This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
KMO
catalog :
10698-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 3b
Wang B, Lian Y, Su W, Liu L, Li J, Jiang C, et al. Fr‑HMGB1 and ds‑HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive‑like behavior. Mol Med Rep. 2019;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
Korstanje R, Deutsch K, Bolanos Palmieri P, Hanke N, Schroder P, Staggs L, et al. Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria. J Am Soc Nephrol. 2016;27:3271-3277 pubmed
Chiu Y, Lei H, Huang K, Chiang Y, Lin C. Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors. J Oncol. 2019;2019:6201764 pubmed publisher
Xu G, Liu X, Wang Y. The cerebral protective effect and mechanism of action of vitamin B6 adjuvant ceftriaxone in experimental pneumococcal meningitis. Brain Res. 2018;1695:53-64 pubmed publisher
Hu P, Hunt N, Arfuso F, Shaw L, Uddin M, Zhu M, et al. Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Müller Cells of Diabetic Human and Rodent Retina. Invest Ophthalmol Vis Sci. 2017;58:5043-5055 pubmed publisher
Laumet G, Zhou W, Dantzer R, Edralin J, Huo X, Budac D, et al. Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain. Brain Behav Immun. 2017;66:94-102 pubmed publisher
Formisano S, Hornig M, Yaddanapudi K, Vasishtha M, Parsons L, Briese T, et al. Central Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid Production. J Virol. 2017;91: pubmed publisher
Guastella A, Michelhaugh S, Klinger N, Kupsky W, Polin L, Muzik O, et al. Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma. Mol Imaging. 2016;15: pubmed publisher
Rojewska E, Piotrowska A, Makuch W, Przewlocka B, Mika J. Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model. Neuropharmacology. 2016;102:80-91 pubmed publisher
product information
CatalogNo :
10698-1-AP
AntigenName :
KMO
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
KMO, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC005297
Category :
Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:25 ; IHC 1:200 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.