This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
NUDT21
catalog :
10322-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 11
Reference
Alcott C, Yalamanchili H, Ji P, van der Heijden M, Saltzman A, Elrod N, et al. Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation. elife. 2020;9: pubmed publisher
Ko J, Mills T, Huang J, Chen N, Mertens T, Collum S, et al. Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis. J Biol Chem. 2019;294:15781-15794 pubmed publisher
Weng T, Ko J, Masamha C, Xia Z, Xiang Y, Chen N, et al. Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation. J Clin Invest. 2019;130: pubmed publisher
Chen S, Wang R, Zheng D, Zhang H, Chang X, Wang K, et al. The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export. Mol Cell. 2019;74:118-131.e7 pubmed publisher
Cheng Z, Miao D, Su Q, Tang X, Wang X, Deng L, et al. THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism. Acta Pharmacol Sin. 2019;40:814-822 pubmed publisher
Tellier M, Hardy J, Norbury C, Murphy S. Effect of CFIm25 knockout on RNA polymerase II transcription. BMC Res Notes. 2018;11:894 pubmed publisher
Huang J, Weng T, Ko J, Chen N, Xiang Y, Volcik K, et al. Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation. Biochem Biophys Res Commun. 2018;503:856-862 pubmed publisher
Movassat M, Crabb T, Busch A, Yao C, Reynolds D, Shi Y, et al. Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns. RNA Biol. 2016;13:646-55 pubmed publisher
Masamha C, Xia Z, Peart N, Collum S, Li W, Wagner E, et al. CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function. RNA. 2016;22:830-8 pubmed publisher
Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, et al. The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination. EMBO J. 2015;34:2885-902 pubmed publisher
Misra A, Ou J, Zhu L, Green M. Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors. Mol Cell. 2015;58:819-31 pubmed publisher
product information
CatalogNo :
10322-1-AP
AntigenName :
NUDT21
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
nudix (nucleoside diphosphate linked moiety X)-type motif 21
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ChIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CFIM25, CPSF 25 kDa subunit, CPSF25, CPSF5, Nudix motif 21, NUDT21
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC001403
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:100 ; IP 1:500 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.