. 2019;47:4001-4011 pubmed publisher |
| Xin M, Jin X, Cui X, Jin C, Piao L, Wan Y, et al. Dipeptidyl peptidase-4 inhibition prevents vascular aging in mice under chronic stress: Modulation of oxidative stress and inflammation. Chem Biol Interact. 2019;314:108842 pubmed publisher |
| Saxena S, Vekaria H, Sullivan P, Seifert A. Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence. Nat Commun. 2019;10:4400 pubmed publisher |
| Tian S, Feng J, Cao Y, Shen S, Cai Y, Yang D, et al. Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications. Life Sci Alliance. 2019;2: pubmed publisher |
| Rana T, Jiang C, Liu G, Miyata T, Antony V, Thannickal V, et al. PAI-1 Regulation of TGF-β1-induced ATII Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages. Am J Respir Cell Mol Biol. 2019;: pubmed publisher |
| Fan X, Bjerke G, Riemondy K, Wang L, Yi R. A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model. Mol Carcinog. 2019;58:2241-2253 pubmed publisher |
| Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, et al. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis. Stem Cell Res Ther. 2019;10:268 pubmed publisher |
| Wang S, Kim J, Lee C, Oh D, Han J, Kim T, et al. Tumor necrosis factor-inducible gene 6 reprograms hepatic stellate cells into stem-like cells, which ameliorates liver damage in mouse. Biomaterials. 2019;219:119375 pubmed publisher |
| Ghanam A, Cao J, Ouyang X, Song X. New Insights into Chronological Mobility of Retrotransposons In Vivo. Oxid Med Cell Longev. 2019;2019:2818415 pubmed publisher |
| Li Y, Kong R, Chen H, Zhao Z, Li L, Li J, et al. Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer. Aging (Albany NY). 2019;11:5035-5057 pubmed publisher |
| Xiao Y, Liang M, Liu C, Wang Y, Zeng Y, Zhou J, et al. Overexpression of P16 reversed the MDR1-mediated DDP resistance in the cervical adenocarcinoma by activating the ERK1/2 signaling pathway. Cell Div. 2019;14:6 pubmed publisher |
| Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, et al. Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer. Mol Cancer Res. 2019;: pubmed publisher |
| Wang H, Meng X, Piao L, Inoue A, Xu W, Yu C, et al. Cathepsin S Deficiency Mitigated Chronic Stress-Related Neointimal Hyperplasia in Mice. J Am Heart Assoc. 2019;8:e011994 pubmed publisher |
| Zhang X, Zhu J, Chen X, Jie Qiong Z, Li X, Luo L, et al. Interferon Regulatory Factor 3 Deficiency Induces Age-Related Alterations of the Retina in Young and Old Mice. Front Cell Neurosci. 2019;13:272 pubmed publisher |
| Wang Z, Chen Z, Jiang Z, Luo P, Liu L, Huang Y, et al. Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents. Nat Commun. 2019;10:2538 pubmed publisher |
| Liang J, Li Q, Cai W, Zhang X, Yang B, Li X, et al. Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells. Br J Pharmacol. 2019;176:3206-3219 pubmed publisher |
| Wang S, Wang H, Sun B, Li D, Wu J, Li J, et al. Acetyl-11-keto-β-boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular carcinoma cells in vitro and in vivo. Fundam Clin Pharmacol. 2019;: pubmed publisher |
| An J, Naruse T, Hinohara K, Soejima Y, Sawabe M, Nakagawa Y, et al. MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages. J Mol Cell Cardiol. 2019;133:26-35 pubmed publisher |
| Li Z, Zhu T, Xu Y, Wu C, Chen J, Ren Y, et al. A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma. Am J Cancer Res. 2019;9:699-713 pubmed |
| Godavarthy P, Kumar R, Herkt S, Pereira R, Hayduk N, Weissenberger E, et al. The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis. Haematologica. 2019;: pubmed publisher |
| Liu N, Matsumura H, Kato T, Ichinose S, Takada A, Namiki T, et al. Stem cell competition orchestrates skin homeostasis and ageing. Nature. 2019;568:344-350 pubmed publisher |
| Tu Q, Yang D, Zhang X, Jia X, An S, Yan L, et al. A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal. Dis Model Mech. 2019;12: pubmed publisher |
| Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, et al. Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability. BMC Cancer. 2019;19:262 pubmed publisher |
| Yang D, Xiao C, Long F, Wu W, Huang M, Qu L, et al. Fra-1 plays a critical role in angiotensin II-induced vascular senescence. FASEB J. 2019;33:7603-7614 pubmed publisher |
| Xu S, Wu W, Huang H, Huang R, Xie L, Su A, et al. The p53/miRNAs/Ccna2 pathway serves as a novel regulator of cellular senescence: Complement of the canonical p53/p21 pathway. Aging Cell. 2019;18:e12918 pubmed publisher |
| Sui A, Xu Y, Pan B, Guo T, Wu J, Shen Y, et al. Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. J Cell Physiol. 2019;: pubmed publisher |
| Cao Z, Xue J, Cheng Y, Wang J, Liu Y, Li H, et al. MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1. Oncogene. 2019;38:4835-4855 pubmed publisher |
| Xiong Y, Li T, Assani G, Ling H, Zhou Q, Zeng Y, et al. Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo. Biomed Pharmacother. 2019;112:108602 pubmed publisher |
| Cho W, Jin X, Pang J, Wang Y, Mivechi N, Moskophidis D. The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways. Mol Cell Biol. 2019;39: pubmed publisher |
| Li R, Liu Y, Xie J, Huang X, Zhang L, Liu H, et al. Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. Free Radic Biol Med. 2019;135:116-124 pubmed publisher |
| Yoon M, Kang S, Lee S, Woo T, Oh A, Park S, et al. p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation. Cell Death Dis. 2019;10:107 pubmed publisher |
| Saito N, Araya J, Ito S, Tsubouchi K, Minagawa S, Hara H, et al. Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis. J Immunol. 2019;202:1428-1440 pubmed publisher |
| Yun D, Wang H, Wang Y, Chen Y, Zhao Z, Ma J, et al. Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma. EBioMedicine. 2019;40:163-175 pubmed publisher |
| Su Y, Xu C, Sun Z, Liang Y, Li G, Tong T, et al. S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. Aging (Albany NY). 2019;11:549-572 pubmed publisher |
| Wei X, Luo D, Yan Y, Yu H, Sun L, Wang C, et al. Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways. Exp Eye Res. 2019;180:174-183 pubmed publisher |
| Liang X, Ding Y, Lin F, Zhang Y, Zhou X, Meng Q, et al. Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. FASEB J. 2019;33:4559-4570 pubmed publisher |
| Stojiljkovic M, Ain Q, Bondeva T, Heller R, Schmeer C, Witte O. Phenotypic and functional differences between senescent and aged murine microglia. Neurobiol Aging. 2019;74:56-69 pubmed publisher |
| Wu S, Yan W, Qiu B, Liao Y, Gu J, Wei S, et al. Aberrant methylation-induced dysfunction of p16 is associated with osteoblast activation caused by fluoride. Environ Toxicol. 2019;34:37-47 pubmed publisher |
| Ming J, Wu S, You T, Wang X, Yu C, Luo P, et al. Histone Deacetylation in the Promoter of p16 Is Involved in Fluoride-Induced Human Osteoblast Activation via the Inhibition of Sp1 Binding. Biol Trace Elem Res. 2019;188:373-383 pubmed publisher |
| Chen Y, Tzeng D, Huang Y, Lin C, Lo U, Wu C, et al. Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways. Cancers (Basel). 2018;11: pubmed publisher |
| Márton M, Tihanyi N, Gyulavári P, Banhegyi G, Kapuy O. NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism. PLoS ONE. 2018;13:e0207949 pubmed publisher |
| Mohamed A, Shah N, Hettmer S, Vargesson N, Wackerhage H. Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma. Sci Rep. 2018;8:15674 pubmed publisher |
| Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, et al. Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. Mol Pharm. 2018;15:4974-4984 pubmed publisher |
| Wang Z, Wang Y, Wang S, Meng X, Song F, Huo W, et al. Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production. Front Cell Infect Microbiol. 2018;8:279 pubmed publisher |
| Beaver L, Lӧhr C, Clarke J, Glasser S, Watson G, Wong C, et al. Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice. Curr Dev Nutr. 2018;2:nzy002 pubmed publisher |
| Sun Y, Zheng Y, Wang C, Liu Y. Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells. Cell Death Dis. 2018;9:753 pubmed publisher |
| Roselló Díez A, Madisen L, Bastide S, Zeng H, Joyner A. Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice. PLoS Biol. 2018;16:e2005086 pubmed publisher |
| Li Y, Peng Z, Wang C, Li L, Leng Y, Chen R, et al. Novel role of PKR in palmitate-induced Sirt1 inactivation and endothelial cell senescence. Am J Physiol Heart Circ Physiol. 2018;315:H571-H580 pubmed publisher |
| Winkler C, Rouget R, Wu D, Beullens M, Van Eynde A, Bollen M. Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks. J Cell Sci. 2018;131: pubmed publisher |
| Hui K, Yeung P, Tam K, Chiang A. Counteracting survival functions of EBNA3C in Epstein-Barr virus (EBV)-driven lymphoproliferative diseases by combination of SAHA and bortezomib. Oncotarget. 2018;9:25101-25114 pubmed publisher |
| Liu Y, Wang L, Chen S, Zong Z, Guan X, Zhao Y. LncRNA ABHD11-AS1 promotes the development of endometrial carcinoma by targeting cyclin D1. J Cell Mol Med. 2018;: pubmed publisher |
| Wang H, Zhong Q, Yang T, Qi Y, Fu M, Yang X, et al. Comparative characterization of SHED and DPSCs during extended cultivation in vitro. Mol Med Rep. 2018;17:6551-6559 pubmed publisher |
| Prabakaran A, Karakkat J, Vijayan R, Chalissery J, Ibrahim M, Kaimala S, et al. Identification of early indicators of altered metabolism in normal development using a rodent model system. Dis Model Mech. 2018;11: pubmed publisher |
| Yang F, Yi M, Liu Y, Wang Q, Hu Y, Deng H. Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis. J Proteome Res. 2018;17:1091-1100 pubmed publisher |
| Thangavel C, Boopathi E, Liu Y, McNair C, Haber A, Perepelyuk M, et al. Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. Clin Cancer Res. 2018;24:1402-1414 pubmed publisher |
| Xing S, Li J, Chen L, Yang Y, He P, Li J, et al. Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3. Mech Ageing Dev. 2018;175:1-6 pubmed publisher |
| Zhang J, Zhang Y, Peng J, Li N, Xiong X, Ma Q, et al. Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p. Mech Ageing Dev. 2018;169:10-18 pubmed publisher |
| Liu A, Guo E, Yang J, Yang Y, Liu S, Jiang X, et al. Young plasma reverses age-dependent alterations in hepatic function through the restoration of autophagy. Aging Cell. 2018;17: pubmed publisher |
| Masaldan S, Clatworthy S, Gamell C, Meggyesy P, Rigopoulos A, Haupt S, et al. Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis. Redox Biol. 2018;14:100-115 pubmed publisher |
| Tamgue O, Lei M. Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation. Asian Pac J Cancer Prev. 2017;18:2519-2526 pubmed |
| Watanabe R, Fujita N, Sato Y, Kobayashi T, Morita M, Oike T, et al. Enpp1 is an anti-aging factor that regulates Klotho under phosphate overload conditions. Sci Rep. 2017;7:7786 pubmed publisher |
| Frescas D, Hall B, Strom E, Virtuoso L, Gupta M, Gleiberman A, et al. Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a) in vivo are not necessarily senescent. Cell Cycle. 2017;16:1526-1533 pubmed publisher |
| Peng C, Hu W, Weng X, Tong R, Cheng S, Ding C, et al. Over Expression of Long Non-Coding RNA PANDA Promotes Hepatocellular Carcinoma by Inhibiting Senescence Associated Inflammatory Factor IL8. Sci Rep. 2017;7:4186 pubmed publisher |
| Xia M, Zhao X, Huang Q, Sun H, Sun C, Yuan J, et al. Activation of Wnt/?-catenin signaling by lithium chloride attenuates d-galactose-induced neurodegeneration in the auditory cortex of a rat model of aging. FEBS Open Bio. 2017;7:759-776 pubmed publisher |
| Lei Y, Yang G, Hu L, Piao L, Inoue A, Jiang H, et al. Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress. Int J Cardiol. 2017;243:413-420 pubmed publisher |
| Wu W, Hou C, Mu X, Sun C, Zhu Y, Wang M, et al. H2S Donor NaHS Changes the Production of Endogenous H2S and NO in D-Galactose-Induced Accelerated Ageing. Oxid Med Cell Longev. 2017;2017:5707830 pubmed publisher |
| Wang S, Cao Z, Xue J, Li H, Jiang W, Cheng Y, et al. A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. J Biol Chem. 2017;292:8207-8222 pubmed publisher |
| Zhang J, Liu W, Peng J, Ma Q, Peng J, Luo X. miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1. Mech Ageing Dev. 2017;164:8-19 pubmed publisher |
| Harvey E, Zhang H, Sepulveda P, Garcia S, Sweeney D, Choudry F, et al. Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability. Stem Cells Transl Med. 2017;6:1399-1411 pubmed publisher |
| Altieri P, Murialdo R, Barisione C, Lazzarini E, Garibaldi S, Fabbi P, et al. 5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1. Br J Pharmacol. 2017;174:3713-3726 pubmed publisher |
| Yan P, Xu J, Zeng Y, Dong G, Cao H, Zheng M, et al. Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys. J Assist Reprod Genet. 2017;34:535-545 pubmed publisher |
| Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, et al. CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells. Cell Death Dis. 2017;8:e2546 pubmed publisher |
| Zhang W, Xiong Y, Zhu T, Xiong A, Bao H, Cheng X. MicroRNA let-7g inhibited hypoxia-induced proliferation of PASMCs via G0/G1 cell cycle arrest by targeting c-myc. Life Sci. 2017;170:9-15 pubmed publisher |
| Nomanbhoy T, Sharma G, Brown H, Wu J, Aban A, Vogeti S, et al. Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response. Biochemistry. 2016;55:5434-41 pubmed publisher |
| Marquez Vilendrer S, Thompson K, Lu L, Reisman D. Mechanism of BRG1 silencing in primary cancers. Oncotarget. 2016;7:56153-56169 pubmed publisher |
| Lazzarini E, Balbi C, Altieri P, Pfeffer U, Gambini E, Canepa M, et al. The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity. Sci Rep. 2016;6:29994 pubmed publisher |
| Wang Z, Zhang J, Zeng Y, Sun S, Zhang J, Zhang B, et al. Knockout of 4.1B triggers malignant transformation in SV40T-immortalized mouse embryo fibroblast cells. Mol Carcinog. 2017;56:538-549 pubmed publisher |
| Chen H, Long Y, Guo L. Antiaging Effect of Inula britannica on Aging Mouse Model Induced by D-Galactose. Evid Based Complement Alternat Med. 2016;2016:6049083 pubmed publisher |
| Li W, Wang Z, Liu S, Hu Y, Yin M, Lu Y. N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by A? 1-42 via the CB2 Receptor. Stem Cells Int. 2016;2016:7419389 pubmed publisher |
| Xu X, Pang J, Chen Y, Bucala R, Zhang Y, Ren J. Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation. Sci Rep. 2016;6:22488 pubmed publisher |
| Feng T, Shao F, Wu Q, Zhang X, Xu D, Qian K, et al. miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation. Oncotarget. 2016;7:16205-16 pubmed publisher |
| Altieri P, Barisione C, Lazzarini E, Garuti A, Bezante G, Canepa M, et al. Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes. J Am Heart Assoc. 2016;5: pubmed publisher |
| Rajendran P, Dashwood W, Li L, Kang Y, Kim E, Johnson G, et al. Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. Clin Epigenetics. 2015;7:102 pubmed publisher |
| Huang W, Zhong W, Xu J, Su B, Huang G, Du J, et al. Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation. Oncol Rep. 2015;34:1510-6 pubmed publisher |
| Bader S, Zajac M, Friess T, Ruge E, Rieder N, Gierke B, et al. Evaluation of Protein Profiles From Treated Xenograft Tumor Models Identifies an Antibody Panel for Formalin-fixed and Paraffin-embedded (FFPE) Tissue Analysis by Reverse Phase Protein Arrays (RPPA). Mol Cell Proteomics. 2015;14:2775-85 pubmed publisher |
| Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed |
| Al Wahab Z, Mert I, Tebbe C, Chhina J, Hijaz M, Morris R, et al. Metformin prevents aggressive ovarian cancer growth driven by high-energy diet: similarity with calorie restriction. Oncotarget. 2015;6:10908-23 pubmed |
| Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher |
| Hua Y, Robinson T, Cao Y, Shi G, Ren J, Nair S. Cathepsin K knockout alleviates aging-induced cardiac dysfunction. Aging Cell. 2015;14:345-51 pubmed publisher |
| Damsky W, Micevic G, Meeth K, Muthusamy V, Curley D, Santhanakrishnan M, et al. mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation. Cancer Cell. 2015;27:41-56 pubmed publisher |
