This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Geminin
catalog :
10802-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
hamsters, human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; hamsters; 1:400; fig 8
Chatalic K, Konijnenberg M, Nonnekens J, De Blois E, Hoeben S, de Ridder C, et al. In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies. Theranostics. 2016;6:104-17 pubmed publisher
Gerakopoulos V, Ngo P, Tsiokas L. Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Life Sci Alliance. 2020;3: pubmed publisher
Venneker S, Kruisselbrink A, Briaire de Bruijn I, de Jong Y, Van Wijnen A, Danen E, et al. Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status. Cancers (Basel). 2019;11: pubmed publisher
Siril Y, Kouketsu A, Oikawa M, Takahashi T, Kumamoto H. Immunohistochemical assessment of chromatin licensing and DNA replication factor 1, geminin, and γ-H2A.X in oral epithelial precursor lesions and squamous cell carcinoma. J Oral Pathol Med. 2019;: pubmed publisher
Kopper O, de Witte C, Lõhmussaar K, Valle Inclan J, Hami N, Kester L, et al. An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity. Nat Med. 2019;25:838-849 pubmed publisher
van den Tempel N, Naipal K, Raams A, van Gent D, Franckena M, Boormans J, et al. Ex vivo assays to predict enhanced chemosensitization by hyperthermia in urothelial cancer of the bladder. PLoS ONE. 2018;13:e0209101 pubmed publisher
Castroviejo Bermejo M, Cruz C, Llop Guevara A, Gutierrez Enriquez S, Ducy M, Ibrahim Y, et al. A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation. EMBO Mol Med. 2018;10: pubmed publisher
Nacson J, Krais J, Bernhardy A, Clausen E, Feng W, Wang Y, et al. BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance. Cell Rep. 2018;24:3513-3527.e7 pubmed publisher
Zhang M, Yao F, Luan H, Zhao W, Jing T, Zhang S, et al. APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica. Sci Rep. 2016;6:39047 pubmed publisher
Bhide S, Thway K, Lee J, Wong K, Clarke P, Newbold K, et al. Delayed DNA double-strand break repair following platin-based chemotherapy predicts treatment response in head and neck squamous cell carcinoma. Br J Cancer. 2016;115:825-30 pubmed publisher
Cheng F, Twardowski L, Reifenberg K, Winter K, Canisius A, Pross E, et al. Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice. PLoS ONE. 2016;11:e0157311 pubmed publisher
Fleury H, Carmona E, Morin V, Meunier L, Masson J, Tonin P, et al. Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines. Oncotarget. 2017;8:40152-40168 pubmed publisher
Wang Y, Bernhardy A, Cruz C, Krais J, Nacson J, Nicolas E, et al. The BRCA1-?11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. Cancer Res. 2016;76:2778-90 pubmed publisher
Schaaf L, Schwab M, Ulmer C, Heine S, Mürdter T, Schmid J, et al. Hyperthermia Synergizes with Chemotherapy by Inhibiting PARP1-Dependent DNA Replication Arrest. Cancer Res. 2016;76:2868-75 pubmed publisher
Cates J, Memoli V, Gonzalez R. Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma. Virchows Arch. 2015;467:211-6 pubmed publisher
Waddell N, Pajic M, Patch A, Chang D, Kassahn K, Bailey P, et al. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature. 2015;518:495-501 pubmed publisher
Tomono A, Itoh T, Yanagita E, Imagawa N, Kakeji Y. Cell cycle kinetic analysis of colorectal neoplasms using a new automated immunohistochemistry-based cell cycle detection method. Medicine (Baltimore). 2015;94:e501 pubmed publisher
product information
CatalogNo :
10802-1-AP
AntigenName :
Geminin
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
geminin, DNA replication inhibitor
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Gem, Geminin, GMNN, RP3 369A17.3
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC005185
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:200 ; IHC 1:200 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.