This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SPHK1
catalog :
10670-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Reference
Shen Z, Feng X, Fang Y, Li Y, Li Z, Zhan Y, et al. POTEE drives colorectal cancer development via regulating SPHK1/p65 signaling. Cell Death Dis. 2019;10:863 pubmed publisher
Xiao J, Lin H, Liu B, Xia Z, Zhang J, Jin J. Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury. Biomark Med. 2019;13:627-637 pubmed publisher
Qiang G, Wang Z, Ji A, Wu J, Cao Y, Zhang G, et al. Sphingosine kinase 1 knockout alleviates hepatic ischemia/reperfusion injury by attenuating inflammation and oxidative stress in mice. Hepatobiliary Pancreat Dis Int. 2019;18:255-265 pubmed publisher
Liu S, Xu C, Wu W, Fu Z, He S, Qin M, et al. Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis. Int J Oncol. 2019;54:41-52 pubmed publisher
Qiu Z, Yuan H, Li N, Yang X, Hu X, Su F, et al. Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages. Mol Med Rep. 2018;18:5399-5408 pubmed publisher
Pang H, Yue S, Tang Y, Chen Y, Tan Y, Cao Y, et al. Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia. Front Pharmacol. 2018;9:165 pubmed publisher
Xu C, Liu S, Qin M, Zhuge C, Qin L, Qin N, et al. SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells. Int J Mol Med. 2017;39:1277-1284 pubmed publisher
Liu X, Ren K, Suo R, Xiong S, Zhang Q, Mo Z, et al. ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. J Physiol Biochem. 2016;72:657-667 pubmed
Lu Z, Zhang W, Gao S, Jiang Q, Xiao Z, Ye L, et al. MiR-506 suppresses liver cancer angiogenesis through targeting sphingosine kinase 1 (SPHK1) mRNA. Biochem Biophys Res Commun. 2015;468:8-13 pubmed publisher
Lu Z, Xiao Z, Liu F, Cui M, Li W, Yang Z, et al. Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1). Oncotarget. 2016;7:241-54 pubmed publisher
Lu Z, Xiao Z, Yang Z, Li J, Feng G, Chen F, et al. Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1. Acta Pharmacol Sin. 2015;36:1228-36 pubmed publisher
product information
CatalogNo :
10670-1-AP
AntigenName :
SPHK1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sphingosine kinase 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
SK 1, sphingosine kinase 1, SPHK, SPHK1, SPHK1 phopho, SPK, SPK 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC008040
Category :
Apoptosis;Binding Proteins;Cell Cycle;Membrane Proteins;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:300 ; WB 1:300 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.