This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
KPNA2
catalog :
10819-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Reference
Yang F, Li S, Cheng Y, Li J, Han X. Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells. Life Sci. 2020;252:117611 pubmed publisher
Fu F, Zhang Y, Gao Z, Zhao Y, Wen Z, Han H, et al. Development and validation of a five-gene model to predict postoperative brain metastasis in operable lung adenocarcinoma. Int J Cancer. 2020;147:584-592 pubmed publisher
Shelkovnikova T, An H, Skelt L, Tregoning J, Humphreys I, Buchman V. Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;29:4496-4508.e4 pubmed publisher
Su M, Wang P, Wang X, Zhang M, Wei S, Liu K, et al. Nuclear CD44 Mediated by Importin β Participated in Naïve Genes Transcriptional Regulation in C3A-iCSCs. Int J Biol Sci. 2019;15:1252-1260 pubmed publisher
Ma A, Tang M, Zhang L, Wang B, Yang Z, Liu Y, et al. USP1 inhibition destabilizes KPNA2 and suppresses breast cancer metastasis. Oncogene. 2019;38:2405-2419 pubmed publisher
Wang C, Yu C, Huang Y, Yi J, Cheng H, Kao H, et al. Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin-1β-induced matrix metalloproteinase expression in oral cancer. Head Neck. 2018;40:1719-1733 pubmed publisher
Tsai C, Chi H, Chi L, Yang H, Tsai M, Lee K, et al. Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy. FASEB J. 2018;32:2601-2614 pubmed publisher
Yu L, Wang G, Zhang Q, Gao L, Huang R, Chen Y, et al. Karyopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancer. Oncol Lett. 2017;13:1194-1200 pubmed publisher
Lin W, Xu P, Guo Y, Jia Q, Tao T. Nuclear import of Nkx2-2 is mediated by multiple pathways. Biochem Biophys Res Commun. 2017;482:1511-1516 pubmed publisher
Chen X, Zhu Y, Wang Z, Zhu H, Pan Q, Su S, et al. mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances. J Proteomics. 2016;136:13-24 pubmed publisher
Wang C, Wang C, Wu Y, Feng H, Liu P, Chang Y, et al. Quantitative proteomics reveals a novel role of karyopherin alpha 2 in cell migration through the regulation of vimentin-pErk protein complex levels in lung cancer. J Proteome Res. 2015;14:1739-51 pubmed publisher
product information
CatalogNo :
10819-1-AP
AntigenName :
KPNA2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Importin subunit alpha 2, IPOA1, Karyopherin subunit alpha 2, KPNA2, QIP2, RAG cohort protein 1, RCH1, SRP1, SRP1 alpha, SRP1alpha
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC005978
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.