This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
LDLR
catalog :
10785-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; fig 3
Zhou J, Gao S, Chen J, Zhao R, Yang X. Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. Lipids Health Dis. 2016;15:119 pubmed publisher
Lai W, Li D, Wang Q, Nan X, Xiang Z, Ma Y, et al. A Protein Corona Adsorbed to a Bacterial Magnetosome Affects Its Cellular Uptake. Int J Nanomedicine. 2020;15:1481-1498 pubmed publisher
Guo H, Feng C, Zhang W, Luo Z, Zhang H, Zhang T, et al. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases. Nat Commun. 2019;10:1981 pubmed publisher
Zhu L, Wu G, Yang X, Jia X, Li J, Bai X, et al. Low density lipoprotein mimics insulin action on autophagy and glucose uptake in endothelial cells. Sci Rep. 2019;9:3020 pubmed publisher
Yang D, Hu C, Deng X, Bai Y, Cao H, Guo J, et al. Therapeutic Effect of Chitooligosaccharide Tablets on Lipids in High-Fat Diets Induced Hyperlipidemic Rats. Molecules. 2019;24: pubmed publisher
Guo S, Lu J, Zhuo Y, Xiao M, Xue X, Zhong S, et al. Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages. Redox Biol. 2019;21:101069 pubmed publisher
Zhong S, Li L, Zhang Y, Zhang L, Lu J, Guo S, et al. Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation. J Clin Invest. 2019;129:252-267 pubmed publisher
Cao S, Xu P, Yan J, Liu H, Liu L, Cheng L, et al. Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells. J Cell Biochem. 2018;: pubmed publisher
Jiang Y, Fu C, Liu G, Guo J, Su Z. Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats. Food Nutr Res. 2018;62: pubmed publisher
Zhou C, Gao Z, Wang J, Wu M, Hu S, Chen F, et al. Lead exposure induces Alzheimers's disease (AD)-like pathology and disturbes cholesterol metabolism in the young rat brain. Toxicol Lett. 2018;296:173-183 pubmed publisher
Hao J, Huang K, Chen C, Liang Y, Wang Y, Zhang X, et al. Polydatin Improves Glucose and Lipid Metabolisms in Insulin-Resistant HepG2 Cells through the AMPK Pathway. Biol Pharm Bull. 2018;41:891-898 pubmed publisher
Zhang K, Chen Y, Zhang T, Huang L, Wang Y, Yin T, et al. A Novel Role of Id1 in Regulating Oscillatory Shear Stress-Mediated Lipid Uptake in Endothelial Cells. Ann Biomed Eng. 2018;46:849-863 pubmed publisher
Idriss A, Hu Y, Hou Z, Hu Y, Sun Q, Omer N, et al. Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation. Comp Biochem Physiol B Biochem Mol Biol. 2018;217:14-20 pubmed publisher
Bai X, Yang X, Li J, Ye Li -, Jia X, Xiong Z, et al. Cavin-1 regulates caveolae-mediated LDL transcytosis: crosstalk in an AMPK/eNOS/ NF-?B/Sp1 loop. Oncotarget. 2017;8:103985-103995 pubmed publisher
Chadwick A, Wang X, Musunuru K. In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing. Arterioscler Thromb Vasc Biol. 2017;37:1741-1747 pubmed publisher
Bian F, Cui J, Zheng T, Jin S. Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells. Int J Mol Med. 2017;39:629-635 pubmed publisher
Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, et al. Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification. Nutrients. 2016;8: pubmed
Wang Y, Han Y, Chai F, Xiang H, Huang T, Kou S, et al. The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4?/FTF-mediated CYP7A1 activation. Fitoterapia. 2016;115:111-121 pubmed publisher
Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R. Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets. J Agric Food Chem. 2016;64:7530-7539 pubmed
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, et al. Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection. J Virol. 2016;90:9632-9643 pubmed publisher
He K, Li X, Xiao Y, Yong Y, Zhang Z, Li S, et al. Hypolipidemic effects of Myrica rubra extracts and main compounds in C57BL/6j mice. Food Funct. 2016;7:3505-15 pubmed publisher
He K, Hu Y, Ma H, Zou Z, Xiao Y, Yang Y, et al. Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways. Biochim Biophys Acta. 2016;1862:1696-709 pubmed publisher
Sun L, Dong H, Zhang Z, Liu J, Hu Y, Ni Y, et al. Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism. Oncotarget. 2016;7:27627-40 pubmed publisher
Yuan Z, Lu X, Lei F, Chai Y, Wang Y, Jiang J, et al. TATA boxes in gene transcription and poly (A) tails in mRNA stability: New perspective on the effects of berberine. Sci Rep. 2015;5:18326 pubmed publisher
Liu M, Zhang W, Li X, Han J, Chen Y, Duan Y. Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. Biochem Biophys Res Commun. 2016;469:456-62 pubmed publisher
Liu J, Duan Y, Hu Y, Sun L, Wang S, Fu W, et al. Exogenous administration of chronic corticosterone affects hepatic cholesterol metabolism in broiler chickens showing long or short tonic immobility. Comp Biochem Physiol A Mol Integr Physiol. 2016;191:53-58 pubmed publisher
He K, Ye X, Wu H, Wang Y, Zou Z, Ning N, et al. The safety and anti-hypercholesterolemic effect of coptisine in Syrian golden hamsters. Lipids. 2015;50:185-94 pubmed publisher
product information
CatalogNo :
10785-1-AP
AntigenName :
LDLR
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
low density lipoprotein receptor
Immunogen :
Recombinant Protein
Species :
chicken, hamster, human, landrace, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
FH, FHC, LDL receptor, LDLR
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC014514
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.