This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Ferritin light chain
catalog :
10727-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 22
Reference
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, et al. Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload. Cell Death Dis. 2020;11:574 pubmed publisher
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, et al. Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy. BMC Cancer. 2020;20:665 pubmed publisher
Li S, Qian Z, Xu G, Zheng J, Wu Y. Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron. Biosci Rep. 2020;40: pubmed publisher
Sheng Y, Chen Y, Qian Z, Zheng J, Liu Y. Cyclophosphamide induces a significant increase in iron content in the liver and spleen of mice. Hum Exp Toxicol. 2020;39:973-983 pubmed publisher
Chen Y, Qian Z, Sheng Y, Zheng J, Liu Y. Angiotensin II down-regulates transferrin receptor 1 and ferroportin 1 expression in Neuro-2a cells via activation of type-1 receptor. Neurosci Lett. 2020;716:134684 pubmed publisher
Zhu G, Kong J, Fu X, Liu F, Huang H, Hong L, et al. Identification of differentially expressed proteins associated with recurrence in ovarian endometriotic cysts. Syst Biol Reprod Med. 2019;:1-11 pubmed publisher
Gao W, Wang W, Liu G, Zhang J, Yang J, Deng Z. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome. Metab Brain Dis. 2019;34:319-329 pubmed publisher
Mercadante C, Prajapati M, Parmar J, Conboy H, Dash M, Pettiglio M, et al. Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess. Haematologica. 2019;104:678-689 pubmed publisher
Zhang M, Yang G, Zhou Y, Qian C, Mu M, Ke Y, et al. Regulating ferroportin-1 and transferrin receptor-1 expression: A novel function of hydrogen sulfide. J Cell Physiol. 2019;234:3158-3169 pubmed publisher
Zhang M, Zhao P, Yung W, Sheng Y, Ke Y, Qian Z. Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice. Aging (Albany NY). 2018;10:3834-3850 pubmed publisher
Huang T, Sun Y, Li Y, Wang T, Fu Y, Li C, et al. Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation. Oxid Med Cell Longev. 2018;2018:4928703 pubmed publisher
Niu L, Ye C, Sun Y, Peng T, Yang S, Wang W, et al. Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington's disease. Cell Biosci. 2018;8:41 pubmed publisher
Ma J, Zhang F, Zhou G, Bao Y, Shen Y, Qian Z. Different Characteristics of Hepcidin Expression in IL-6+/+ and IL-6-/- Neurons and Astrocytes Treated with Lipopolysaccharides. Neurochem Res. 2018;43:1624-1630 pubmed publisher
Huang S, Ruan H, Chen M, Zhou G, Qian Z. Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the JAK/STAT3 pathway in interleukin 6-treated PC-12 cells. Neurosci Lett. 2018;662:1-5 pubmed publisher
Luo Q, Zhou Y, Chen M, Liu L, Ma J, Zhang M, et al. Fasting up-regulates ferroportin 1 expression via a Ghrelin/GHSR/MAPK signaling pathway. J Cell Physiol. 2018;233:30-37 pubmed publisher
Zhou Y, Zhang C, Yang G, Qian Z, Zhang M, Ma J, et al. Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron. Front Physiol. 2017;8:332 pubmed publisher
Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner H, Lassmann H. Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. Brain. 2017;140:1900-1913 pubmed publisher
Zhuo Z, Fang S, Hu Q, Huang D, Feng J. Digital gene expression profiling analysis of duodenum transcriptomes in SD rats administered ferrous sulfate or ferrous glycine chelate by gavage. Sci Rep. 2016;6:37923 pubmed publisher
Zhang Y, Li F, Guo Y, Jiang L, Ma J, Ke Y, et al. (Z)-ligustilide increases ferroportin1 expression and ferritin content in ischemic SH-SY5Y cells. Eur J Pharmacol. 2016;792:48-53 pubmed publisher
Xue D, Zhou C, Shi Y, Lu H, Xu R, He X. Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin. Oncotarget. 2016;7:78804-78812 pubmed publisher
Pettiglio M, Herrera C, Foster M, Dorman D, Bartnikas T. Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure. Data Brief. 2016;6:989-97 pubmed publisher
Xu Y, Du F, Jiang L, Gong J, Zhou Y, Luo Q, et al. Effects of aspirin on expression of iron transport and storage proteins in BV-2 microglial cells. Neurochem Int. 2015;91:72-7 pubmed publisher
product information
CatalogNo :
10727-1-AP
AntigenName :
Ferritin light chain
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
ferritin, light polypeptide
Immunogen :
Recombinant Protein
Species :
human, monkey, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Ferritin L subunit, Ferritin light chain, ferritin, light polypeptide, FTL
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC008439
Category :
Binding Proteins;Disease Related;Membrane Proteins;Metabolism;Plasma/Serum;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:1000 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.