This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
STAT3
catalog :
10253-2-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
citations: 94
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 5b
Gao L, Sang J, Cao H. Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness. Biomed Pharmacother. 2019;118:109366 pubmed publisher
Zhao S, Liang T, Zhang C, Shi D, Jiang W, Su C, et al. IL-27 Rα+ cells promoted allorejection via enhancing STAT1/3/5 phosphorylation. J Cell Mol Med. 2020;: pubmed publisher
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, et al. The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma. Aging (Albany NY). 2020;12:14391-14405 pubmed publisher
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, et al. WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy. J Cell Mol Med. 2020;: pubmed publisher
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, et al. Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation. Int J Biol Sci. 2020;16:708-718 pubmed publisher
Zhang M, Fan H, Tan S, Tang Q, Liu X, Zuo D, et al. The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation. J Ethnopharmacol. 2020;251:112549 pubmed publisher
Tian C, Gao F, Li X, Li Z. Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model. Exp Mol Pathol. 2020;113:104373 pubmed publisher
Zhang Y, Cong X, Li Z, Xue Y. Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts. Int Immunopharmacol. 2020;78:105937 pubmed publisher
Ren D, Zhao J, Sun Y, Li D, Meng Z, Wang B, et al. Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway. J Exp Clin Cancer Res. 2019;38:485 pubmed publisher
Liu Y, Che G, Di Z, Sun W, Tian J, Ren M. Calycosin-7-O-β-D-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice. Mol Cell Biochem. 2019;: pubmed publisher
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z. FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control. Front Oncol. 2019;9:1089 pubmed publisher
Huang S, Wang L, Xue N, Li C, Guo H, Ren T, et al. Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation. Theranostics. 2019;9:6745-6763 pubmed publisher
Lou D, Wang J, Wang X. miR-124 ameliorates depressive-like behavior by targeting STAT3 to regulate microglial activation. Mol Cell Probes. 2019;48:101470 pubmed publisher
Li T, Wang F, Dang Y, Dong J, Zhang Y, Zhang C, et al. P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice. Int J Biol Sci. 2019;15:2198-2210 pubmed publisher
Wang H, Yuan M, Wang S, Zhang L, Zhang R, Zou X, et al. STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1. Int J Mol Sci. 2019;20: pubmed publisher
Xing J, Li J, Fu L, Gai J, Guan J, Li Q. SIRT4 enhances the sensitivity of ER-positive breast cancer to tamoxifen by inhibiting the IL-6/STAT3 signal pathway. Cancer Med. 2019;8:7086-7097 pubmed publisher
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed publisher
Xu Y, Wang X, Guo B, Wang D, KALVAKOLANU D, Chen X, et al. Nonviral delivery of GRIM-19 gene inhibits tumor growth with reduced local and systemic complications. Hum Gene Ther. 2019;: pubmed publisher
Zhu D, Yan Q, Li Y, Liu J, Liu H, Jiang Z. Effect of Konjac Mannan Oligosaccharides on Glucose Homeostasis via the Improvement of Insulin and Leptin Resistance In Vitro and In Vivo. Nutrients. 2019;11: pubmed publisher
Xiong Y, Chang L, Tran B, Dai T, Zhong R, Mao Y, et al. ZYZ-803, a novel hydrogen sulfide-nitric oxide conjugated donor, promotes angiogenesis via cross-talk between STAT3 and CaMKII. Acta Pharmacol Sin. 2019;: pubmed publisher
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, et al. Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway. Cell Prolif. 2019;52:e12650 pubmed publisher
Liang W, Guo B, Ye J, Liu H, Deng W, Lin C, et al. Vasorin stimulates malignant progression and angiogenesis in glioma. Cancer Sci. 2019;110:2558-2572 pubmed publisher
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, et al. CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway. Front Oncol. 2019;9:461 pubmed publisher
Wang G, Xu B, Shi F, Du M, Li Y, Yu T, et al. Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response. Oxid Med Cell Longev. 2019;2019:7850324 pubmed publisher
Zhang L, Fu Y, Wang H, Guan Y, Zhu W, Guo M, et al. Severe Fever With Thrombocytopenia Syndrome Virus-Induced Macrophage Differentiation Is Regulated by miR-146. Front Immunol. 2019;10:1095 pubmed publisher
Wang S, Zhang S, He Y, Huang X, Hui Y, Tang Y. HOXA11-AS regulates JAK-STAT pathway by miR-15a-3p/STAT3 axis to promote the growth and metastasis in liver cancer. J Cell Biochem. 2019;: pubmed publisher
Bei M, Tian F, Liu N, Zheng Z, Cao X, Zhang H, et al. A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella. Med Sci Monit. 2019;25:2702-2717 pubmed publisher
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, et al. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids Surf B Biointerfaces. 2019;179:66-76 pubmed publisher
Wang J, Zhang C, Li C, Zhao D, Li S, Ma L, et al. MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway. J Cell Mol Med. 2019;23:3696-3710 pubmed publisher
Tao X, Zuo Q, Ruan H, Wang H, Jin H, Cheng Z, et al. Argininosuccinate synthase 1 suppresses cancer cell invasion by inhibiting STAT3 pathway in hepatocellular carcinoma. Acta Biochim Biophys Sin (Shanghai). 2019;51:263-276 pubmed publisher
Ma W, Xiang Y, Yang R, Zhang T, Xu J, Wu Y, et al. Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemia. J Pharmacol Sci. 2019;139:304-310 pubmed publisher
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, et al. Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer. Cancer Res. 2019;79:2604-2618 pubmed publisher
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P. Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats. Gene. 2019;697:11-18 pubmed publisher
Huang C, Lei K, Tsang N. Apoptosis and cell cycle arrest of hepatocellular carcinoma spheroids treated by an alternating electric field. Biotechnol Prog. 2019;35:e2787 pubmed publisher
Ma R, Liu Q, Zheng S, Liu T, Tan D, Lu X. PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT. J Cell Biochem. 2019;: pubmed publisher
Li Z, Yu Y, Wang M, Xu H, Han B, Jiang P, et al. Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis. Sci Rep. 2019;9:146 pubmed publisher
Yi J, Chen Z, Xu F, Wang Z, Zhang A, Liu T, et al. IL-27 Promotes Human Placenta-Derived Mesenchymal Stromal Cell Ability To Induce the Generation of CD4+IL-10+IFN-γ+ T Cells via the JAK/STAT Pathway in the Treatment of Experimental Graft-versus-Host Disease. J Immunol. 2019;202:1124-1136 pubmed publisher
Wang X, Guo S, Zhao R, Liu Y, Yang G. STAT3-Activated Long Non-Coding RNA Lung Cancer Associated Transcript 1 Drives Cell Proliferation, Migration, and Invasion in Hepatoblastoma Through Regulation of the miR-301b/STAT3 Axis. Hum Gene Ther. 2019;30:702-713 pubmed publisher
Zhao L, Du L, Zhang Y, Chao J, Duan M, Yao H, et al. Role of PUMA in the methamphetamine-induced migration of microglia. Metab Brain Dis. 2019;34:61-69 pubmed publisher
Li H, Wang J, Liu X, Cheng Q. MicroRNA-204-5p suppresses IL6-mediated inflammatory response and chemokine generation in HK-2 renal tubular epithelial cells by targeting IL6R. Biochem Cell Biol. 2019;97:109-117 pubmed publisher
Avalle L, Camporeale A, Morciano G, Caroccia N, Ghetti E, Orecchia V, et al. STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses. Cell Death Differ. 2019;26:932-942 pubmed publisher
Zheng T, Ma G, Tang M, Li Z, Xu R. IL-8 Secreted from M2 Macrophages Promoted Prostate Tumorigenesis via STAT3/MALAT1 Pathway. Int J Mol Sci. 2018;20: pubmed publisher
Gao J, Xiong R, Xiong D, Zhao W, Zhang S, Yin T, et al. The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN). Med Sci Monit. 2018;24:8533-8543 pubmed publisher
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, et al. Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro. Mol Med Rep. 2018;18:5044-5052 pubmed publisher
Jia C, Kong D, Guo Y, Li L, Quan L. Enhanced antitumor effect of combination of annexin A1 knockdown and bortezomib treatment in multiple myeloma in vitro and in vivo. Biochem Biophys Res Commun. 2018;505:720-725 pubmed publisher
Hou C, Zhou D, Wu Y, Dai X, Wang Q, Wu Y, et al. In Vitro and In Vivo Inhibitory Effect of Gujin Xiaoliu Tang in Non-Small Cell Lung Cancer. Evid Based Complement Alternat Med. 2018;2018:8936108 pubmed publisher
Li Q, Shen F, Zhao L. The relationship between lncRNA PCGEM1 and STAT3 during the occurrence and development of endometrial carcinoma. Biomed Pharmacother. 2018;107:918-928 pubmed publisher
Okumura H, Nakanishi A, Hashita T, Iwao T, Matsunaga T. Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation. Drug Metab Dispos. 2018;46:1519-1527 pubmed publisher
Wu X, Tian F, Su M, Wu M, Huang Y, Hu L, et al. BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway. Int Immunopharmacol. 2018;64:24-32 pubmed publisher
Fang X, Liu Y, Lu J, Hong H, Yuan J, Zhang Y, et al. Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2018;391:1373-1385 pubmed publisher
Yang Y, Cao Y, Chen L, Liu F, Qi Z, Cheng X, et al. Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells. Cancer Med. 2018;7:4610-4618 pubmed publisher
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, et al. Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol. 2018;234:777-788 pubmed publisher
Liu S, Gao X, Zhang L, Qin S, Wei M, Liu N, et al. A novel Anti-Cancer Stem Cells compound optimized from the natural symplostatin 4 scaffold inhibits Wnt/?-catenin signaling pathway. Eur J Med Chem. 2018;156:21-42 pubmed publisher
Wang W, Hu Y, Yang C, Zhu S, Wang X, Zhang Z, et al. Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition. Mol Cell Proteomics. 2018;17:2005-2017 pubmed publisher
Song J, Chen Z, Geng T, Wang M, Yi S, Liu K, et al. Deleting MyD88 signaling in myeloid cells promotes development of adenocarcinomas of the colon. Cancer Lett. 2018;433:65-75 pubmed publisher
Long Y, Li S, Qin J, Xie L, Gan L, Jie F, et al. Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats. Biomed Pharmacother. 2018;105:781-788 pubmed publisher
Du Y, Zhang W, Liu S, Feng X, Gao F, Liu Q. S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice. Biochem Biophys Res Commun. 2018;503:177-180 pubmed publisher
Pan H, Fu C, Huang L, Jiang Y, Deng X, Guo J, et al. Anti-Obesity Effect of Chitosan Oligosaccharide Capsules (COSCs) in Obese Rats by Ameliorating Leptin Resistance and Adipogenesis. Mar Drugs. 2018;16: pubmed publisher
Tang H, Bai Y, Shen W, Wei Y, Xu M, Zhou X, et al. Clinical significance of combined detection of interleukin-6 and tumour markers in lung cancer. Autoimmunity. 2018;51:191-198 pubmed publisher
Ma Y, Zhang H, Xiong C, Liu Z, Xu Q, Feng J, et al. CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-? signaling-induced epithelial-mesenchymal transition. Cancer Lett. 2018;: pubmed publisher
Xin D, Chu X, Bai X, Ma W, Yuan H, Qiu J, et al. l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation. Brain Behav Immun. 2018;73:222-234 pubmed publisher
Gu Y, Wu J, Yang W, Xia C, Shi X, Li H, et al. STAT3 is required for proliferation and exhibits a cell type-specific binding preference in mouse female germline stem cells. Mol Omics. 2018;14:95-102 pubmed publisher
Wang A, Li Y, Zhao Q, Fan L. Formononetin inhibits colon carcinoma cell growth and invasion by microRNA?149?mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways. Mol Med Rep. 2018;17:7721-7729 pubmed publisher
Ke M, He Q, Hong D, Li O, Zhu M, Ou W, et al. Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/?Akt?dependent Tbx?3 activation pathway. Int J Mol Med. 2018;42:131-140 pubmed publisher
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, et al. Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells. Med Sci Monit. 2018;24:1567-1573 pubmed
Guan X, Chen S, Liu Y, Wang L, Zhao Y, Zong Z. PUM1 promotes ovarian cancer proliferation, migration and invasion. Biochem Biophys Res Commun. 2018;497:313-318 pubmed publisher
Chen X, Tong C, Li H, Peng W, Li R, Luo X, et al. Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia. Hypertension. 2018;71:481-490 pubmed publisher
Shen H, Zhan M, Zhang Y, Huang S, Xu S, Huang X, et al. PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2. Cell Death Dis. 2018;9:71 pubmed publisher
Xu J, Zhou L, Wang S, Zhu J, Liu T, Jia Y, et al. Di-(2-ethylhexyl)-phthalate induces glucose metabolic disorder in adolescent rats. Environ Sci Pollut Res Int. 2018;25:3596-3607 pubmed publisher
Igbe I, Shen X, Jiao W, Qiang Z, Deng T, Li S, et al. Dietary quercetin potentiates the antiproliferative effect of interferon-? in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase. Oncotarget. 2017;8:113734-113748 pubmed publisher
Yu X, Zhang F, Mao J, Lu Y, Li J, Ma W, et al. Protein tyrosine phosphatase receptor-type ? acts as a negative regulator suppressing breast cancer. Oncotarget. 2017;8:98798-98811 pubmed publisher
Wang H, Zhu H, Guo Q, Qian T, Zhang P, Li S, et al. Overlapping Mechanisms of Peripheral Nerve Regeneration and Angiogenesis Following Sciatic Nerve Transection. Front Cell Neurosci. 2017;11:323 pubmed publisher
Wonganan O, He Y, Shen X, Wongkrajang K, Suksamrarn A, Zhang G, et al. 6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon ?/? by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells. Toxicol Appl Pharmacol. 2017;336:31-39 pubmed publisher
Yin Y, Yao S, Hu Y, Feng Y, Li M, Bian Z, et al. The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6. Clin Cancer Res. 2017;23:7375-7387 pubmed publisher
Chao J, Zhang Y, Du L, Zhou R, Wu X, Shen K, et al. Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization. Sci Rep. 2017;7:11540 pubmed publisher
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, et al. Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells. Cell Biol Int. 2017;41:1367-1378 pubmed publisher
Wang H, Huo X, Yang X, He J, Cheng L, Wang N, et al. STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4. Mol Cancer. 2017;16:136 pubmed publisher
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, et al. Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis. Mediators Inflamm. 2017;2017:3038514 pubmed publisher
Wu Y, Xu J, Xu J, Cheng J, Jiao D, Zhou C, et al. Lower Serum Levels of miR-29c-3p and miR-19b-3p as Biomarkers for Alzheimer's Disease. Tohoku J Exp Med. 2017;242:129-136 pubmed publisher
Xiao J, Gong Y, Chen Y, Yu D, Wang X, Zhang X, et al. IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway. Am J Physiol Renal Physiol. 2017;313:F310-F318 pubmed publisher
Zhang F, Lü Y, Chen Q, Zou H, Zhang J, Hu Y, et al. Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis. Cell Signal. 2017;36:67-78 pubmed publisher
Xiong Q, Wu S, Wang J, Zeng X, Chen J, Wei M, et al. Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression. Cell Biosci. 2017;7:16 pubmed publisher
Dai M, Zhu X, Liu F, Xu Q, Ge Q, Jiang S, et al. Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma. Sci Rep. 2017;7:41404 pubmed publisher
Quan Z, He Y, Luo C, Xia Y, Zhao Y, Liu N, et al. Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b. Cell Signal. 2017;32:48-58 pubmed publisher
Feng T, Cao W, Shen W, Zhang L, Gu X, Guo Y, et al. Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy. Oncotarget. 2017;8:329-344 pubmed publisher
Guan R, Zhao X, Wang X, Song N, Guo Y, Yan X, et al. Emodin alleviates bleomycin-induced pulmonary fibrosis in rats. Toxicol Lett. 2016;262:161-172 pubmed publisher
Xu B, Fu Z, Meng Y, Wu X, Wu B, Xu L, et al. Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling. Oncotarget. 2016;7:62177-62193 pubmed publisher
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, et al. Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity. Oncotarget. 2016;7:61093-61106 pubmed publisher
Huang C, Lei K, Tsang N. Paper-based microreactor array for rapid screening of cell signaling cascades. Lab Chip. 2016;16:2911-20 pubmed publisher
Hu K, Tian Y, Du Y, Huang L, Chen J, Li N, et al. Atrazine promotes RM1 prostate cancer cell proliferation by activating STAT3 signaling. Int J Oncol. 2016;48:2166-74 pubmed publisher
Yan H, Guo B, Zhang S. Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling. Biochem Biophys Res Commun. 2016;470:947-54 pubmed publisher
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, et al. IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation. BMC Pulm Med. 2015;15:13 pubmed publisher
Xing W, Liao X, Wang N, Zhao D, Zheng L, Zheng D, et al. MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1. IUBMB Life. 2015;67:202-17 pubmed publisher
Xiang M, Su H, Hong Z, Yang T, Shu G. Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling. Food Chem Toxicol. 2015;80:62-71 pubmed publisher
product information
CatalogNo :
10253-2-AP
AntigenName :
STAT3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
signal transducer and activator of transcription 3 (acute-phase response factor)
Immunogen :
Recombinant Protein
Species :
human, marmoset, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, CoIP, ChIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Acute phase response factor, APRF, HIES, STAT3
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000627
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Immunology;Membrane Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);Signal transduction;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:200 ; IP 1:2000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.