This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Histone H2A.X
catalog :
10856-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 31
Reference
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu B, et al. Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting. Theranostics. 2020;10:6384-6398 pubmed publisher
Dong X, Cheng R, Zhu S, Liu H, Zhou R, Zhang C, et al. A Heterojunction Structured WO2.9-WSe2 Nanoradiosensitizer Increases Local Tumor Ablation and Checkpoint Blockade Immunotherapy upon Low Radiation Dose. ACS Nano. 2020;14:5400-5416 pubmed publisher
Jia Y, Jin H, Gao L, Yang X, Wang F, Ding H, et al. A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. J Cell Mol Med. 2020;24:5304-5316 pubmed publisher
Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, et al. 5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells. Chem Biol Interact. 2019;315:108886 pubmed publisher
Fan P, Li Z, Zuo C, Fang M. Promotion effects of mono-2-ethyhexyl phthalate (MEHP) on migration and invasion of human melanoma cells via activation of TGF-β signals. Cell Biochem Funct. 2019;: pubmed publisher
Pan C, Lang H, Zhang T, Wang R, Lin X, Shi P, et al. Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts. Int J Mol Med. 2019;44:1629-1640 pubmed publisher
Zhou X, Zheng J, Tang Y, Lin Y, Wang L, Li Y, et al. EBV encoded miRNA BART8-3p promotes radioresistance in nasopharyngeal carcinoma by regulating ATM/ATR signaling pathway. Biosci Rep. 2019;39: pubmed publisher
Kaplan N, Wang J, Wray B, Patel P, Yang W, Peng H, et al. Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population. Invest Ophthalmol Vis Sci. 2019;60:3570-3583 pubmed publisher
Xu X, Wang D, Zheng C, Gao B, Fan J, Cheng P, et al. Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane. Theranostics. 2019;9:2252-2267 pubmed publisher
Currey N, Jahan Z, Caldon C, Tran P, Benthani F, De Lacavalerie P, et al. Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer. Cell Mol Gastroenterol Hepatol. 2019;7:819-839 pubmed publisher
Zhou R, Wang H, Yang Y, Zhang C, Dong X, Du J, et al. Tumor microenvironment-manipulated radiocatalytic sensitizer based on bismuth heteropolytungstate for radiotherapy enhancement. Biomaterials. 2018;189:11-22 pubmed publisher
Zhou L, Wang H, Jing J, Yu L, Wu X, Lu Z. Morroniside regulates hair growth and cycle transition via activation of the Wnt/?-catenin signaling pathway. Sci Rep. 2018;8:13785 pubmed publisher
Liu X, Wu J, Shi W, Shi W, Liu H, Wu X. Lead Induces Genotoxicity via Oxidative Stress and Promoter Methylation of DNA Repair Genes in Human Lymphoblastoid TK6 Cells. Med Sci Monit. 2018;24:4295-4304 pubmed publisher
Chen X, Wu L, Li D, Xu Y, Zhang L, Niu K, et al. Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1?. Cancer Med. 2018;7:3834-3847 pubmed publisher
Liu Q, Zhao Y, Zheng L, Zhu X, Cui L, Cao Y. The Glycosylphosphatidylinositol Transamidase Complex Subunit PbGPI16 of Plasmodium berghei Is Important for Inducing Experimental Cerebral Malaria. Infect Immun. 2018;86: pubmed publisher
Hong F, Wan L, Liu J, Huang K, Xiao Z, Zhang Y, et al. Histone methylation regulates Hif-1 signaling cascade in activation of hepatic stellate cells. FEBS Open Bio. 2018;8:406-415 pubmed publisher
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, et al. Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells. Cell Prolif. 2018;51:e12450 pubmed publisher
Xu W, Li F, Xu Z, Sun B, Cao J, Liu Y. Role of Peroxiredoxin 2 in the Protection Against Ferrous Sulfate-Induced Oxidative and Inflammatory Injury in PC12 Cells. Cell Mol Neurobiol. 2018;38:735-745 pubmed publisher
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J. Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver. Plant Foods Hum Nutr. 2017;72:425-431 pubmed publisher
Tang Q, Ji F, Wang J, Guo L, Li Y, Bao Y. Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin. Eur J Pharm Sci. 2017;109:223-232 pubmed publisher
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J, et al. Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain. J Agric Food Chem. 2017;65:5973-5984 pubmed publisher
Mikuła Pietrasik J, Uruski P, Pakuła M, Maksin K, Szubert S, Wozniak A, et al. Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells. Free Radic Biol Med. 2017;110:270-279 pubmed publisher
Yong Y, Zhang C, Gu Z, Du J, Guo Z, Dong X, et al. Polyoxometalate-Based Radiosensitization Platform for Treating Hypoxic Tumors by Attenuating Radioresistance and Enhancing Radiation Response. ACS Nano. 2017;11:7164-7176 pubmed publisher
Xu W, Li F, Xu Z, Sun B, Cao J, Liu Y. Tert-butylhydroquinone protects PC12 cells against ferrous sulfate-induced oxidative and inflammatory injury via the Nrf2/ARE pathway. Chem Biol Interact. 2017;273:28-36 pubmed publisher
Zhao H, Han Z, Liu X, Gu J, Tang F, Wei G, et al. The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes. J Biol Chem. 2017;292:8507-8519 pubmed publisher
Guan J, Zhao Q, Mao W. Nuclear PTEN interferes with binding of Ku70 at double-strand breaks through post-translational poly(ADP-ribosyl)ation. Biochim Biophys Acta. 2016;1863:3106-3115 pubmed publisher
Hou S, Li N, Zhang Q, Li H, Wei X, Hao T, et al. XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE. Cell Death Dis. 2016;7:e2409 pubmed publisher
Xu Y, Wu D, Fan Y, Li P, DU H, Shi J, et al. Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-?B signaling in murine breast cancer cells. Oncol Lett. 2016;12:2632-2640 pubmed
Xu Y, Wu D, Fan Y, Li P, DU H, Shi J, et al. Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling. Radiat Res. 2016;185:77-86 pubmed publisher
Wu P, Zhu X, Jin W, Hao S, Liu Q, Zhang L. Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells. Biochem Biophys Res Commun. 2015;460:183-90 pubmed publisher
Qi W, Wang R, Chen H, Wang X, Xiao T, Boldogh I, et al. BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51. J Cell Sci. 2015;128:317-30 pubmed publisher
product information
CatalogNo :
10856-1-AP
AntigenName :
Histone H2A.X
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
H2A histone family, member X
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC013416
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:200 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.