This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CDK1
catalog :
10762-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 14
Reference
Ke C, Hou H, Li J, Su K, Huang C, Lin Y, et al. Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib. Cancers (Basel). 2020;12: pubmed publisher
Yang J, Zhu X, Jin M, Cao Z, Ren Y, Gu Z. Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway. Chem Biol Interact. 2019;316:108934 pubmed publisher
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, et al. Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway. J Exp Clin Cancer Res. 2019;38:139 pubmed publisher
Tseng H, Li S, Tsai K. Metformin Treatment Suppresses Melanoma Cell Growth and Motility Through Modulation of microRNA Expression. Cancers (Basel). 2019;11: pubmed publisher
Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, et al. CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner. J Cell Physiol. 2018;: pubmed publisher
Kueck T, Cassella E, Holler J, Kim B, Bieniasz P. The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression. elife. 2018;7: pubmed publisher
Zhu X, Li Z, Li T, Long F, Lv Y, Liu L, et al. Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma. Biomed Pharmacother. 2018;102:502-509 pubmed publisher
Zeng R, Liu Y, Jiang Z, Huang J, Wang Y, Li X, et al. EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma. Int J Oncol. 2018;: pubmed publisher
Shi W, Zhu X, Wang C, Zhang Y, Cai H, Li X, et al. PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT. Cell Death Dis. 2018;9:428 pubmed publisher
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z. Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling. Med Sci Monit. 2018;24:294-304 pubmed
Zhao Y, Yun D, Zou X, Jiang T, Li G, Hu L, et al. Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk. Am J Cancer Res. 2017;7:1937-1947 pubmed
Chong D, Ma L, Liu F, Zhang Z, Zhao S, Huo Q, et al. Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis. Anticancer Drugs. 2017;28:831-840 pubmed publisher
Ma D, Zhang R, Wen Y, Yin W, Bai D, Zheng G, et al. 1, 25(OH)2D3-induced interaction of vitamin D receptor with p50 subunit of NF-?B suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation. Biochem Biophys Res Commun. 2017;482:366-374 pubmed publisher
Dai B, Wang W, Liu R, Wang H, Zhang Y. Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma. Biomed Pharmacother. 2015;70:227-33 pubmed publisher
product information
CatalogNo :
10762-1-AP
AntigenName :
CDK1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cell division cycle 2, G1 to S and G2 to M
Immunogen :
Recombinant Protein
Species :
human, mouse
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CDC2, CDC28A, CDK1, Cell division protein kinase 1, Cyclin dependent kinase 1, p34 protein kinase
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC014563
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:500 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.