This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SOD1
catalog :
10269-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 65
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 1a, 5a
  • western blot; human; 1:1000; loading ...; fig 4i
Liao Y, Zhao J, Bulek K, Tang F, Chen X, Cai G, et al. Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. Nat Commun. 2020;11:900 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 1a
  • western blot; human; 1:500; loading ...; fig 1a
Zhou Q, Zhu L, Qiu W, Liu Y, Yang F, Chen W, et al. Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice. Int J Biol Sci. 2020;16:284-297 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2a
Yoon S, Kim J. Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity. Anat Cell Biol. 2016;49:165-176 pubmed
Lu F, Lu B, Zhang L, Wen J, Wang M, Zhang S, et al. Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration. J Cell Mol Med. 2020;: pubmed publisher
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, et al. Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia. IUBMB Life. 2020;72:1659-1679 pubmed publisher
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al. Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed publisher
Zhang N, Zhang Y, Wu B, You S, Sun Y. Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury. Redox Biol. 2020;30:101419 pubmed publisher
Wang L, Yu X, Li X, Zhao Y, Wang C, Wang Z, et al. Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease. Front Aging Neurosci. 2019;11:316 pubmed publisher
Li L, Liu T, Liu L, Li S, Zhang Z, Zhang R, et al. Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury. J Bioenerg Biomembr. 2019;51:393-402 pubmed publisher
Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, et al. FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival. Cell Death Dis. 2019;10:872 pubmed publisher
Xu B, Lang L, Lian S, Guo J, Wang J, Yang H, et al. Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure. Brain Sci. 2019;9: pubmed publisher
Li J, Bao G, ALyafeai E, Ding J, Li S, Sheng S, et al. Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy. Front Pharmacol. 2019;10:1017 pubmed publisher
Shaoyong W, Li Q, Ren Z, Xiao J, Diao Z, Yang G, et al. Effects of kojic acid on boar sperm quality and anti-bacterial activity during liquid preservation at 17 C. Theriogenology. 2019;140:124-135 pubmed publisher
Li J, Guo Y, Cheng Y, Pi F, Yao W, Xie Y, et al. Determination of the Molecular Mechanism of Torularhodin against Hepatic Oxidative Damage by Transcriptome Analysis. Oxid Med Cell Longev. 2019;2019:7417263 pubmed publisher
Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, et al. DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway. Oxid Med Cell Longev. 2019;2019:5414670 pubmed publisher
Wu Q, Lu K, Zhao Z, Wang B, Liu H, Zhang S, et al. Blockade of Transient Receptor Potential Vanilloid 4 Enhances Antioxidation after Myocardial Ischemia/Reperfusion. Oxid Med Cell Longev. 2019;2019:7283683 pubmed publisher
Han J, Guo D, Sun X, Wang J, Ouyang J, Gui B. Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells. Sci Rep. 2019;9:9871 pubmed publisher
Liang M, Li H, Wang Z, Cai L, Yang L. Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats. J Sci Food Agric. 2019;: pubmed publisher
Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher
Lin J, Jia C, Wang Y, Jiang S, Jia Z, Chen N, et al. Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress. Drug Des Devel Ther. 2019;13:1461-1472 pubmed publisher
Xiong H, Chen S, Lai L, Yang H, Xu Y, Pang J, et al. Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. Neurobiol Aging. 2019;79:30-42 pubmed publisher
Wang Z, Liang M, Li H, Cai L, He H, Wu Q, et al. l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats. J Sci Food Agric. 2019;99:4849-4862 pubmed publisher
Deng X, Wang M, Hu S, Feng Y, Shao Y, Xie Y, et al. The Neuroprotective Effect of Astaxanthin on Pilocarpine-Induced Status Epilepticus in Rats. Front Cell Neurosci. 2019;13:123 pubmed publisher
Qi Y, Li R, Xu L, Yin L, Xu Y, Han X, et al. Neuroprotective Effect of Dioscin on the Aging Brain. Molecules. 2019;24: pubmed publisher
Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, et al. Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells. Front Physiol. 2019;10:223 pubmed publisher
Wu H, Wang Y, Li W, Chen H, Du L, Liu D, et al. Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome. Autophagy. 2019;:1-17 pubmed publisher
Yan X, Zhao F, Zhang S, Lei F, Wang W, Zheng Y. Hydrogen sulfide ameliorates disorders in the parafacial respiratory group region of neonatal rats caused by prenatal cigarette smoke exposure via an antioxidative effect. Environ Toxicol Pharmacol. 2019;68:80-90 pubmed publisher
Aiken C, Tarry Adkins J, Spiroski A, Nuzzo A, Ashmore T, Rolfo A, et al. Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats. J Physiol. 2019;597:2391-2401 pubmed publisher
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, et al. Protective effects of resveratrol on random-pattern skin flap survival: an experimental study. Am J Transl Res. 2019;11:379-392 pubmed
Maio N, Kim K, Holmes Hampton G, Singh A, Rouault T. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019;: pubmed publisher
Despres H, Sabra A, Anderson P, Hemraz U, Boluk Y, Sunasee R, et al. Mechanisms of the immune response cause by cationic and anionic surface functionalized cellulose nanocrystals using cell-based assays. Toxicol In Vitro. 2019;55:124-133 pubmed publisher
Tang D, Wu J, Jiao H, Wang X, Zhao J, Lin H. The development of antioxidant system in the intestinal tract of broiler chickens. Poult Sci. 2019;98:664-678 pubmed publisher
Hu Y, Zhang M, Chen Y, Yang Y, Zhang J. Postoperative intermittent fasting prevents hippocampal oxidative stress and memory deficits in a rat model of chronic cerebral hypoperfusion. Eur J Nutr. 2019;58:423-432 pubmed publisher
Kim J, Billington E, Reyes A, Notarianni T, Sage J, Agbas E, et al. Impaired Cu-Zn Superoxide Dismutase (SOD1) and Calcineurin (Cn) Interaction in ALS: A Presumed Consequence for TDP-43 and Zinc Aggregation in Tg SOD1G93A Rodent Spinal Cord Tissue. Neurochem Res. 2019;44:228-233 pubmed publisher
Meng Q, Xu J, Liang C, Liu J, Hua J, Zhang Y, et al. GPx1 is involved in the induction of protective autophagy in pancreatic cancer cells in response to glucose deprivation. Cell Death Dis. 2018;9:1187 pubmed publisher
Yang H, Lu Y, Zeng X, Li L, Zhang R, Ren Z, et al. Antichronic Gastric Ulcer Effect of Zinc-Baicalin Complex on the Acetic Acid-Induced Chronic Gastric Ulcer Rat Model. Gastroenterol Res Pract. 2018;2018:1275486 pubmed publisher
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, et al. Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy. Front Pharmacol. 2018;9:1178 pubmed publisher
Zhao F, Lei F, Yan X, Zhang S, Wang W, Zheng Y. Protective Effects of Hydrogen Sulfide Against Cigarette Smoke Exposure-Induced Placental Oxidative Damage by Alleviating Redox Imbalance via Nrf2 Pathway in Rats. Cell Physiol Biochem. 2018;48:1815-1828 pubmed publisher
Ackerman Z, Skarzinski G, Link G, Glazer M, Pappo O, Grozovski M. The Effects of Chronic Iron Overload in Rats with Acute Acetaminophen Overdose. Toxicol Pathol. 2018;46:597-607 pubmed publisher
Zhang L, Chen Z, Gong W, Zou Y, Xu F, Chen L, et al. Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1. Front Pharmacol. 2018;9:512 pubmed publisher
Xie X, Chen Q, Tao J. Astaxanthin Promotes Nrf2/ARE Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs. Mar Drugs. 2018;16: pubmed publisher
Liang M, Wang Z, Li H, Cai L, Pan J, He H, et al. l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway. Food Chem Toxicol. 2018;115:315-328 pubmed publisher
Zhu M, Tian Y, Zhang H, Ma X, Shang B, Zhang J, et al. Methylphenidate ameliorates hypoxia-induced mitochondrial damage in human neuroblastoma SH-SY5Y cells through inhibition of oxidative stress. Life Sci. 2018;197:40-45 pubmed publisher
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, et al. Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. Biochem Pharmacol. 2018;150:54-63 pubmed publisher
Gong W, Chen Z, Zou Y, Zhang L, Huang J, Liu P, et al. CKIP-1 affects the polyubiquitination of Nrf2 and Keap1 via mediating Smurf1 to resist HG-induced renal fibrosis in GMCs and diabetic mice kidneys. Free Radic Biol Med. 2018;115:338-350 pubmed publisher
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z. Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-?B pathway in vivo and in vitro. Redox Biol. 2018;15:62-73 pubmed publisher
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, et al. MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation. Antioxid Redox Signal. 2018;28:1120-1136 pubmed publisher
Xu W, Li F, Liu Z, Xu Z, Sun B, Cao J, et al. MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury. Oncotarget. 2017;8:70669-70684 pubmed publisher
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, et al. Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy. Cell Death Dis. 2017;8:e2992 pubmed publisher
Leng Z, Lin S, Wu Z, Guo Y, Cai L, Shang H, et al. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death. Autophagy. 2017;13:1404-1419 pubmed publisher
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, et al. Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate. J Cell Mol Med. 2017;21:3190-3203 pubmed publisher
Zhang T, Wang T, Cai P. Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells. Mol Med Rep. 2017;15:3566-3574 pubmed publisher
Yang G, Weng X, Zhao Y, Zhang X, Hu Y, Dai X, et al. The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nat Commun. 2017;8:14941 pubmed publisher
Gong W, Li J, Chen Z, Huang J, Chen Q, Cai W, et al. Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating CKIP-1 to resist HG-induced up-regulation of FN and ICAM-1 in GMCs and diabetic mice kidneys. Free Radic Biol Med. 2017;106:393-405 pubmed publisher
Chen Z, Xie X, Huang J, Gong W, Zhu X, Chen Q, et al. Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-?1 via Nrf2/ARE pathway in glomerular mesangial cells. Free Radic Biol Med. 2017;102:77-86 pubmed publisher
Hayashi K, Mochizuki Y, Takeuchi R, Shimizu T, Nagao M, Watabe K, et al. Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V). Acta Neuropathol Commun. 2016;4:107 pubmed
Tarry Adkins J, Fernandez Twinn D, Chen J, Hargreaves I, Neergheen V, Aiken C, et al. Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats. Dis Model Mech. 2016;9:1221-1229 pubmed
Nie H, Xue X, Liu G, Guan G, Liu H, Sun L, et al. Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase. Free Radic Res. 2016;50:1200-1213 pubmed
Wu J, Guo W, Lin S, Wang Z, Kan J, Chen S, et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis. 2016;7:e2339 pubmed publisher
Gong W, Chen C, Xiong F, Yang Z, Wang Y, Huang J, et al. CKIP-1 ameliorates high glucose-induced expression of fibronectin and intercellular cell adhesion molecule-1 by activating the Nrf2/ARE pathway in glomerular mesangial cells. Biochem Pharmacol. 2016;116:140-52 pubmed publisher
Hayashi K, Mochizuki Y, Koide R, Kawata A, Homma T, Shimizu T, et al. A Japanese familial ALS patient with autonomic failure and a p.Cys146Arg mutation in the gene for SOD1 (SOD1). Neuropathology. 2016;36:551-555 pubmed publisher
Zhao D, Li Q, Huang Q, Li X, Yin M, Wang Z, et al. Cardioprotective effect of propofol against oxygen glucose deprivation and reperfusion injury in H9c2 cells. Oxid Med Cell Longev. 2015;2015:184938 pubmed publisher
Xue H, Zhou S, Xiao L, Guo Q, Liu S, Wu Y. Hydrogen sulfide improves the endothelial dysfunction in renovascular hypertensive rats. Physiol Res. 2015;64:663-72 pubmed
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman L. MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. Mitochondrion. 2015;20:43-51 pubmed publisher
Huang K, Chen C, Hao J, Huang J, Wang S, Liu P, et al. Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells. Mol Cell Endocrinol. 2015;399:178-89 pubmed publisher
product information
CatalogNo :
10269-1-AP
AntigenName :
SOD1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
superoxide dismutase 1, soluble
Immunogen :
Recombinant Protein
Species :
broiler chick, human, mouse, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ALS, ALS1, homodimer, IPOA, SOD, SOD1, Superoxide dismutase [Cu Zn]
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC001034
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Membrane Proteins;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:1500 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.