This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TGFBI / BIGH3
catalog :
10188-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry
citations: 22
Reference
Kitamoto K, Taketani Y, Fujii W, Inamochi A, Toyono T, Miyai T, et al. Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair. Sci Rep. 2020;10:2000 pubmed publisher
Wang B, Chi K, Shen R, Zheng S, Guo Y, Li J, et al. TGFBI Promotes Tumor Growth and is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma. J Cancer. 2019;10:4902-4912 pubmed publisher
Lang K, Kahveci S, Bonberg N, Wichert K, Behrens T, Hovanec J, et al. TGFBI Protein Is Increased in the Urine of Patients with High-Grade Urothelial Carcinomas, and Promotes Cell Proliferation and Migration. Int J Mol Sci. 2019;20: pubmed publisher
Zou J, Huang R, Li H, Wang B, Chen Y, Chen S, et al. Secreted TGF-beta-induced protein promotes aggressive progression in bladder cancer cells. Cancer Manag Res. 2019;11:6995-7006 pubmed publisher
Zhang X, Liu L, Dou C, Cheng P, Liu L, Liu H, et al. PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia. Mol Ther Nucleic Acids. 2019;17:678-687 pubmed publisher
Zhu H, Chen H, Wang J, Zhou L, Liu S. Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer. Onco Targets Ther. 2019;12:3441-3457 pubmed publisher
Araki Sasaki K, Osakabe Y, Fujita K, Miyata K, Hirano K. Collagen fiber changes related to keratoconus with secondary corneal amyloidosis. Int Med Case Rep J. 2018;11:193-199 pubmed publisher
Sato T, Muramatsu T, Tanabe M, Inazawa J. Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line. Cancer Sci. 2018;109:3623-3633 pubmed publisher
He H, Sinha I, Fan R, Haldosén L, Yan F, Zhao C, et al. c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer. Oncogene. 2018;37:2586-2600 pubmed publisher
Pan T, Lin S, Yu K, Yu G, Song J, Lewis V, et al. BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation. Neoplasia. 2018;20:32-43 pubmed publisher
Chen W, Tsai Y, Yeh H, Suau F, Jiang K, Shao A, et al. Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer. Sci Signal. 2017;10: pubmed publisher
Kontostathi G, Zoidakis J, Makridakis M, Lygirou V, Mermelekas G, Papadopoulos T, et al. Cervical Cancer Cell Line Secretome Highlights the Roles of Transforming Growth Factor-Beta-Induced Protein ig-h3, Peroxiredoxin-2, and NRF2 on Cervical Carcinogenesis. Biomed Res Int. 2017;2017:4180703 pubmed publisher
Qiu W, Zheng L, Pan F, Wang B, Yao Y. New histopathologic and ultrastructural findings in Reis-Bücklers corneal dystrophy caused by the Arg124Leu mutation of TGFBI gene. BMC Ophthalmol. 2016;16:158 pubmed publisher
He C, Sun D, Bai X, Li Y, Xu H, Xu S. Clinical implications of transforming growth factor-beta-induced gene-h3 protein expression in lung cancer. Onco Targets Ther. 2016;9:4983-7 pubmed publisher
Huang J, Lin W, Li S, Shih M, Chan W, Shin J, et al. Comparative proteomic analysis of extracellular secreted proteins expressed by two pathogenic Acanthamoeba castellanii clinical isolates and a non-pathogenic ATCC strain. Exp Parasitol. 2016;166:60-7 pubmed publisher
Ahlfeld S, Wang J, Gao Y, Snider P, Conway S. Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia. Am J Pathol. 2016;186:777-93 pubmed publisher
Allaman Pillet N, Oberson A, Bustamante M, Tasinato A, Hummler E, Schorderet D. Tgfbi/Bigh3 silencing activates ERK in mouse retina. Exp Eye Res. 2015;140:159-170 pubmed publisher
Lim S, Jin L, Piao S, Chung B, Yang C. Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury. Lab Invest. 2015;95:1174-85 pubmed publisher
Yamazoe K, Yoshida S, Yasuda M, Hatou S, Inagaki E, Ogawa Y, et al. Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2. PLoS ONE. 2015;10:e0133397 pubmed publisher
Mężyk Kopeć R, Wyroba B, Stalińska K, Próchnicki T, Wiatrowska K, Kilarski W, et al. ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells. PLoS ONE. 2015;10:e0132661 pubmed publisher
Han B, Cai H, Chen Y, Hu B, Luo H, Wu Y, et al. The role of TGFBI (βig-H3) in gastrointestinal tract tumorigenesis. Mol Cancer. 2015;14:64 pubmed publisher
Lebdai S, Verhoest G, Parikh H, Jacquet S, Bensalah K, Chautard D, et al. Identification and validation of TGFBI as a promising prognosis marker of clear cell renal cell carcinoma. Urol Oncol. 2015;33:69.e11-8 pubmed publisher
product information
CatalogNo :
10188-1-AP
AntigenName :
TGFBI / BIGH3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
transforming growth factor, beta-induced, 68kDa
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, Neutralization, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Beta ig h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, LCD1, RGD CAP, TGFBI
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000097
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:100 ; IP 1:300 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.