This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PCNA
catalog :
10205-2-AP
quantity :
150UL
price :
99 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 207
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2d
Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed publisher
  • western blot; human; loading ...; fig 3a
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, et al. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells. Oncol Lett. 2019;18:3081-3091 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1f
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher
  • western blot; human; loading ...; fig 5b
Guan X, Zhang M, Fu M, Luo S, Hu Q. Herpes Simplex Virus Type 2 Immediate Early Protein ICP27 Inhibits IFN-β Production in Mucosal Epithelial Cells by Antagonizing IRF3 Activation. Front Immunol. 2019;10:290 pubmed publisher
  • western blot; human; fig 3c
Li M, Cheng W, Luo J, Hu X, Nie T, Lai H, et al. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Placenta. 2017;55:81-89 pubmed publisher
Zheng S, Wan L, Ge D, Jiang F, Qian Z, Tang J, et al. LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma. Cell Death Dis. 2020;11:576 pubmed publisher
Gray S, Santiago E, Chappie J, Cohen P. Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner. Cell Rep. 2020;32:107858 pubmed publisher
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, et al. PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. Cell Death Dis. 2020;11:506 pubmed publisher
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, et al. WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy. J Cell Mol Med. 2020;: pubmed publisher
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, et al. Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway. Oncol Rep. 2020;44:103-114 pubmed publisher
Chen J, Yang H, Zhou H, Peng R, Niu Z, Kang C. PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells. Oncol Lett. 2020;20:639-646 pubmed publisher
Sun G, Zhou H, Chen K, Zeng J, Zhang Y, Yan L, et al. HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395. J Exp Clin Cancer Res. 2020;39:116 pubmed publisher
Liu Q, Tan Y, Qu T, Zhang J, Duan X, Xu H, et al. Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro. Life Sci. 2020;254:117772 pubmed publisher
Lu C, Zhang Y, Qin Y, Xu Q, Zhou R, Cui Y, et al. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis. J Med Genet. 2020;: pubmed publisher
Li H, Pan R, Lu Q, Ren C, Sun J, Wu H, et al. MicroRNA‑145‑5p inhibits osteosarcoma cell proliferation by targeting E2F transcription factor 3. Int J Mol Med. 2020;45:1317-1326 pubmed publisher
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y. ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells. Int J Oncol. 2020;56:1162-1174 pubmed publisher
Du Y, Qian Y, Tang X, Guo Y, Chen S, Jiang M, et al. Chloroquine attenuates lithium-induced NDI and proliferation of renal collecting duct cells. Am J Physiol Renal Physiol. 2020;318:F1199-F1209 pubmed publisher
Zeng J, Chen S, Li C, Ye Z, Lin B, Liang Y, et al. Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression. J Cancer. 2020;11:2068-2079 pubmed publisher
Zeng Y, Guo Z, Hu Z, Liu M, Chen Y, Chen S, et al. FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function. Biomed Pharmacother. 2020;125:110029 pubmed publisher
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, et al. Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation. Int J Biol Sci. 2020;16:708-718 pubmed publisher
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, et al. Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis. J Exp Clin Cancer Res. 2020;39:24 pubmed publisher
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, et al. MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B. Int J Mol Med. 2020;45:886-896 pubmed publisher
Hou B, Li W, Li J, Ma J, Xia P, Liu Z, et al. Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway. Oncol Rep. 2020;43:536-548 pubmed publisher
Huang B, Li W, Wang Z, Liang Y, Huang W, Nie P. Identification of a novel splice variant isoform of interferon regulatory factor 10, IRF10, in orange spotted grouper Epinephelus coioides. Fish Shellfish Immunol. 2020;97:637-647 pubmed publisher
Ren X, Tong Y, Qiu Y, Ye C, Wu N, Xiong X, et al. MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression. J Extracell Vesicles. 2020;9:1698795 pubmed publisher
Zhou J, Zhang L, Zheng H, Ge W, Huang Y, Yan Y, et al. Identification of chemoresistance-related mRNAs based on gemcitabine-resistant pancreatic cancer cell lines. Cancer Med. 2020;9:1115-1130 pubmed publisher
Jiang G, Dong H, Dong Y, Yang X. Long non‑coding RNA Unigene56159 promotes glioblastoma multiforme cell proliferation and invasion through negatively regulating microRNA‑194‑5p. Mol Med Rep. 2020;21:768-776 pubmed publisher
Li X, Liu H, Yu W, Liu X, Liu C. Tandem mass tag (TMT) proteomic analysis of fetal lungs revealed differential expression of tight junction proteins in a rat model of congenital diaphragmatic hernia. Biomed Pharmacother. 2020;121:109621 pubmed publisher
Liang L, Wang M, Liu M, Zhao W, Wang X, Shi L, et al. Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries. Toxicol In Vitro. 2020;62:104668 pubmed publisher
Hughes L, Park R, Lee M, Terry B, Lee D, Kim H, et al. Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020;457:150-162 pubmed publisher
Guo J, Zhang T, Gu J, Cai K, Deng X, Chen K, et al. Oleic Acid Protects against Hepatic Ischemia and Reperfusion Injury in Mice by Inhibiting AKT/mTOR Pathways. Oxid Med Cell Longev. 2019;2019:4842592 pubmed publisher
Pan C, Liu Q, Wu X. HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells. Cancer Manag Res. 2019;11:10145-10156 pubmed publisher
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, et al. Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy. Cell Death Dis. 2019;10:915 pubmed publisher
Liu S, Huang J, Zhang Y, Liu Y, Zuo S, Li R. MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis. Aging (Albany NY). 2019;11:10697-10710 pubmed publisher
Zhao X, Fang Y, Wang X, Yang Z, Li D, Tian M, et al. Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway. Int J Oncol. 2019;: pubmed publisher
Dong L, Li R, Li D, Wang B, Lu Y, Li P, et al. FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response. Front Pharmacol. 2019;10:1224 pubmed publisher
Zhou H, Xiong Y, Peng L, Wang R, Zhang H, Fu Z. LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway. J Cell Biochem. 2019;: pubmed publisher
Yan S, Zhou N, Zhang D, Zhang K, Zheng W, Bao Y, et al. PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
Sun D, Yang L, Cao H, Shen Z, Song H. Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells. Cell Biol Int. 2019;: pubmed publisher
Hu S, Zhao X, Mao G, Zhang Z, Wen X, Zhang C, et al. MicroRNA-455-3p promotes TGF-β signaling and inhibits osteoarthritis development by directly targeting PAK2. Exp Mol Med. 2019;51:118 pubmed publisher
Li Y, Shen R, Wu H, Yu L, Wang Z, Wang D. Liver changes induced by cadmium poisoning distinguished by confocal Raman imaging. Spectrochim Acta A Mol Biomol Spectrosc. 2019;225:117483 pubmed publisher
Fang Y, Shen Z, Zhan Y, Feng X, Chen K, Li Y, et al. CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis. Nat Commun. 2019;10:3981 pubmed publisher
Li T, Zha L, Luo H, Li S, Zhao L, He J, et al. Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension. Aging Dis. 2019;10:731-745 pubmed publisher
Chen K, Guo Z, Luo Y, Yuan J, Mo Z. UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ. Biomed Res Int. 2019;2019:9456847 pubmed publisher
Han N, Xu H, Yu N, Wu Y, Yu L. MiR-203a-3p inhibits retinal angiogenesis and alleviates proliferative diabetic retinopathy in oxygen-induced retinopathy (OIR) rat model via targeting VEGFA and HIF-1α. Clin Exp Pharmacol Physiol. 2019;: pubmed publisher
Wu J, Li X, Li D, Ren X, Li Y, Herter E, et al. MicroRNA-34 family enhances wound inflammation by targeting LGR4. J Invest Dermatol. 2019;: pubmed publisher
Li B, He S, Liu R, Huang L, Liu G, Wang R, et al. Total glucosides of paeony attenuates animal psoriasis induced inflammatory response through inhibiting STAT1 and STAT3 phosphorylation. J Ethnopharmacol. 2019;243:112121 pubmed publisher
Zhao J, Cao J, Yu L, Ma H. Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages. Mol Immunol. 2019;114:114-122 pubmed publisher
Zhang Q, Cao W, Wang X, Zhang M, Lu X, Chen J, et al. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Phytother Res. 2019;: pubmed publisher
Zhang H, Chen F, He S, Liang Y, Wang Z, Wang L, et al. In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats. Stem Cell Res Ther. 2019;10:208 pubmed publisher
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, et al. Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer. Mol Cancer Res. 2019;: pubmed publisher
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, et al. Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel. Biochem Biophys Res Commun. 2019;516:1066-1072 pubmed publisher
Cheng Z, Xin H, Han T. BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin. Cell Adh Migr. 2019;13:249-259 pubmed publisher
Cui X, Sun J, Liang C, Zheng Q, Yang X, Liu S, et al. Progesterone promotes embryo adhesion by upregulating c-Fos/c-Jun transcription factor-mediate poFUT1 expression. Biol Reprod. 2019;: pubmed publisher
Chen X, Tan W, Li W, Li W, Zhu S, Zhong J, et al. miR-1226-3p Promotes Sorafenib Sensitivity of Hepatocellular Carcinoma via Downregulation of DUSP4 Expression. J Cancer. 2019;10:2745-2753 pubmed publisher
Wang D, Xu H, Wu B, Jiang S, Pan H, Wang R, et al. Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension. Int J Mol Med. 2019;44:871-884 pubmed publisher
Liu X, Ma W, Ma J, Xiao L, Hao D. Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF. Pathol Res Pract. 2019;215:152492 pubmed publisher
Cao X, Fang X, Malik W, He Y, Li X, Xie M, et al. TRB3 interacts with ERK and JNK and contributes to the proliferation, apoptosis, and migration of lung adenocarcinoma cells. J Cell Physiol. 2019;: pubmed publisher
Wang H, Ma Y, Lin Y, Liu J, Chen R, Xu B, et al. An Isoxazole Derivative SHU00238 Suppresses Colorectal Cancer Growth through miRNAs Regulation. Molecules. 2019;24: pubmed publisher
Wang X, Yu N, Peng H, Hu Z, Sun Y, Zhu X, et al. The profiling of bioactives in Akebia trifoliata pericarp and metabolites, bioavailability and in vivo anti-inflammatory activities in DSS-induced colitis mice. Food Funct. 2019;: pubmed publisher
Yang Y, Zhang D, Qin H, Liu S, Yan Q. poFUT1 promotes endometrial decidualization by enhancing the O-fucosylation of Notch1. EBioMedicine. 2019;: pubmed publisher
Zhao Y, Xiang R, Peng X, Dong Q, Li D, Yu G, et al. Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling. Respir Res. 2019;20:121 pubmed publisher
Zhang L, Shan X, Chen Q, Xu D, Fan X, Yu M, et al. Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial-mesenchymal transition of cutaneous squamous cell carcinoma through c-Jun acetylation. J Cell Physiol. 2019;234:22207-22219 pubmed publisher
Wang Z, Zhao J, Wang T, Du X, Xie J. Fine-particulate matter aggravates cigarette smoke extract-induced airway inflammation via Wnt5a-ERK pathway in COPD. Int J Chron Obstruct Pulmon Dis. 2019;14:979-994 pubmed publisher
Li S, Lu D, Tang J, Min J, Hu M, Li Y, et al. Electrical Stimulation Activates Fibroblasts through the Elevation of Intracellular Free Ca2+: Potential Mechanism of Pelvic Electrical Stimulation Therapy. Biomed Res Int. 2019;2019:7387803 pubmed publisher
Zheng Y, Zhu G, He J, Wang G, Li D, Zhang F. Icariin targets Nrf2 signaling to inhibit microglia-mediated neuroinflammation. Int Immunopharmacol. 2019;73:304-311 pubmed publisher
Liu Y, Xu Y, Zhu J, Li H, Zhang J, Yang G, et al. Metformin Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Activation of Adenosine Monophosphate-Activated Protein Kinase. J Vasc Res. 2019;:1-12 pubmed publisher
Sun Z, Liu Y, Yu F, Xu Y, Yanli L, Liu N. Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline. Biomed Pharmacother. 2019;115:108933 pubmed publisher
Wang C, Zheng P, Adeniran S, Ma M, Huang F, Adegoke E, et al. Thyroid hormone (T3) is involved in inhibiting the proliferation of newborn calf Sertoli cells via the PI3K/Akt signaling pathway in vitro. Theriogenology. 2019;133:1-9 pubmed publisher
Tang F, Liu M, Zeng O, Tan W, Long J, Liu S, et al. Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway. Technol Health Care. 2019;27:331-343 pubmed publisher
Zhang B, Wang G, He J, Yang Q, Li D, Li J, et al. Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner. J Neuroinflammation. 2019;16:92 pubmed publisher
Zhu M, Wei C, Lin J, Dong S, Gao D, Chen J, et al. UHRF1 is regulated by miR-124-3p and promotes cell proliferation in intrahepatic cholangiocarcinoma. J Cell Physiol. 2019;: pubmed publisher
Dong S, Ji J, Hu L, Wang H. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration. Life Sci. 2019;227:20-29 pubmed publisher
Hu C, Liu Y, Teng M, Jiao K, Zhen J, Wu M, et al. Resveratrol inhibits the proliferation of estrogen receptor-positive breast cancer cells by suppressing EZH2 through the modulation of ERK1/2 signaling. Cell Biol Toxicol. 2019;: pubmed publisher
Cao X, He Y, Li X, Xu Y, Liu X. The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs. Am J Transl Res. 2019;11:641-654 pubmed
Zhu L, Li D, Chen C, Wang G, Shi J, Zhang F. Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity. Biotechnol Appl Biochem. 2019;: pubmed publisher
Li Q, Wu J, Xu Y, Liu L, Xie J. Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling. Respir Res. 2019;20:52 pubmed publisher
Xu C, Tian G, Jiang C, Xue H, Kuerbanjiang M, Sun L, et al. NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6. Cell Death Dis. 2019;10:217 pubmed publisher
Chen J, Yu Y, Li H, Hu Q, Chen X, He Y, et al. Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer. Mol Cancer. 2019;18:33 pubmed publisher
Chen D, Zang Y, Qiu Y, Zhang F, Chen A, Wang J, et al. BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension. Oxid Med Cell Longev. 2019;2019:5018410 pubmed publisher
Wei C, Dong X, Lu H, Tong F, Chen L, Zhang R, et al. LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway. J Exp Clin Cancer Res. 2019;38:95 pubmed publisher
Ma Z, Cui X, Lu L, Chen G, Yang Y, Hu Y, et al. Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis. Stem Cell Res Ther. 2019;10:60 pubmed publisher
Jiang J, Fan Y, Zhang W, Shen Y, Liu T, Yao M, et al. Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway. Int J Biol Sci. 2019;15:253-264 pubmed publisher
Vickaryous M, Gilbert E. Reptile Embryology and Regeneration. Methods Mol Biol. 2019;1920:219-246 pubmed publisher
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, et al. Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. EBioMedicine. 2019;40:92-105 pubmed publisher
Wang M, Li H, Zhao Y, Lv C, Zhou G. Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor-β1-mediated Smad and mitogen-activated protein kinase signaling transductions in vivo and in vitro. Exp Ther Med. 2019;17:251-259 pubmed publisher
Liu J, Feng X, Tian Y, Wang K, Gao F, Yang L, et al. Knockdown of TRIM27 expression suppresses the dysfunction of mesangial cells in lupus nephritis by FoxO1 pathway. J Cell Physiol. 2019;234:11555-11566 pubmed publisher
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed publisher
Li Y, Zheng Q, Sun D, Cui X, CHEN S, Bulbul A, et al. Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome. J Cell Physiol. 2019;234:7435-7447 pubmed publisher
Hu A, Huang J, Li S, Gao Y, Wu L, Deng J, et al. Involvement of stromal cell-derived factor-1α (SDF-1α), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury. Biomed Pharmacother. 2019;110:887-894 pubmed publisher
Liu Y, Jia L, Min D, Xu Y, Zhu J, Sun Z. Baicalin inhibits proliferation and promotes apoptosis of vascular smooth muscle cells by regulating the MEG3/p53 pathway following treatment with ox‑LDL. Int J Mol Med. 2019;43:901-913 pubmed publisher
Cui D, Zhao Y, Xu J. Activation of CXCL5-CXCR2 axis promotes proliferation and accelerates G1 to S phase transition of papillary thyroid carcinoma cells and activates JNK and p38 pathways. Cancer Biol Ther. 2019;20:608-616 pubmed publisher
Jiang P, Li G, Zhou X, Wang C, Qiao Y, Liao D, et al. Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway. Chemosphere. 2019;214:430-435 pubmed publisher
Tang Y, Wang C, Wang Y, Zhang J, Wang F, Li L, et al. Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway. Am J Transl Res. 2018;10:4141-4151 pubmed
Peng S, Pang Y, Zhu Q, Kang J, Liu M, Wang Z. Chlorogenic Acid Functions as a Novel Agonist of PPARγ2 during the Differentiation of Mouse 3T3-L1 Preadipocytes. Biomed Res Int. 2018;2018:8594767 pubmed publisher
Zhang M, Deng X, Guan X, Geng L, Fu M, Zhang B, et al. Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4. Front Immunol. 2018;9:2932 pubmed publisher
You S, Wang F, Hu Q, Li P, Zhang C, Yu Y, et al. Abnormal expression of YEATS4 associates with poor prognosis and promotes cell proliferation of hepatic carcinoma cell by regulation the TCEA1/DDX3 axis. Am J Cancer Res. 2018;8:2076-2087 pubmed
Dai J, Zhou Q, Chen J, Rexius Hall M, Rehman J, Zhou G. Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. Nat Commun. 2018;9:3850 pubmed publisher
Wang Y, Chen M. Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury. Biochem Biophys Res Commun. 2018;505:151-156 pubmed publisher
Wang X, Li H, Lu X, Wen C, Huo Z, Shi M, et al. Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma. Cell Death Dis. 2018;9:940 pubmed publisher
Hsu C, Lui K, Chi L, Kuo Y, Chao Y, Yeh C, et al. Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma. J Exp Clin Cancer Res. 2018;37:233 pubmed publisher
Yu M, Wang H, Liu J, Qin H, Liu S, Yan Q. The sialyltransferase ST3Gal3 facilitates the receptivity of the uterine endometrium in vitro and in vivo. FEBS Lett. 2018;592:3696-3707 pubmed publisher
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, et al. Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. Mol Pharm. 2018;15:4974-4984 pubmed publisher
Xu X, Shi R, Zheng L, Guo Z, Wang L, Zhou M, et al. SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress. J Mol Cell Biol. 2018;10:460-474 pubmed publisher
Dai T, Wang B, Xiao Z, You Y, Tian S. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. 2018;390:151-159 pubmed publisher
Chen Y, Li Y, Wang X, Meng Y, Zhang Q, Zhu J, et al. Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway. Phytother Res. 2018;32:2447-2455 pubmed publisher
Zhou L, Ouyang R, Luo H, Peng Y, Chen P, Ren S, et al. Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome. Oxid Med Cell Longev. 2018;2018:3529709 pubmed publisher
Dai J, Zhou Q, Tang H, Chen T, Li J, Raychaudhuri P, et al. Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cell Signal. 2018;51:119-129 pubmed publisher
Zhang Y, Yi F, Wang L, Wang Z, Zhang N, Wang Z, et al. Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration. Int J Biol Sci. 2018;14:1081-1089 pubmed publisher
Yang C, Chang C, Chang M, Shyur L. Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice. Int J Cancer. 2018;143:3248-3261 pubmed publisher
Renganathan B, Durairaj V, Kirman D, Esubonteng P, Ang S, Ge R. Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism. Cancers (Basel). 2018;10: pubmed publisher
Zhang Y, Ye X, Chen L, Wu Q, Gao Y, Li Y. PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development. Int J Biol Sci. 2018;14:531-541 pubmed publisher
Qi H, Lu Y, Lv J, Wu H, Lu J, Zhang C, et al. The long noncoding RNA lncPARP1 contributes to progression of hepatocellular carcinoma through up-regulation of PARP1. Biosci Rep. 2018;38: pubmed publisher
Song X, Tan S, Wu Z, Xu L, Wang Z, Xu Y, et al. HBV suppresses ZHX2 expression to promote proliferation of HCC through miR-155 activation. Int J Cancer. 2018;143:3120-3130 pubmed publisher
Li Y, Li G, Sun L, Li L, Liu Y, Kong D, et al. Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response. Oxid Med Cell Longev. 2018;2018:7616852 pubmed publisher
Tang D, Zhang J, Yan T, Wei J, Jiang X, Zhang D, et al. FG-4592 Accelerates Cutaneous Wound Healing by Epidermal Stem Cell Activation via HIF-1α Stabilization. Cell Physiol Biochem. 2018;46:2460-2470 pubmed publisher
Zheng Q, Zhou F, Cui X, Liu M, Li Y, Liu S, et al. Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level. Cell Physiol Biochem. 2018;46:2297-2310 pubmed publisher
Chen T, Huang J, Dai J, Zhou Q, Raj J, Zhou G. PAI-1 is a novel component of the miR-17~92 signaling that regulates pulmonary artery smooth muscle cell phenotypes. Am J Physiol Lung Cell Mol Physiol. 2018;315:L149-L161 pubmed publisher
Qi F, Zuo Z, Hu S, Xia Y, Song D, Kong J, et al. An enriched environment restores hepatitis B vaccination-mediated impairments in synaptic function through IFN-γ/Arginase1 signaling. Brain Behav Immun. 2018;71:116-132 pubmed publisher
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, et al. Wnt/?-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention. Toxicol Lett. 2018;291:70-76 pubmed publisher
Li M, Ruan L, Chen C, Xing Y, Hong W, Du R, et al. Protective effects of Polygonum multiflorum on ischemic stroke rat model analysed by 1H NMR metabolic profiling. J Pharm Biomed Anal. 2018;155:91-103 pubmed publisher
Zhang J, Lu Q, Feng W, Wang H, Tang Z, Cheng H, et al. Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ. Biomed Pharmacother. 2018;102:711-717 pubmed publisher
Zhang Q, Li X, Chen Y, Chen J, Zhu J, Meng Y, et al. Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells. Cancer Chemother Pharmacol. 2018;81:969-977 pubmed publisher
Yang S, Xing L, Gu L, Cheng H, Feng Y, Zhang Y. Combination of RIZ1 Overexpression and Radiotherapy Contributes to Apoptosis and DNA Damage of HeLa and SiHa Cervical Cancer Cells. Basic Clin Pharmacol Toxicol. 2018;123:137-146 pubmed publisher
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product information
CatalogNo :
10205-2-AP
AntigenName :
PCNA
Package :
150UL
Price :
99 USD
FullName :
proliferating cell nuclear antigen
Immunogen :
Recombinant Protein
Species :
american alligator, cow, human, mouse, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Cyclin, PCNA
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000491
Category :
Binding Proteins;Cell Cycle;Cell/Tissue Markers;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:200 ; IHC 1:500 ; IP 1:1500 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.