This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
HDAC1
catalog :
10197-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4b
Zhu Y, Wang G, Cingoz O, Goff S. NP220 mediates silencing of unintegrated retroviral DNA. Nature. 2018;564:278-282 pubmed publisher
Sanna S, Esposito S, Masala A, Sini P, Nieddu G, Galioto M, et al. HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo. Cell Death Dis. 2020;11:369 pubmed publisher
Andrade F, Nguyen N, Warri A, Hilakivi Clarke L. Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy. Sci Rep. 2019;9:20271 pubmed publisher
Liu M, Zhong J, Zeng Z, Huang K, Ye Z, Deng S, et al. Hypoxia-induced feedback of HIF-1α and lncRNA-CF129 contributes to pancreatic cancer progression through stabilization of p53 protein. Theranostics. 2019;9:4795-4810 pubmed publisher
Feng K, Deng F, Hu Z, Wang H, Ning Y. Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1. J Biol Chem. 2019;294:9503-9517 pubmed publisher
Jiang Z, Yang H, Zhang X, Wang Z, Rong R, Wang X. Histone deacetylase-1 as a prognostic factor and mediator of gastric cancer progression by enhancing glycolysis. Hum Pathol. 2019;85:194-201 pubmed publisher
Zhong S, Li L, Zhang Y, Zhang L, Lu J, Guo S, et al. Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation. J Clin Invest. 2019;129:252-267 pubmed publisher
Zhang N, Zhang H, Liu Y, Su P, Zhang J, Wang X, et al. SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2. Cell Death Differ. 2019;26:843-859 pubmed publisher
He B, Dai L, Zhang X, Chen D, Wu J, Feng X, et al. The HDAC Inhibitor Quisinostat (JNJ-26481585) Supresses Hepatocellular Carcinoma alone and Synergistically in Combination with Sorafenib by G0/G1 phase arrest and Apoptosis induction. Int J Biol Sci. 2018;14:1845-1858 pubmed publisher
Bando H, Sakaguchi N, Lee Y, Pradipta A, Ma J, Tanaka S, et al. Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells. Front Immunol. 2018;9:2073 pubmed publisher
Banks C, Miah S, Adams M, Eubanks C, Thornton J, Florens L, et al. Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly. Sci Rep. 2018;8:13712 pubmed publisher
Duan H, Zhou K, Wang T, Zhang Y, Li Y, Hua Y, et al. Disruption of Planar Cell Polarity Pathway Attributable to Valproic Acid-Induced Congenital Heart Disease through Hdac3 Participation in Mice. Chin Med J (Engl). 2018;131:2080-2088 pubmed publisher
Xiao D, Wang H, Hao L, Guo X, Ma X, Qian Y, et al. The roles of SMYD4 in epigenetic regulation of cardiac development in zebrafish. PLoS Genet. 2018;14:e1007578 pubmed publisher
Wang J, Liu H, Gao L, Liu X. Impaired FGF10 Signaling and Epithelial Development in Experimental Lung Hypoplasia With Esophageal Atresia. Front Pediatr. 2018;6:109 pubmed publisher
Wu Y, Xu Y, Huang X, Ye D, Han M, Wang H. Regulatory Roles of Histone Deacetylases 1 and 2 in Pb-induced Neurotoxicity. Toxicol Sci. 2018;162:688-701 pubmed publisher
Ma Y, Yuan S, Tian X, Lin S, Wei S, Hu T, et al. ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation. J Cell Biochem. 2018;119:3030-3043 pubmed publisher
Duan H, Ma D, Zhou K, Wang T, Zhang Y, Li Y, et al. Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line. Chin Med J (Engl). 2017;130:1352-1360 pubmed publisher
Duan H, Wang C, Zhou K, Wang T, Li Y, Qiu D, et al. The effect of histone deacetylase inhibition on the expression of P-glycoprotein in human placental trophoblast cell lines. Placenta. 2017;49:37-47 pubmed publisher
Wang F, Zhao J, Liu D, Zhao T, Lu Z, Zhu L, et al. Capsaicin reactivates hMOF in gastric cancer cells and induces cell growth inhibition. Cancer Biol Ther. 2016;17:1117-1125 pubmed
He X, Zhu W, Yuan P, Jiang S, Li D, Zhang H, et al. miR-155 downregulates ErbB2 and suppresses ErbB2-induced malignant transformation of breast epithelial cells. Oncogene. 2016;35:6015-6025 pubmed publisher
Sun J, Ding C, Yang Z, Liu T, Zhang X, Zhao C, et al. The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition. J Transl Med. 2016;14:42 pubmed publisher
Shi Y, Xu L, Peng K, Wu W, Wu R, Liu Z, et al. Specific immunotherapy in combination with Clostridium butyricum inhibits allergic inflammation in the mouse intestine. Sci Rep. 2015;5:17651 pubmed publisher
Shang J, Wan Q, Wang X, Duan Y, Wang Z, Wei X, et al. Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-mediated HuR signaling in diabetic nephropathy. Free Radic Biol Med. 2015;79:217-27 pubmed publisher
Cai M, Hu Z, Liu J, Gao J, Tan M, Zhang D, et al. Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis. Oncol Rep. 2015;33:685-92 pubmed publisher
Zhao B, Zhao W, Wang Y, Xu Y, Xu J, Tang K, et al. Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways. Oncotarget. 2015;6:10116-33 pubmed
product information
CatalogNo :
10197-1-AP
AntigenName :
HDAC1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
histone deacetylase 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, co-IP, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
GON 10, HD1, HDAC1, histone deacetylase 1, RPD3, RPD3L1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000301
Category :
Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Disease Related;Metabolism;Organelle Marker;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:50 ; IP 1:500 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.