This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
HEY2
catalog :
10597-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6j
Quilichini E, Fabre M, Dirami T, Stedman A, De Vas M, Ozguc O, et al. Pancreatic ductal deletion of Hnf1b disrupts exocrine homeostasis, leads to pancreatitis and facilitates tumorigenesis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed publisher
Moon E, Kim Y, Vu P, Yoo H, Hong K, Lee Y, et al. TMEM100 is a key factor for specification of lymphatic endothelial progenitors. Angiogenesis. 2020;23:339-355 pubmed publisher
Long J, Wang X, Du X, Pan H, Wang J, Li Z, et al. JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix. Arthritis Res Ther. 2019;21:213 pubmed publisher
Tang C, Luo C, Hua Y, Zhou K, Duan H, Ma F, et al. Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention. PLoS ONE. 2019;14:e0214873 pubmed publisher
Churko J, Garg P, Treutlein B, Venkatasubramanian M, Wu H, Lee J, et al. Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. Nat Commun. 2018;9:4906 pubmed publisher
Zong D, Li J, Cai S, He S, Liu Q, Jiang J, et al. Notch1 regulates endothelial apoptosis via the ERK pathway in chronic obstructive pulmonary disease. Am J Physiol Cell Physiol. 2018;315:C330-C340 pubmed publisher
Qiu G, Mao X, Ma Y, Gao X, Wang Z, Jin M, et al. Ubiquitin-specific protease 22 acts as an oncoprotein to maintain glioma malignancy through deubiquitinating B cell-specific Moloney murine leukemia virus integration site 1 for stabilization. Cancer Sci. 2018;109:2199-2210 pubmed publisher
Tang C, Deng Y, Duan H, Zhang Y, Li Y, Qiu D, et al. The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice. J Appl Toxicol. 2018;38:834-842 pubmed publisher
Li W, Zhou J, Chen Y, Zhang G, Jiang P, Hong L, et al. Cigarette smoke enhances initiation and progression of lung cancer by mutating Notch1/2 and dysregulating downstream signaling molecules. Oncotarget. 2017;8:115128-115139 pubmed publisher
Kim T, Jeong J, Park J, Kim S, Heo J, Kang H, et al. miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3. Oncotarget. 2017;8:72788-72800 pubmed publisher
Jeong J, Kang H, Kim T, Kim G, Heo J, Kwon A, et al. MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3. Cancer Lett. 2017;386:168-178 pubmed publisher
Wu L, Wang J, Conidi A, Zhao C, Wang H, Ford Z, et al. Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination. Nat Neurosci. 2016;19:1060-72 pubmed publisher
Fujita M, Sakabe M, Ioka T, Watanabe Y, Kinugasa Katayama Y, Tsuchihashi T, et al. Pharyngeal arch artery defects and lethal malformations of the aortic arch and its branches in mice deficient for the Hrt1/Hey1 transcription factor. Mech Dev. 2016;139:65-73 pubmed publisher
Xie H, Sun J, Chen Y, Zong M, Li S, Wang Y. EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway. Oxid Med Cell Longev. 2015;2015:214836 pubmed publisher
Kang H, Jeong J, Song J, Kim T, Kim G, Huh J, et al. Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells. Mol Carcinog. 2016;55:1196-209 pubmed publisher
Mu X, Liao X, Chen X, Li Y, Wang M, Shen C, et al. DEHP exposure impairs mouse oocyte cyst breakdown and primordial follicle assembly through estrogen receptor-dependent and independent mechanisms. J Hazard Mater. 2015;298:232-40 pubmed publisher
product information
CatalogNo :
10597-1-AP
AntigenName :
HEY2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
hairy/enhancer-of-split related with YRPW motif 2
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
bHLHb32, CHF1, GRIDLOCK, GRL, hCHF1, HERP, HERP1, HESR 2, HESR2, HEY2, hHRT2, HRT 2, HRT2, Protein gridlock homolog
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC007707
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:100 ; IP 1:500 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.