| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 4d
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- western blot; rat; loading ...; fig 3a
| He Q, Li Z, Meng C, Wu J, Zhao Y, Zhao J. Parkin-Dependent Mitophagy is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats. Cells. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 5a
| Ast T, Meisel J, Patra S, Wang H, Grange R, Kim S, et al. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019;: pubmed publisher |
- western blot; rat; loading ...; fig 4a
- western blot; mouse; loading ...; fig 3b
- western blot; human; loading ...; fig 8a
| Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed |
- western blot; rat; 1:1000; loading ...; fig 8c
| Duan H, Lee J, Moon S, Arora D, Li Y, Lim H, et al. Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic ?-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress. J Med Chem. 2016;59:7783-800 pubmed publisher |
- western blot; human; fig 4
| Cabral W, Ishikawa M, Garten M, Makareeva E, Sargent B, Weis M, et al. Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta. PLoS Genet. 2016;12:e1006156 pubmed publisher |
- immunoprecipitation; human; fig 4
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| Wang X, Xia H, Qin H, Kang X, Hu H, Zheng J, et al. 20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway. J Cell Biochem. 2019;120:5085-5096 pubmed publisher |
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| Lin W, Chakraborty A, Huang S, Wang P, Hsieh Y, Chien K, et al. Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase. Cell Rep. 2018;24:2733-2745.e7 pubmed publisher |
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| Chen J, Zhang Z, Song J, Liu Q, Wang C, Huang Z, et al. 18?-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma. Sci Rep. 2018;8:9365 pubmed publisher |
| Geng W, Qin F, Ren J, Xiao S, Wang A. Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice. Exp Cell Res. 2018;369:243-250 pubmed publisher |
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| Tanaka I, Sato M, Kato T, Goto D, Kakumu T, Miyazawa A, et al. eIF2?, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer. Cancer Sci. 2018;109:1843-1852 pubmed publisher |
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| Tsai T, Lai K, Su J, Wu Y, Sheu J. 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway. Mar Drugs. 2018;16: pubmed publisher |
| Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T. Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells. Oxid Med Cell Longev. 2018;2018:3853409 pubmed publisher |
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| Beauvais G, Rodriguez Losada N, Ying L, Zakirova Z, Watson J, Readhead B, et al. Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain. Neuroscience. 2018;371:455-468 pubmed publisher |
| Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, et al. Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1. Autophagy. 2018;14:336-346 pubmed publisher |
| Pan S, Jia Y, Yang X, Cai D, Liu Z, Song H, et al. Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-prot. Eur J Nutr. 2018;57:991-1001 pubmed publisher |
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| Rao Z, Sun J, Pan X, Chen Z, Sun H, Zhang P, et al. Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver-Resident Macrophage M2 Polarization via C/EBP Homologous Protein-Mediated Endoplasmic Reticulum Stress. Front Immunol. 2017;8:1299 pubmed publisher |
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| Maryam A, Mehmood T, Zhang H, Li Y, Khan M, Ma T. Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress. Sci Rep. 2017;7:6242 pubmed publisher |
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| Duan H, Li Y, Arora D, Xu D, Lim H, Wang W. Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress. J Med Chem. 2017;60:6191-6204 pubmed publisher |
| Liu Y, Jiang Z, Zhou Y, Qiu H, Wang G, Luo Y, et al. β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway. Biomed Pharmacother. 2017;93:490-497 pubmed publisher |
| Kim H, Joe Y, Kim S, Park S, Park J, Chen Y, et al. Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2?-ATF4 pathway. Free Radic Biol Med. 2017;110:81-91 pubmed publisher |
| Rojas Rivera D, Delvaeye T, Roelandt R, Nerinckx W, Augustyns K, Vandenabeele P, et al. When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157. Cell Death Differ. 2017;24:1100-1110 pubmed publisher |
| Xia H, Zhu J, Wang J, Ren J, Cai Y, Wang F, et al. Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma. J Histochem Cytochem. 2017;65:285-294 pubmed publisher |
| Yin Y, Chen C, Chen J, Zhan R, Zhang Q, Xu X, et al. Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR. Cell Signal. 2017;35:154-162 pubmed publisher |
| Wang Y, Gu Y, Liu M, Bai Y, Liang L, Wang H. TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity. Oxid Med Cell Longev. 2017;2017:4310475 pubmed publisher |
| Wolczyk M, Podszywalow Bartnicka P, Bugajski L, Piwocka K. Stress granules assembly affects detection of mRNA in living cells by the NanoFlares; an important aspect of the technology. Biochim Biophys Acta Gen Subj. 2017;1861:1024-1035 pubmed publisher |
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| Lin J, Wang R, Chen J, Chiu C, Liao M, Wu Y. Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction. Int J Mol Sci. 2016;17: pubmed |
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| Hsieh Y, Lo H, Yang P. EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. Am J Cancer Res. 2016;6:1661-80 pubmed |
| Zhang W, Chen L, Shen Y, Xu J. Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway. Toxicol In Vitro. 2016;36:186-196 pubmed publisher |
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| Fujita Y, Makishima M, Bhawal U. Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice. Biochem Biophys Res Commun. 2016;469:477-82 pubmed publisher |
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| Gao H, Yan P, Zhang S, Nie S, Huang F, Han H, et al. Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway. Brain Behav Immun. 2016;57:314-325 pubmed publisher |
| Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A. TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress. J Cell Biochem. 2016;117:500-9 pubmed publisher |
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| Xu D, Su C, Song X, Shi Q, Fu J, Hu L, et al. Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release. Chem Res Toxicol. 2015;28:1326-37 pubmed publisher |
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