This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PAX8
catalog :
10336-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 151
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3a
Diaz Osterman C, Ozmadenci D, Kleinschmidt E, Taylor K, Barrie A, Jiang S, et al. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. elife. 2019;8: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b
Low J, Li P, Chew E, Zhou B, Suzuki K, Zhang T, et al. Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. Cell Stem Cell. 2019;25:373-387.e9 pubmed publisher
Drake K, Chaney C, Das A, Roy P, Kwartler C, Rakheja D, et al. Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development. 2020;: pubmed publisher
Choi P, So W, Yang J, Liu S, Tong K, Kwan K, et al. MicroRNA-200 family governs ovarian inclusion cyst formation and mode of ovarian cancer spread. Oncogene. 2020;39:4045-4060 pubmed publisher
Moyano Galceran L, Pietilä E, Turunen S, Corvigno S, Hjerpe E, Bulanova D, et al. Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer. EMBO Mol Med. 2020;12:e11177 pubmed publisher
Hoffmann K, Berger H, Kulbe H, Thillainadarasan S, Mollenkopf H, Zemojtel T, et al. Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment. EMBO J. 2020;39:e104013 pubmed publisher
Lavin V, Callipo F, Donofrio C, Ellwood Thompson R, Metcalf R, Djoukhadar I, et al. Primary epithelial-myoepithelial carcinoma of the pituitary gland. Neuropathology. 2020;: pubmed publisher
Syed S, Kumar M, Ghosh A, Tomasetig F, Ali A, Whan R, et al. Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation. Cell Stem Cell. 2020;26:64-80.e13 pubmed publisher
Ye H, Qin S, Li N, Lin M, Xu Y, Li X. A Rare Partner of TFE3 in the Xp11 Translocation Renal Cell Carcinoma: Clinicopathological Analyses and Detection of MED15-TFE3 Fusion. Biomed Res Int. 2019;2019:5974089 pubmed publisher
Zhang S, Dolgalev I, Zhang T, Ran H, Levine D, Neel B. Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma. Nat Commun. 2019;10:5367 pubmed publisher
Legesse T, Matoso A, Epstein J. PAX8 positivity in nested variant of urothelial carcinoma: a potential diagnostic pitfall. Hum Pathol. 2019;94:11-15 pubmed publisher
De Clercq K, Xie F, De Wever O, Descamps B, Hoorens A, Vermeulen A, et al. Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer. Sci Rep. 2019;9:14881 pubmed publisher
Tsuzuki S, Kataoka T, Ito H, Ueshima C, Asai S, Yokoo H, et al. A case of renal cell carcinoma unclassified with medullary phenotype without detectable gene deletion. Pathol Int. 2019;: pubmed publisher
Li M, Dong C, Sun B, Lei H, Wang Y, Gong Y, et al. LncRNA-MALAT1 promotes tumorogenesis of infantile hemangioma by competitively binding miR-424 to stimulate MEKK3/NF-κB pathway. Life Sci. 2019;239:116946 pubmed publisher
Bennett J, Ritterhouse L, Furtado L, Lastra R, Pesci A, Newell J, et al. Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases. Mod Pathol. 2019;: pubmed publisher
St Jean G, Tsoi M, Abedini A, Levasseur A, Rico C, Morin M, et al. Lats1 and Lats2 are required for the maintenance of multipotency in the Müllerian duct mesenchyme. Development. 2019;146: pubmed publisher
Mori Y, Yamawaki K, Ishiguro T, Yoshihara K, Ueda H, Sato A, et al. ALDH-Dependent Glycolytic Activation Mediates Stemness and Paclitaxel Resistance in Patient-Derived Spheroid Models of Uterine Endometrial Cancer. Stem Cell Reports. 2019;13:730-746 pubmed publisher
Wang X, Fang R, Ye S, Zhang R, Li R, Wang X, et al. Targeted next-generation sequencing revealed distinct clinicopathologic and molecular features of VCL-ALK RCC: A unique case from an older patient without clinical evidence of sickle cell trait. Pathol Res Pract. 2019;215:152651 pubmed publisher
Rockfield S, Kee Y, Nanjundan M. Chronic iron exposure and c-Myc/H-ras-mediated transformation in fallopian tube cells alter the expression of EVI1, amplified at 3q26.2 in ovarian cancer. Oncogenesis. 2019;8:46 pubmed publisher
Qi C, Xiaofeng C, Dongen L, Liang Y, Liping X, Yue H, et al. Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/NOTCH1 signaling pathway. J Exp Clin Cancer Res. 2019;38:344 pubmed publisher
Saglietti C, Schneider V, Bongiovanni M, Missiaglia E, Bisig B, Dorta G, et al. Acinar cell carcinoma of the pancreas with thyroid-like follicular features: first description of a new diagnostic challenging subtype. Virchows Arch. 2019;: pubmed publisher
Nikitski A, Rominski S, Condello V, Kaya C, Wankhede M, Panebianco F, et al. Mouse Model of Thyroid Cancer Progression and Dedifferentiation Driven by STRN-ALK Expression and Loss of p53: Evidence for the Existence of Two Types of Poorly Differentiated Carcinoma. Thyroid. 2019;: pubmed publisher
Yang B, Duan H, Cao W, Guo Y, Liu Y, Sun L, et al. Xp11 translocation renal cell carcinoma and clear cell renal cell carcinoma with TFE3 strong positive immunostaining: morphology, immunohistochemistry, and FISH analysis. Mod Pathol. 2019;: pubmed publisher
Baldwin P, Ohman A, Medina J, McCarthy E, Dinulescu D, Sridhar S. Nanoformulation of Talazoparib Delays Tumor Progression and Ascites Formation in a Late Stage Cancer Model. Front Oncol. 2019;9:353 pubmed publisher
Shen Y, Wang L, Evans J, Allen C, Piquette Miller M. Development of a Bioluminescent BRCA1-Deficient Xenograft Model of Disseminated, High-Grade Serous Ovarian Cancer. Int J Mol Sci. 2019;20: pubmed publisher
Sowamber R, Chehade R, Bitar M, Dodds L, Milea A, Slomovitz B, et al. CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma. EBioMedicine. 2019;: pubmed publisher
Kopper O, de Witte C, Lõhmussaar K, Valle Inclan J, Hami N, Kester L, et al. An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity. Nat Med. 2019;25:838-849 pubmed publisher
Xing D, Zheng G, Pallavajjala A, Schoolmeester J, Liu Y, Haley L, et al. Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics. Clin Cancer Res. 2019;: pubmed publisher
Suster D, Ronen S, Peterson J, MacKinnon A, Hes O, Suster S, et al. MDM2 amplification and immunohistochemical expression in sarcomatoid renal cell carcinoma. Hum Pathol. 2019;: pubmed publisher
Phan N, Hong J, Tofig B, Mapua M, Elashoff D, Moatamed N, et al. A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids. Commun Biol. 2019;2:78 pubmed publisher
Sun H, Fukuda S, Hirata T, Arakawa T, Ma S, Neriishi K, et al. IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis. Reprod Sci. 2019;:1933719119831782 pubmed publisher
Garreta E, Prado P, Tarantino C, Oria R, Fanlo L, Marti E, et al. Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells. Nat Mater. 2019;18:397-405 pubmed publisher
Arakawa T, Fukuda S, Hirata T, Neriishi K, Wang Y, Takeuchi A, et al. PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis. Reprod Sci. 2019;:1933719119828095 pubmed publisher
Wyvekens N, Rechsteiner M, Fritz C, Wagner U, Tchinda J, Wenzel C, et al. Histological and molecular characterization of TFEB-rearranged renal cell carcinomas. Virchows Arch. 2019;474:625-631 pubmed publisher
Chen Y, Mirsadraei L, Jayakumaran G, Al Ahmadie H, Fine S, Gopalan A, et al. Somatic Mutations of TSC2 or MTOR Characterize a Morphologically Distinct Subset of Sporadic Renal Cell Carcinoma With Eosinophilic and Vacuolated Cytoplasm. Am J Surg Pathol. 2019;43:121-131 pubmed publisher
Stolnicu S, Hoang L, Hankó Bauer O, Barsan I, Terinte C, Pesci A, et al. Cervical adenosquamous carcinoma: detailed analysis of morphology, immunohistochemical profile, and clinical outcomes in 59 cases. Mod Pathol. 2019;32:269-279 pubmed publisher
Nakamura A, Yamaguchi K, Minamiguchi S, Murakami R, Abiko K, Hamanishi J, et al. Mucinous adenocarcinoma, gastric type of the uterine cervix: clinical features and HER2 amplification. Med Mol Morphol. 2019;52:52-59 pubmed publisher
Collins G, Mesiano S, Difeo A. Effects of Metformin on Cellular Proliferation and Steroid Hormone Receptors in Patient-Derived, Low-Grade Endometrial Cancer Cell Lines. Reprod Sci. 2019;26:609-618 pubmed publisher
McHugh K, Arrossi A, Farver C, Mukhopadhyay S. Does Strong and Diffuse PAX-8 Positivity Occur in Primary Lung Carcinoma? An Immunohistochemical Study of 418 Cases and Review of the Literature. Appl Immunohistochem Mol Morphol. 2019;27:140-146 pubmed publisher
Wheeler L, Watson Z, Qamar L, Yamamoto T, Post M, Berning A, et al. CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer. Oncogenesis. 2018;7:92 pubmed publisher
Munakata S, Tomiyama E, Takayama H. Case Report of Atypical Juxtaglomerular Cell Tumor. Case Rep Pathol. 2018;2018:6407360 pubmed publisher
Tsuji H, Yasuoka H, Nakamura Y, Hirokawa M, Hiroshima T, Sakamaki Y, et al. Aggressive cribriform-morular variant of papillary thyroid carcinoma: Report of an unusual case with pulmonary metastasis displaying poorly differentiated features. Pathol Int. 2018;68:700-705 pubmed publisher
Kondrashova O, Topp M, Nesic K, Lieschke E, Ho G, Harrell M, et al. Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. Nat Commun. 2018;9:3970 pubmed publisher
Xie Y, Park E, Xiang D, Li Z. Long-term organoid culture reveals enrichment of organoid-forming epithelial cells in the fimbrial portion of mouse fallopian tube. Stem Cell Res. 2018;32:51-60 pubmed publisher
Menon R, Otto E, Kokoruda A, Zhou J, Zhang Z, Yoon E, et al. Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney. Development. 2018;145: pubmed publisher
Jing H, Wei H, Yuan H, Li Y, Li N, Mu D. Melanotic Xp11 translocation renal cancer: a report of a distinctive case and a review of the literature. Diagn Pathol. 2018;13:51 pubmed publisher
Han X, Chen H, Zhou J, Steed H, Postovit L, Fu Y. Pharmacological Inhibition of p38 MAPK by SB203580 Increases Resistance to Carboplatin in A2780cp Cells and Promotes Growth in Primary Ovarian Cancer Cells. Int J Mol Sci. 2018;19: pubmed publisher
Suzuki T, Eng D, McClelland A, Pippin J, Shankland S. Cells of NG2 lineage increase in glomeruli of mice following podocyte depletion. Am J Physiol Renal Physiol. 2018;315:F1449-F1464 pubmed publisher
Iwadate M, Takizawa Y, Shirai Y, Kimura S. An in vivo model for thyroid regeneration and folliculogenesis. Lab Invest. 2018;98:1126-1132 pubmed publisher
Montecalvo J, Chang J, Rekhtman N, Antonescu C, Bains M, Fabbri N, et al. Type A Thymoma Presenting with Bone Metastasis. Histopathology. 2018;: pubmed publisher
Hollingsworth J, Lau A, Tone A, Kollara A, Allen L, Colgan T, et al. BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells. Neoplasia. 2018;20:697-709 pubmed publisher
Czerniecki S, CRUZ N, Harder J, Menon R, Annis J, Otto E, et al. High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping. Cell Stem Cell. 2018;22:929-940.e4 pubmed publisher
Gabbasov R, Xiao F, Howe C, Bickel L, O Brien S, Benrubi D, et al. NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice. Oncogene. 2018;37:4854-4870 pubmed publisher
Xiang L, Rong G, Zhao J, Wang Z, Shi F. Identification of candidate genes associated with tubal origin of high-grade serous ovarian cancer. Oncol Lett. 2018;15:7769-7775 pubmed publisher
Ramalingam H, Fessler A, Das A, Valerius M, Basta J, Robbins L, et al. Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018;440:13-21 pubmed publisher
Grimley E, Dressler G. Are Pax proteins potential therapeutic targets in kidney disease and cancer?. Kidney Int. 2018;94:259-267 pubmed publisher
Lupia M, Angiolini F, Bertalot G, Freddi S, SACHSENMEIER K, Chisci E, et al. CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells. Stem Cell Reports. 2018;10:1412-1425 pubmed publisher
Yasuoka H, Nakamura Y, Yoshida K, Shimo T, Tori M, Matsui Y, et al. A rare case of ectopic papillary thyroid carcinoma transformed into squamous cell carcinoma. Pathol Int. 2018;68:246-250 pubmed publisher
Kodaira M, Yonemori K, Shimoi T, Yoshida A, Yoshida M, Kitano A, et al. Prognostic impact of presumed breast or ovarian cancer among patients with unfavorable-subset cancer of unknown primary site. BMC Cancer. 2018;18:176 pubmed publisher
Dreaden E, Kong Y, Quadir M, Correa S, Suárez López L, Barberio A, et al. RNA-Peptide nanoplexes drug DNA damage pathways in high-grade serous ovarian tumors. Bioeng Transl Med. 2018;3:26-36 pubmed publisher
Itoh H, Mogami H, Bou Nemer L, Word L, Rogers D, MILLER R, et al. Endometrial stromal cell attachment and matrix homeostasis in abdominal wall endometriomas. Hum Reprod. 2018;33:280-291 pubmed publisher
Mathew D, Wang Y, Van Arsdale A, Horwitz S, McDaid H. Expression of βV-Tubulin in Secretory Cells of the Fallopian Tube Epithelium Marks Cellular Atypia. Int J Gynecol Cancer. 2018;28:363-370 pubmed publisher
Xing D, Banet N, Sharma R, Vang R, Ronnett B, Illei P. Aberrant Pax-8 expression in well-differentiated papillary mesothelioma and malignant mesothelioma of the peritoneum: a clinicopathologic study. Hum Pathol. 2018;72:160-166 pubmed publisher
Ma Q, Wang Y, Zhang T, Zuo W. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy. Life Sci. 2018;193:104-109 pubmed publisher
Park K, Patel P, Linkov I, Jotwani A, Kauff N, Pike M. Observations on the origin of ovarian cortical inclusion cysts in women undergoing risk-reducing salpingo-oophorectomy. Histopathology. 2018;72:766-776 pubmed publisher
Xia Q, Wang X, Ye S, Wang X, Li R, Shi S, et al. Novel gene fusion of PRCC-MITF defines a new member of MiT family translocation renal cell carcinoma: clinicopathological analysis and detection of the gene fusion by RNA sequencing and FISH. Histopathology. 2018;72:786-794 pubmed publisher
Tandon R, Jimenez Cortez Y, Taub R, Borczuk A. Immunohistochemistry in Peritoneal Mesothelioma: A Single-Center Experience of 244 Cases. Arch Pathol Lab Med. 2018;142:236-242 pubmed publisher
Adler E, Corona R, Lee J, Rodriguez Malave N, Mhawech Fauceglia P, Sowter H, et al. The PAX8 cistrome in epithelial ovarian cancer. Oncotarget. 2017;8:108316-108332 pubmed publisher
Gonçalves A, Adlesic M, Brandt S, Hejhal T, Harlander S, Sommer L, et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun. 2017;8:1466 pubmed publisher
Asano Y, Odagiri T, Oikiri H, Matsusaki M, Akashi M, Shimoda H. Construction of artificial human peritoneal tissue by cell-accumulation technique and its application for visualizing morphological dynamics of cancer peritoneal metastasis. Biochem Biophys Res Commun. 2017;494:213-219 pubmed publisher
Kim Y, Refaeli I, Brooks C, Jing P, Gulieva R, Hughes M, et al. Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development. Stem Cells. 2017;35:2366-2378 pubmed publisher
Farhat N, Onenerk A, Krane J, Dias Santagata D, Sadow P, Faquin W. Primary Benign and Malignant Thyroid Neoplasms With Signet Ring Cells: Cytologic, Histologic, and Molecular Features. Am J Clin Pathol. 2017;148:251-258 pubmed publisher
Basta J, Robbins L, Denner D, Kolar G, Rauchman M. A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation. Development. 2017;144:3080-3094 pubmed publisher
Ghosh A, Syed S, Tanwar P. In vivo genetic cell lineage tracing reveals that oviductal secretory cells self-renew and give rise to ciliated cells. Development. 2017;144:3031-3041 pubmed publisher
Sarkar S, Bristow C, Dey P, Rai K, Perets R, Ramirez Cardenas A, et al. PRKCI promotes immune suppression in ovarian cancer. Genes Dev. 2017;31:1109-1121 pubmed publisher
Hirokawa M, Miyauchi A, Kihara M, Kudo T, Hashimoto Y, Suzuki S, et al. Chromophobe renal cell carcinoma-like thyroid carcinoma: A novel clinicopathologic entity possibly associated with tuberous sclerosis complex. Endocr J. 2017;64:843-850 pubmed publisher
Kaku Y, Taguchi A, Tanigawa S, Haque F, Sakuma T, Yamamoto T, et al. PAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells. Sci Rep. 2017;7:4554 pubmed publisher
Hirsch M, Nascimento A. PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma. Case Rep Pathol. 2017;2017:6714549 pubmed publisher
Zhai Y, Wu R, Kuick R, Sessine M, Schulman S, Green M, et al. High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease. J Pathol. 2017;243:16-25 pubmed publisher
Yasuoka H, Nakamura Y, Hirokawa M, Yoshida K, Anno K, Tori M, et al. A rare case of poorly differentiated thyroid carcinoma probably arising from a nodular goiter. BMC Clin Pathol. 2017;17:9 pubmed publisher
Harlander S, Schönenberger D, Toussaint N, Prummer M, Catalano A, Brandt L, et al. Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice. Nat Med. 2017;23:869-877 pubmed publisher
Desmeules P, Joubert P, Zhang L, Al Ahmadie H, Fletcher C, Vakiani E, et al. A Subset of Malignant Mesotheliomas in Young Adults Are Associated With Recurrent EWSR1/FUS-ATF1 Fusions. Am J Surg Pathol. 2017;41:980-988 pubmed publisher
Havrilak J, Melton K, Shannon J. Endothelial cells are not required for specification of respiratory progenitors. Dev Biol. 2017;427:93-105 pubmed publisher
Trippel M, Imboden S, Papadia A, Mueller M, Mertineit N, Härmä K, et al. Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report. Diagn Pathol. 2017;12:39 pubmed publisher
Gu Y, Cohn S, Christie A, McKenzie T, Wolff N, Do Q, et al. Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade. Cancer Discov. 2017;7:900-917 pubmed publisher
Francavilla C, Lupia M, Tsafou K, Villa A, Kowalczyk K, Rakownikow Jersie Christensen R, et al. Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer. Cell Rep. 2017;18:3242-3256 pubmed publisher
Kojima F, Koike H, Matsuzaki I, Iwahashi Y, Warigaya K, Fujimoto M, et al. Macrocystic ductal adenocarcinoma of prostate: A rare gross appearance of prostate cancer. Ann Diagn Pathol. 2017;27:7-13 pubmed publisher
Basuli D, Tesfay L, Deng Z, Paul B, Yamamoto Y, Ning G, et al. Iron addiction: a novel therapeutic target in ovarian cancer. Oncogene. 2017;36:4089-4099 pubmed publisher
Wang X, Xia Q, Ni H, Ye S, Li R, Wang X, et al. SFPQ/PSF-TFE3 renal cell carcinoma: a clinicopathologic study emphasizing extended morphology and reviewing the differences between SFPQ-TFE3 RCC and the corresponding mesenchymal neoplasm despite an identical gene fusion. Hum Pathol. 2017;63:190-200 pubmed publisher
Polosukhina D, Love H, Correa H, Su Z, Dahlman K, Pao W, et al. Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors. Mol Oncol. 2017;11:405-421 pubmed publisher
Murata T, Iwadate M, Takizawa Y, Miyakoshi M, Hayase S, Yang W, et al. An Adult Mouse Thyroid Side Population Cell Line that Exhibits Enriched Epithelial-Mesenchymal Transition. Thyroid. 2017;27:460-474 pubmed publisher
Koperski Ł, Szczepankiewicz B, Pihowicz P, Fus Ł, Wolinska E, Gornicka B. Adrenal cyst with both Müllerian and mesothelial differentiation- a clinicopathological and immunohistochemical study with implications for histogenesis. Histol Histopathol. 2017;32:1141-1149 pubmed publisher
George E, Kim H, Krepler C, Wenz B, Makvandi M, Tanyi J, et al. A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers. JCI Insight. 2017;2:e89760 pubmed publisher
Morizane R, Bonventre J. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat Protoc. 2017;12:195-207 pubmed publisher
Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, et al. Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling. elife. 2016;5: pubmed publisher
Elias K, Emori M, Westerling T, Long H, Budina Kolomets A, Li F, et al. Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors. JCI Insight. 2016;1: pubmed
Liu Q, Jiang M, Kuang Y, Shu X, Li J, Li M, et al. Dicer1 Ablation Impairs Responsiveness of Cerebellar Granule Neuron Precursors to Sonic Hedgehog and Disrupts Expression of Distinct Cell Cycle Regulator Genes. Cerebellum. 2017;16:450-461 pubmed publisher
Nagendra P, Goad J, Nielsen S, Rassam L, Lombard J, Nahar P, et al. Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions. Oncotarget. 2016;7:64836-64853 pubmed publisher
Wu R, Zhai Y, Kuick R, Karnezis A, García P, Naseem A, et al. Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse. J Pathol. 2016;240:341-351 pubmed publisher
Hellner K, Miranda F, Fotso Chedom D, Herrero González S, Hayden D, Tearle R, et al. Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies. EBioMedicine. 2016;10:137-49 pubmed publisher
Yamazaki T, Sasaki S, Okamoto T, Sato Y, Hayashi A, Ariga T. Up-Regulation of CD74 Expression in Parietal Epithelial Cells in a Mouse Model of Focal Segmental Glomerulosclerosis. Nephron. 2016;134:238-252 pubmed
Lobo N, Gedye C, Apostoli A, Brown K, Paterson J, Stickle N, et al. Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine. BMC Cancer. 2016;16:485 pubmed publisher
Collini P, Barisella M, Renne S, Pizzi N, Mattavelli D, Stacchiotti S, et al. Epithelioid angiosarcoma of the thyroid gland without distant metastases at diagnosis: report of six cases with a long follow-up. Virchows Arch. 2016;469:223-32 pubmed publisher
Rodgers L, O Hainmhire E, Young A, Burdette J. Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium. Oncotarget. 2016;7:32785-95 pubmed publisher
Weissferdt A, Moran C. Neuroendocrine Differentiation in Thymic Carcinomas: A Diagnostic Pitfall: An Immunohistochemical Analysis of 27 Cases. Am J Clin Pathol. 2016;145:393-400 pubmed publisher
Lichtnekert J, Kaverina N, Eng D, Gross K, Kutz J, Pippin J, et al. Renin-Angiotensin-Aldosterone System Inhibition Increases Podocyte Derivation from Cells of Renin Lineage. J Am Soc Nephrol. 2016;27:3611-3627 pubmed
Bajwa P, Nagendra P, Nielsen S, Sahoo S, Bielanowicz A, Lombard J, et al. Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium. Oncotarget. 2016;7:19214-27 pubmed publisher
Cykowski M, Takei H, Baskin D, Rivera A, Powell S. Epithelial and organ-related marker expression in pituitary adenomas. Neuropathology. 2016;36:354-64 pubmed publisher
Kasajima A, Cameselle Teijeiro J, Loidi L, Takahashi Y, Nakashima N, Sato S, et al. A Calcitonin Non-producing Neuroendocrine Tumor of the Thyroid Gland. Endocr Pathol. 2016;27:325-331 pubmed
Hirokawa M, Miyauchi A, Otsuru M, Daa T. Malignant melanoma arising in melanin-producing medullary thyroid carcinoma. Int J Surg Case Rep. 2016;20:118-22 pubmed publisher
Wang X, Xia Q, Ni H, Wang Z, Ye S, Li R, et al. Xp11 neoplasm with melanocytic differentiation of the prostate harbouring the novel NONO-TFE3 gene fusion: report of a unique case expanding the gene fusion spectrum. Histopathology. 2016;69:450-8 pubmed publisher
Weissferdt A, Moran C. Ectopic primary intrathyroidal thymoma: a clinicopathological and immunohistochemical analysis of 3 cases. Hum Pathol. 2016;49:71-6 pubmed publisher
Kawai T, Tominaga S, Hiroi S, Ogata S, Nakanishi K, Kawahara K, et al. Peritoneal malignant mesothelioma (PMM), and primary peritoneal serous carcinoma (PPSC) and reactive mesothelial hyperplasia (RMH) of the peritoneum. Immunohistochemical and fluorescence in situ hybridisation (FISH) analyses. J Clin Pathol. 2016;69:706-12 pubmed publisher
Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, et al. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat Commun. 2015;6:8989 pubmed publisher
Fleury H, Communal L, Carmona E, Portelance L, Arcand S, Rahimi K, et al. Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease. Genes Cancer. 2015;6:378-398 pubmed
Kurmann A, Serra M, Hawkins F, Rankin S, Mori M, Astapova I, et al. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 2015;17:527-42 pubmed publisher
Prayson R. Metastatic chromophobe renal cell carcinoma to the brain. J Clin Neurosci. 2016;26:152-3 pubmed publisher
Zhao M, Rao Q, Wu C, Zhao Z, He X, Ru G. Alveolar soft part sarcoma of lung: report of a unique case with emphasis on diagnostic utility of molecular genetic analysis for TFE3 gene rearrangement and immunohistochemistry for TFE3 antigen expression. Diagn Pathol. 2015;10:160 pubmed publisher
Hua G, Lv X, He C, Remmenga S, Rodabough K, Dong J, et al. YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells. Oncogene. 2016;35:2247-65 pubmed publisher
Suzuki A, Hirokawa M, Takada N, Higuchi M, Yamao N, Kuma S, et al. Diagnostic significance of PAX8 in thyroid squamous cell carcinoma. Endocr J. 2015;62:991-5 pubmed publisher
Ichiyanagi O, Ito H, Takai S, Naito S, Kato T, Nagaoka A, et al. A GRIA2 and PAX8-positive renal solitary fibrous tumor with NAB2-STAT6 gene fusion. Diagn Pathol. 2015;10:155 pubmed publisher
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product information
CatalogNo :
10336-1-AP
AntigenName :
PAX8
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
paired box 8
Immunogen :
Recombinant Protein
Species :
bovine, human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
paired box 8, Paired box protein Pax 8, PAX8
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC001060
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Disease Related;IVD;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:1200 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.