This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
RUVBL1
catalog :
10210-2-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Hintermair C, Voß K, Forné I, Heidemann M, Flatley A, Kremmer E, et al. Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression. Sci Rep. 2016;6:27401 pubmed publisher
Shin S, Lee J, Zhang J, Choi S, Bosković Z, Zhao R, et al. Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells. Sci Adv. 2020;6:eaay9131 pubmed publisher
Li H, Tong X, Xu Y, Wang M, Dai H, Shi T, et al. Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer. Carcinogenesis. 2019;: pubmed publisher
Trotman J, Agana B, Giltmier A, Wysocki V, Schoenberg D. RNA-binding proteins and heat-shock protein 90 are constituents of the cytoplasmic capping enzyme interactome. J Biol Chem. 2018;293:16596-16607 pubmed publisher
Dafinger C, Rinschen M, Borgal L, Ehrenberg C, Basten S, Franke M, et al. Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus. Exp Mol Med. 2018;50:75 pubmed publisher
Zhang X, Guo H, Han B, Zhang X, Huang Y, Yang Y, et al. Revealing A-Raf functions through its interactome. Biochim Biophys Acta Proteins Proteom. 2018;1866:849-856 pubmed publisher
Guo H, Zhang X, Peng J, Huang Y, Yang Y, Liu Y, et al. RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis. Biochem Biophys Res Commun. 2018;498:932-939 pubmed publisher
Tichon A, Perry R, Stojic L, Ulitsky I. SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA. Genes Dev. 2018;32:70-78 pubmed publisher
Huang Y, Guo X, Han B, Zhang X, An S, Zhang X, et al. Decoding the full picture of Raf1 function based on its interacting proteins. Oncotarget. 2017;8:68329-68337 pubmed publisher
Raymond A, Javary J, Breig O, Neaud V, Rosenbaum J. Reptin regulates insulin-stimulated Akt phosphorylation in hepatocellular carcinoma via the regulation of SHP-1/PTPN6. Cell Biochem Funct. 2017;35:289-295 pubmed publisher
Malinová A, Cvačková Z, Matějů D, Hořejší Z, Abéza C, Vandermoere F, et al. Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones. J Cell Biol. 2017;216:1579-1596 pubmed publisher
Fan W, Xie J, Xia J, Zhang Y, Yang M, Wang H, et al. RUVBL1-ITFG1 interaction is required for collective invasion in breast cancer. Biochim Biophys Acta Gen Subj. 2017;1861:1788-1800 pubmed publisher
Chen P, Chen H, Acharya D, Rando O, Fazzio T. R loops regulate promoter-proximal chromatin architecture and cellular differentiation. Nat Struct Mol Biol. 2015;22:999-1007 pubmed publisher
Kracker S, Di Virgilio M, Schwartzentruber J, Cuenin C, Forveille M, Deau M, et al. An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex. J Allergy Clin Immunol. 2015;135:998-1007.e6 pubmed publisher
product information
CatalogNo :
10210-2-AP
AntigenName :
RUVBL1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
RuvB-like 1 (E. coli)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, CHIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
49 kDa TBP interacting protein, ECP 54, ECP54, INO80 complex subunit H, INO80H, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, RuvB like 1, RuvB like 1 (E. coli), RUVBL1, RVB1, TAP54 alpha, TIH1, TIP49, TIP49A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC002993
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Senescence;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.