This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Lamin A/C
catalog :
10298-1-AP
quantity :
150UL
price :
99 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 52
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed publisher
  • western blot; human; loading ...; fig s2a
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, et al. NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1. J Immunol. 2019;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4d
Zhu T, Yong X, Xia D, Widagdo J, Anggono V. Ubiquitination Regulates the Proteasomal Degradation and Nuclear Translocation of the Fat Mass and Obesity-Associated (FTO) Protein. J Mol Biol. 2018;430:363-371 pubmed publisher
  • western blot; human; loading ...; fig 5d
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed publisher
  • western blot; human; loading ...; fig 2a
Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, et al. Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation. Aging (Albany NY). 2020;12:13297-13317 pubmed publisher
Dharan A, Bachmann N, Talley S, Zwikelmaier V, Campbell E. Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus. Nat Microbiol. 2020;: pubmed publisher
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, et al. Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate. Exp Ther Med. 2020;19:2861-2870 pubmed publisher
Ma C, Xu W, Yang Q, Liu W, Xiang Q, Chen J, et al. Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication. J Virol. 2020;94: pubmed publisher
Wang S, Cheng H, Wang L, Zhao R, Guan D. Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes. Int J Mol Sci. 2020;21: pubmed publisher
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, et al. Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis. J Exp Clin Cancer Res. 2020;39:24 pubmed publisher
Cai B, Lee H, Chou C, Wu P, Huang H, Chao C, et al. SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells. Cells. 2020;9: pubmed publisher
Duan T, Jiao H, He G, Yan Y. Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN). Cells. 2020;9: pubmed publisher
Zhao Q, Li C, Yu M, Sun Y, Wang J, Ma L, et al. HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner. RNA Biol. 2020;17:500-516 pubmed publisher
Li K, Tao N, Zheng L, Sun T. LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung. Int Immunopharmacol. 2020;79:106057 pubmed publisher
Woods P, Kimmig L, Meliton A, Sun K, Tian Y, O Leary E, et al. Tissue Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
Feng X, Zhang M, Wang B, Zhou C, Mu Y, Li J, et al. CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status. J Exp Clin Cancer Res. 2019;38:361 pubmed publisher
Ling J, Dong X, Wang L, Xue Y, Jia X, Song W, et al. MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity. Am J Transl Res. 2019;11:3069-3080 pubmed
Xu L, Zhang T, Huang W, Liu X, Lu J, Gao X, et al. YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth. Acta Biochim Biophys Sin (Shanghai). 2019;51:677-687 pubmed publisher
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher
Zhao X, Wu Y, Li J, Li D, Jin Y, Zhu P, et al. JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation. Toxicology. 2019;423:42-53 pubmed publisher
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, et al. HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression. Biochim Biophys Acta Gene Regul Mech. 2019;: pubmed publisher
Zhang S, He K, Zhou W, Cao J, Jin Z. miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN. Mol Med Rep. 2019;19:4288-4296 pubmed publisher
Wu X, Wang J, Wang S, Wu F, Chen Z, Li C, et al. Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP. Front Microbiol. 2019;10:344 pubmed publisher
Cheng H, Qi T, Zhang X, Kong Q, Min X, Mao Q, et al. Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice. Biochim Biophys Acta Mol Basis Dis. 2019;1865:1451-1459 pubmed publisher
Yang J, Zhang X, Chen Z, Shen Y, Wang F, Wang Y, et al. Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer. Cell Death Dis. 2019;10:179 pubmed publisher
Han M, Zhao M, Cheng C, Huang Y, Han S, Li W, et al. Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation. Hum Mutat. 2019;40:310-325 pubmed publisher
Kong Q, Li N, Cheng H, Zhang X, Cao X, Qi T, et al. HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. Diabetes. 2019;68:361-376 pubmed publisher
Ma J, Li S, Zhu L, Guo S, Yi X, Cui T, et al. Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway. Free Radic Biol Med. 2018;129:492-503 pubmed publisher
Tan F, Huang Y, Pei Q, Liu H, Pei H, Zhu H. Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells. J Cell Biochem. 2018;: pubmed publisher
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, et al. Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction. Toxicol Sci. 2018;165:232-243 pubmed publisher
Yan B, Jiang Z, Cheng L, Chen K, Zhou C, Sun L, et al. Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1?. Exp Cell Res. 2018;371:63-71 pubmed publisher
Fang L, Teng H, Wang Y, Liao G, Weng L, Li Y, et al. SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis. Cancer Cell. 2018;34:103-118.e9 pubmed publisher
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, et al. Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1?. J Cell Mol Med. 2018;22:4507-4521 pubmed publisher
Wei X, Li X, Yan W, Zhang X, Sun Y, Zhang F. SKP2 Promotes Hepatocellular Carcinoma Progression Through Nuclear AMPK-SKP2-CARM1 Signaling Transcriptionally Regulating Nutrient-Deprived Autophagy Induction. Cell Physiol Biochem. 2018;47:2484-2497 pubmed publisher
Kumar S, Wang G, Liu W, Ding W, Dong M, Zheng N, et al. Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms. Hypertension. 2018;72:331-342 pubmed publisher
Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, et al. Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy. Br J Pharmacol. 2018;175:1486-1503 pubmed publisher
Zhang W, Yang X, Chen Y, Hu W, Liu L, Zhang X, et al. Activation of hepatic Nogo-B receptor expression-A new anti-liver steatosis mechanism of statins. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:177-190 pubmed publisher
Jing H, Zhou Y, Fang L, Ding Z, Wang D, Ke W, et al. DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-?B Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection. Front Immunol. 2017;8:1365 pubmed publisher
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, et al. PADI2-Mediated Citrullination Promotes Prostate Cancer Progression. Cancer Res. 2017;77:5755-5768 pubmed publisher
Huang W, Xu F, Zeng Q, Liu X, Gao X, Liu L. ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells. Biomed Environ Sci. 2017;30:473-481 pubmed publisher
Liu G, Zhou L, Zhang H, Chen R, Zhang Y, Li L, et al. Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20. Nat Commun. 2017;8:14824 pubmed publisher
Shen Y, Liu S, Fan J, Jin Y, Tian B, Zheng X, et al. Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions. EMBO Rep. 2017;18:536-548 pubmed publisher
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, et al. CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells. Cell Death Dis. 2017;8:e2546 pubmed publisher
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, et al. TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-?B pathway. Mol Immunol. 2017;82:123-136 pubmed publisher
Fan W, Liu T, Li X, Zhou Y, Wu M, Cui X, et al. TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway. Mol Immunol. 2017;82:114-122 pubmed publisher
Zhong S, Zhao L, Wang Y, Zhang C, Liu J, Wang P, et al. Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway. Antioxid Redox Signal. 2017;27:201-214 pubmed publisher
Zhang H, Wei D, Wan L, Yan S, Sun Y. Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/?-catenin signaling. Biochem Biophys Res Commun. 2017;482:1219-1225 pubmed publisher
Zhu F, Wang F, Yang X, Zhang J, Wu H, Zhang Z, et al. Biallelic SUN5 Mutations Cause Autosomal-Recessive Acephalic Spermatozoa Syndrome. Am J Hum Genet. 2016;99:942-949 pubmed publisher
Han T, Wan Y, Wang J, Zhao P, Yuan Y, Wang L, et al. Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway. J Immunol. 2015;194:2757-68 pubmed publisher
Duan X, Zohaib A, Li Y, Zhu B, Ye J, Wan S, et al. miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes. Cell Signal. 2015;27:61-8 pubmed publisher
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, et al. Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation. Cell Mol Life Sci. 2015;72:821-32 pubmed publisher
product information
CatalogNo :
10298-1-AP
AntigenName :
Lamin A/C
Package :
150UL
Price :
99 USD
FullName :
lamin A/C
Immunogen :
Recombinant Protein
Species :
duck, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, lamin A, lamin A/C, LDP1, LFP, LGMD1B, LMN1, LMNA, LMNC, Prelamin A/C, PRO1, progerin
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC003162
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Membrane Proteins;Organelle Marker;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:200 ; IP 1:1000 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.