This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
NF-κB p65
catalog :
10745-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat, pigs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
citations: 348
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3a
Ding H, Zhang X, Su Y, Jia C, Dai C. GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation. Cell Mol Biol Lett. 2020;25:8 pubmed publisher
  • western blot; human; loading ...; fig 4a
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R. The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation. Aging (Albany NY). 2020;12:1685-1703 pubmed publisher
  • western blot; human; loading ...; fig 4b
Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed publisher
  • immunocytochemistry; rat; 1:200; loading ...; fig 6o
  • western blot; rat; loading ...; fig 6i
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  • western blot; African green monkey; loading ...; fig 5h
  • immunocytochemistry; human; loading ...; fig 5g
  • western blot; human; loading ...; fig 4c
Lee C, Aizawa K, Jiang J, Kung S, Jain R. JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli. Sci Adv. 2019;5:eaav0318 pubmed publisher
  • western blot; human; loading ...; fig 5a
Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, et al. Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways. Biochem Pharmacol. 2019;170:113642 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Yang L, Hong Q, Xu S, Kuang X, Di G, Liu G, et al. Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway. Mol Med Rep. 2019;20:4045-4258 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 8a, 12a
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Jin Y, Li Y, Wang X, Yang Y. Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways. Cancer Cell Int. 2019;19:220 pubmed publisher
  • western blot; human; loading ...; fig 4b
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
  • western blot; pigs ; 1:500; loading ...; fig 3
Sun P, Sun N, Yin W, Sun Y, Fan K, Guo J, et al. Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome. Vet Res. 2019;50:53 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2e
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s4
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang Y, et al. Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure. Stress. 2019;22:366-376 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5h
Hwang W, Lan H, Cheng W, Huang S, Yang M. Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol. 2019;12:10 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6a
Xin H, Wang C, Liu Z. miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα. BMC Cancer. 2019;19:30 pubmed publisher
  • western blot; human; loading ...; fig 4b
Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, et al. Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-?B signaling pathway. Mol Cancer. 2017;16:117 pubmed publisher
  • western blot; human; 1:2000; fig 7
Wu X, Liu W, Duan Z, Gao Y, Li S, Wang K, et al. The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration. Sci Rep. 2016;6:30563 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 1
  • western blot; human; 1:1000; fig 1
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
  • western blot; human; 1:1000; fig 4
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
  • immunocytochemistry; human; fig 4
Li X, Wang S, Zhu R, Li H, Han Q, Zhao R. Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NF?B-TLR signaling pathway. J Hematol Oncol. 2016;9:42 pubmed publisher
Li Y, Zhang M, Li F. LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. Histol Histopathol. 2020;:18245 pubmed publisher
Zhuang C, Liu G, Barkema H, Zhou M, Xu S, Ur Rahman S, et al. Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages. Front Microbiol. 2020;11:1461 pubmed publisher
Kong F, Li N, Tu T, Tao Y, Bi Y, Yuan D, et al. Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis. Lab Invest. 2020;: pubmed publisher
Zhao Y, Tang J, Yang D, Tang C, Chen J. Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells. J Dairy Sci. 2020;103:8350-8359 pubmed publisher
Wu Y, Wang Z, Fu X, Lin Z, Yu K. Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies. Int Immunopharmacol. 2020;86:106713 pubmed publisher
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, et al. Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway. Biomed Res Int. 2020;2020:1860637 pubmed publisher
Zhang L, Yang Y, Liao Z, Liu Q, Lei X, Li M, et al. Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade. Theranostics. 2020;10:6638-6660 pubmed publisher
Gao Z, Sui J, Fan R, Qu W, Dong X, Sun D. Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling. Drug Des Devel Ther. 2020;14:1971-1982 pubmed publisher
Lu J, Feng X, Zhang H, Wei Y, Yang Y, Tian Y, et al. Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise. Connect Tissue Res. 2020;:1-11 pubmed publisher
Liu Y, Tsai J, Weng Y, Hsu F. Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer. Biomed Pharmacother. 2020;128:110319 pubmed publisher
Jin X, Yuan Y, Zhang C, Zhou Y, Song Y, Wei Z, et al. Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway. J Vet Sci. 2020;21:e50 pubmed publisher
Kang N, Cao S, Jiang B, Zhang Q, Donkor P, Zhu Y, et al. Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells. Toxicol In Vitro. 2020;67:104885 pubmed publisher
Liu Z, Wang P, Lu S, Guo R, Gao W, Tong H, et al. Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury. Cell Calcium. 2020;88:102198 pubmed publisher
Sun Q, Fan G, Zhuo Q, Dai W, Ye Z, Ji S, et al. Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop. Cell Prolif. 2020;53:e12816 pubmed publisher
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y. ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells. Int J Oncol. 2020;56:1162-1174 pubmed publisher
Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, et al. Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling. Aquaculture. 2020;520:734969 pubmed publisher
Zhang K, Hussain T, Wang J, Li M, Wang W, Ma X, et al. Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling. Front Microbiol. 2020;11:433 pubmed publisher
Yang F, Li S, Cheng Y, Li J, Han X. Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells. Life Sci. 2020;252:117611 pubmed publisher
Huang Y, Qiu L, Mi X, Zhang Z, Xu D, Tao X, et al. Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice. Food Funct. 2020;11:3459-3470 pubmed publisher
Almoiliqy M, Wen J, Xu B, Sun Y, Lian M, Li Y, et al. Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53. Acta Pharmacol Sin. 2020;41:1208-1222 pubmed publisher
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, et al. Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression. Cell Commun Signal. 2020;18:51 pubmed publisher
Liu L, Xu Y, Dai H, Tan S, Mao X, Chen Z. Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway. Cell Biosci. 2020;10:42 pubmed publisher
Zhang X, Feng J, Su S, Huang L. Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl4-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling. Pharm Biol. 2020;58:239-246 pubmed publisher
Zhang Y, Cui N, Zheng G. Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation. Oncol Lett. 2020;19:1975-1984 pubmed publisher
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, et al. The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study. Food Funct. 2020;11:2654-2666 pubmed publisher
Yang B, Liu Y, Cui Y, Song D, Zhang G, Ma S, et al. RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation. PLoS Pathog. 2020;16:e1008387 pubmed publisher
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, et al. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020;193:110364 pubmed publisher
Chen Y, Feng B, Yuan Y, Hu J, Zhao W, Jiang H, et al. Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway. Mediators Inflamm. 2020;2020:6318520 pubmed publisher
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y. Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells. Can J Physiol Pharmacol. 2020;98:156-161 pubmed publisher
He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, et al. Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells. Mol Med Rep. 2020;21:597-606 pubmed publisher
Wen J, Shen J, Zhou Y, Zhao X, Dai Z, Jin Y. Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway. Int J Mol Med. 2020;45:873-885 pubmed publisher
Lu J, Yan J, Yan J, Zhang L, Chen M, Chen Q, et al. Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis. Biomed Pharmacother. 2020;122:109777 pubmed publisher
Tian C, Gao F, Li X, Li Z. Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model. Exp Mol Pathol. 2020;113:104373 pubmed publisher
Wu B, Song Q, Zhang Y, Wang C, Yang M, Zhang J, et al. Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization. Lipids Health Dis. 2020;19:4 pubmed publisher
Xia B, Yu J, He T, Liu X, Su J, Wang M, et al. Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea. FASEB J. 2020;34:2821-2839 pubmed publisher
Yan J, Du G, Qin X, Gao L. Baicalein attenuates the neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines, COX2/NF-κB expressions and regulation of metabolic abnormality. Int Immunopharmacol. 2020;79:106092 pubmed publisher
Hu M, Yang J, Qu L, Deng X, Duan Z, Fu R, et al. Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma. Food Funct. 2020;11:456-471 pubmed publisher
Zhang H, Chen Y, Chen Y, Li Y, Jia P, Ji S, et al. Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide. J Anim Sci. 2020;98: pubmed publisher
Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, et al. Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway. J Cell Mol Med. 2020;24:1488-1503 pubmed publisher
Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, et al. The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model. Life Sci. 2020;241:117115 pubmed publisher
Yoshioka Y, Sugino Y, Shibagaki F, Yamamuro A, Ishimaru Y, Maeda S. Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia. Eur J Pharmacol. 2020;866:172826 pubmed publisher
Li S, Li Q, Zhu Y, Hu W. GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells. Exp Cell Res. 2020;387:111745 pubmed publisher
Zhang Q, Zhao S, Zheng W, Fu H, Wu T, Hu F. Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome. Biosci Biotechnol Biochem. 2020;84:134-142 pubmed publisher
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher
Cerruela García G, Pérez Parra Toledano J, de Haro García A, García Pedrajas N. Influence of feature rankers in the construction of molecular activity prediction models. J Comput Aided Mol Des. 2019;: pubmed publisher
Wang X, Zhang Y, Zhao J, Cao L, Zhu L, Huang Y, et al. Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway. Toxins (Basel). 2019;11: pubmed publisher
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, et al. HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway. Neurotox Res. 2019;: pubmed publisher
Liu Y, Yin W, Wang J, Lei Y, Sun G, Li W, et al. KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly. Cells. 2019;8: pubmed publisher
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, et al. Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:3765898 pubmed publisher
Wang Z, Liang M, Li H, Cai L, Yang L. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Hu Y, Li Q, Pan Y, Xu L. Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome. Molecules. 2019;24: pubmed publisher
Liu X, Cui H, Niu H, Wang L, Li X, Sun J, et al. Hydrocortisone Suppresses Early Paraneoplastic Inflammation And Angiogenesis To Attenuate Early Hepatocellular Carcinoma Progression In Rats. Onco Targets Ther. 2019;12:9481-9493 pubmed publisher
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, et al. Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways. BMC Complement Altern Med. 2019;19:343 pubmed publisher
Wang Y, Kang W, Shang L, Song A, Ge S. N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts. Arch Oral Biol. 2019;110:104605 pubmed publisher
Wang X, Zhang Y, Cao L, Zhu L, Huang Y, Chen X, et al. Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets. Toxins (Basel). 2019;11: pubmed publisher
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, et al. Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway. Neuroscience. 2019;422:99-118 pubmed publisher
Zhao C, Zhou X, Qiu J, Xin D, Li T, Chu X, et al. Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury. Drug Des Devel Ther. 2019;13:3693-3704 pubmed publisher
Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan M, et al. Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage. Viruses. 2019;11: pubmed publisher
Zhu J, Kang J, Li X, Wang M, Shang M, Luo Y, et al. Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility. Clin Hemorheol Microcirc. 2019;: pubmed publisher
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, et al. MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection. RNA. 2019;: pubmed publisher
Huang X, Liu W, Zhou Y, Hao C, Zhou Y, Zhang C, et al. Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner. Int J Mol Med. 2019;44:2213-2222 pubmed publisher
Liu C, Ding R, Huang W, Miao L, Li J, Li Y. Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats. Pharmacology. 2019;:1-12 pubmed publisher
Gao S, Xu T, Guo H, Deng Q, Xun C, Liang W, et al. Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway. Life Sci. 2019;237:116978 pubmed publisher
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, et al. The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling. Mol Cell Biochem. 2019;: pubmed publisher
Bianco C, Thompson L, Mohr I. Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing. Proc Natl Acad Sci U S A. 2019;116:22583-22590 pubmed publisher
Liang S, Wang Z, Zhang Z, Chen K, Lv Z, Wang Y, et al. Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop. Aging (Albany NY). 2019;11:8664-8680 pubmed publisher
Wang K, Zheng M, Lester K, Han Z. Light-induced Nrf2-/- mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel. Sci Rep. 2019;9:14573 pubmed publisher
Li H, Chi X, Li R, Ouyang J, Chen Y. HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer. Int J Biol Sci. 2019;15:2438-2447 pubmed publisher
Wei F, Jiang Z, Sun H, Pu J, Sun Y, Wang M, et al. Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling. PLoS Pathog. 2019;15:e1008062 pubmed publisher
Shu G, Qiu Y, Hao J, Fu Q, Deng X. γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways. Food Funct. 2019;10:6858-6872 pubmed publisher
Liu Z, Tao B, Fan S, Pu Y, Xia H, Xu L. MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways. Oxid Med Cell Longev. 2019;2019:8948657 pubmed publisher
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, et al. Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal. Front Pharmacol. 2019;10:1030 pubmed publisher
Li Y, Huang T, Fu Y, Wang T, Zhao T, Guo S, et al. Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway. PLoS ONE. 2019;14:e0215886 pubmed publisher
Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y. Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate. Acta Biomater. 2019;100:415-426 pubmed publisher
Dai Y, Wu Z, Lang C, Zhang X, He S, Yang Q, et al. Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling. Theranostics. 2019;9:6063-6079 pubmed publisher
Liu Y, Zhao J, Lü M, Wang H, Tang F. Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice. Can J Physiol Pharmacol. 2019;: pubmed publisher
Fu Z, Lin L, Liu S, Qin M, He S, Zhu L, et al. Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer. Med Sci Monit. 2019;25:6836-6845 pubmed publisher
Tan P, Wang A, Chen H, Du Y, Qian B, Shi H, et al. SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis. Exp Cell Res. 2019;384:111606 pubmed publisher
Wu X, Kong Q, Zhan L, Qiu Z, Huang Q, Song X. TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury. Inflamm Res. 2019;68:981-992 pubmed publisher
Yang Q, Yang K, Li Z. MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway. Kaohsiung J Med Sci. 2019;: pubmed publisher
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, et al. The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro. Front Physiol. 2019;10:1060 pubmed publisher
Wu Z, Wang J. Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice. Exp Lung Res. 2019;:1-9 pubmed publisher
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, et al. Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis. Pharmacol Res. 2019;148:104414 pubmed publisher
He S, Yu Q, He Y, Hu R, Xia S, He J. Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers. Poult Sci. 2019;: pubmed publisher
Xu Y, Wang X, Guo B, Wang D, KALVAKOLANU D, Chen X, et al. Nonviral delivery of GRIM-19 gene inhibits tumor growth with reduced local and systemic complications. Hum Gene Ther. 2019;: pubmed publisher
Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, et al. Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway. Int Immunopharmacol. 2019;75:105768 pubmed publisher
Sun L, Qiao W, Xiao Y, Cui L, Wang X, Ren W. Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway. Int Immunopharmacol. 2019;75:105782 pubmed publisher
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, et al. Response of the maternal hypothalamus to cold stress during late pregnancy in rats. Brain Res. 2019;1722:146354 pubmed publisher
Zhao J, Cao J, Yu L, Ma H. Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages. Mol Immunol. 2019;114:114-122 pubmed publisher
Zang Y, Chen D, Zhou B, Chen A, Wang J, Gao X, et al. FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation. Vascul Pharmacol. 2019;:106579 pubmed publisher
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, et al. Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer. Mol Cancer Res. 2019;: pubmed publisher
Doudou N, Kampo S, Liu Y, Ahmmed B, Zeng D, Zheng M, et al. Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values. Front Physiol. 2019;10:708 pubmed publisher
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product information
CatalogNo :
10745-1-AP
AntigenName :
NF-κB p65
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Immunogen :
Recombinant Protein
Species :
a. sphaerocephala krasch, chicken, cow, dog, hamster, hamsters, human, mouse, pig, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
NF Kappa B, NFKB 3, NFKB p65, NFKB3, NF-κB3, p65, RELA, Transcription factor p65
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC011603
Category :
Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Immunology;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:100 ; IHC 1:100 ; IP 1:1000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.