This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MMP1
catalog :
10371-2-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 53
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 2d
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3c
Xie X, Wang Y, Xia Y, Mao Y. Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation. Biosci Rep. 2019;39: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7c
Liu X, Zhou Z, Li W, Zhang S, Li J, Zhou M, et al. Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis. Front Oncol. 2019;9:216 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5a
Nakamura D, Hollander J, Uchimura T, Nielsen H, Zeng L. Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions. BMC Musculoskelet Disord. 2017;18:39 pubmed publisher
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, et al. Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression. Biomed Pharmacother. 2020;127:110132 pubmed publisher
Schoenenberger A, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, et al. Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo. Biomaterials. 2020;249:120034 pubmed publisher
Sun L, Qu L, Brigstock D, Li H, Li Y, Gao R. Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line. Int J Med Sci. 2020;17:137-144 pubmed publisher
Wang Y, Ding X, Liu B, Li M, Chang Y, Shen H, et al. ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally. Mol Carcinog. 2020;59:73-86 pubmed publisher
Yao H, Wei S, Xiang Y, Wu Z, Liu W, Wang B, et al. Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway. Evid Based Complement Alternat Med. 2019;2019:5124026 pubmed publisher
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W. 25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4. Am J Cancer Res. 2019;9:2140-2155 pubmed
Tomko N, Kluever M, Wu C, Zhu J, Wang Y, Salomon R. 4-Hydroxy-7-oxo-5-heptenoic acid lactone is a potent inducer of brain cancer cell invasiveness that may contribute to the failure of anti-angiogenic therapies. Free Radic Biol Med. 2019;: pubmed publisher
Liang S, Wang Z, Zhang Z, Chen K, Lv Z, Wang Y, et al. Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop. Aging (Albany NY). 2019;11:8664-8680 pubmed publisher
Ma Y, Tu C, Liu W, Xiao Y, Wu H. Isorhapontigenin Suppresses Interleukin-1β-Induced Inflammation and Cartilage Matrix Damage in Rat Chondrocytes. Inflammation. 2019;42:2278-2285 pubmed publisher
Dias H, de Oliveira J, Donadio M, Kimura S. Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts. PLoS ONE. 2019;14:e0222202 pubmed publisher
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q. Induction of Fibroblast Senescence During Mouse Corneal Wound Healing. Invest Ophthalmol Vis Sci. 2019;60:3669-3679 pubmed publisher
Huang X, Ni B, Mao Z, Xi Y, Chu X, Zhang R, et al. NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway. J Cell Mol Med. 2019;: pubmed publisher
Cecen B, Keles D, Oktay G, Kozaci L. Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells. Chem Biol Interact. 2019;310:108730 pubmed publisher
Sun F, Hu P, Xiong Y, Bao J, Qian J, Wu L. Tricetin Protects Rat Chondrocytes against IL-1β-Induced Inflammation and Apoptosis. Oxid Med Cell Longev. 2019;2019:4695381 pubmed publisher
Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, et al. Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways. Eur J Pharmacol. 2019;:172481 pubmed publisher
Tu C, Ma Y, Song M, Yan J, Xiao Y, Wu H. Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes. Eur J Pharmacol. 2019;858:172445 pubmed publisher
Ita M, Winkelstein B. Concentration dependent effects of fibroblast-like synoviocytes on collagen gel multiscale biomechanics & neuronal signaling: Implications for modeling human ligamentous tissues. J Biomech Eng. 2019;: pubmed publisher
Zhao T, Chen H, Xu F, Wang J, Liu Y, Xing X, et al. Liraglutide alleviates cardiac fibrosis through inhibiting P4hα-1 expression in STZ-induced diabetic cardiomyopathy. Acta Biochim Biophys Sin (Shanghai). 2019;51:293-300 pubmed publisher
Yu H, Zeng R, Lin Y, Li X, Tasneem S, Yang Z, et al. Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats. Phytomedicine. 2019;58:152876 pubmed publisher
Tu C, Huang X, Xiao Y, Song M, Ma Y, Yan J, et al. Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes. Front Pharmacol. 2019;10:41 pubmed publisher
Li X, Xue Y, Liu X, Zheng J, Shen S, Yang C, et al. ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma. J Exp Clin Cancer Res. 2019;38:68 pubmed publisher
Wang S, Yao Y, Rao C, Zheng G, Chen W. 25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway. Int J Oncol. 2019;54:966-980 pubmed publisher
Zhang T, Li Q, Wang L, Li G. Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity. Exp Ther Med. 2019;17:181-186 pubmed publisher
Shi C, Wu L, Lin W, Cai Y, Zhang Y, Hu B, et al. MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus. Gene. 2019;687:156-165 pubmed publisher
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, et al. Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy. Arch Biochem Biophys. 2018;657:31-40 pubmed publisher
Jayatilaka H, Umanzor F, Shah V, Meirson T, Russo G, Starich B, et al. Tumor cell density regulates matrix metalloproteinases for enhanced migration. Oncotarget. 2018;9:32556-32569 pubmed publisher
He X, Shi L, Qiu M, Li Q, Wang M, Xiong Z, et al. Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families. Biochem Biophys Res Commun. 2018;504:878-884 pubmed publisher
Huang X, Xi Y, Pan Q, Mao Z, Zhang R, Ma X, et al. Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes. Biomed Pharmacother. 2018;107:433-439 pubmed publisher
Huang X, Pan Q, Mao Z, Wang P, Zhang R, Ma X, et al. Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways. Mol Med Rep. 2018;18:2697-2704 pubmed publisher
Li J, Yin H, Guan D, Zhao J, Feng Y, Deng Y, et al. Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis. Br J Cancer. 2018;118:1337-1348 pubmed publisher
Wang S, Ye L, Li M, Zhan H, Ye R, Li Y, et al. Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model. Angle Orthod. 2018;88:624-631 pubmed publisher
Wei S, Cao D, Xu X, Bai H, Wu H, Wang M. Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation. Mol Med Rep. 2018;17:6909-6913 pubmed publisher
Zhang H, Lai S, Huang L, Zhang Z, Liu J, Zheng S, et al. Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer. Gynecol Oncol. 2018;149:188-197 pubmed publisher
Rao Z, Wang S, Wang J. Protective effects of psoralidin on IL?1??induced chondrocyte apoptosis. Mol Med Rep. 2018;17:3418-3424 pubmed publisher
Huang X, Pan Q, Mao Z, Zhang R, Ma X, Xi Y, et al. Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes. Inflammation. 2018;41:562-568 pubmed publisher
Zheng X, Liu W, Xiang J, Liu P, Ke M, Wang B, et al. Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin ?1/FAK signaling pathway in nonalcoholic fatty liver. Oncotarget. 2017;8:95586-95595 pubmed publisher
Chen L, Li Q, Wang J, Jin S, Zheng H, Lin J, et al. MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN. J Cell Mol Med. 2017;21:3347-3359 pubmed publisher
Chiu H, Chen C, Chen Y, Hsu Y. Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice. PLoS ONE. 2017;12:e0174042 pubmed publisher
Zhao S, Zhao Y, Guo J, Fei C, Zheng Q, Li X, et al. Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation. Sci Rep. 2017;7:43849 pubmed publisher
Zeng L, Xiao C, Deng Z, Li R. Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model. Evid Based Complement Alternat Med. 2017;2017:8985623 pubmed publisher
Wang D, Wang D, Wang N, Long Z, Ren X. Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway. Cell Physiol Biochem. 2016;40:644-656 pubmed
Zhuang K, Zhang J, Xiong M, Wang X, Luo X, Han L, et al. CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis. Cell Death Dis. 2016;7:e2415 pubmed publisher
Li F, Fang Z, Zhang J, Li C, Liu H, Xia J, et al. Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma. Cell Res. 2016;26:1149-1164 pubmed publisher
Weiss G, Sundl M, Glasner A, Huppertz B, Moser G. The trophoblast plug during early pregnancy: a deeper insight. Histochem Cell Biol. 2016;146:749-756 pubmed publisher
Hu B, Shi C, Xu C, Cao P, Tian Y, Zhang Y, et al. Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration. Sci Rep. 2016;6:21190 pubmed publisher
Hong J, Liu R, Chen L, Wu B, Yu J, Gao W, et al. Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice. Thromb Res. 2016;137:148-156 pubmed publisher
Li T, Niu L, Li M, Liu Y, Xu Z, Gao X, et al. Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells. Mol Med Rep. 2015;12:3972-3978 pubmed publisher
Kmiecik A, Pula B, Suchanski J, Olbromski M, Gomulkiewicz A, Owczarek T, et al. Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression. PLoS ONE. 2015;10:e0124865 pubmed publisher
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher
product information
CatalogNo :
10371-2-AP
AntigenName :
MMP1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
matrix metallopeptidase 1 (interstitial collagenase)
Immunogen :
Recombinant Protein
Species :
human, mouse, rabbit, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CLG, CLGN, Fibroblast collagenase, Interstitial collagenase, Matrix metalloproteinase 1, MMP 1, MMP1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC013875
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.