Mitofilin | Proteintech Group 10179-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

Mitofilin

catalog :

10179-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 21

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 6a	Straub I, Janer A, Weraarpachai W, Zinman L, Robertson J, Rogaeva E, et al. Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS. Hum Mol Genet. 2018;27:178-189 pubmed publisher
	Stephan T, Brüser C, Deckers M, Steyer A, Balzarotti F, Barbot M, et al. MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation. EMBO J. 2020;39:e104105 pubmed publisher
	Liu Y, Huang X, Nguyen D, Shammas M, Wu B, Dombi E, et al. Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations. Hum Mol Genet. 2020;29:1547-1567 pubmed publisher
	Ayanlaja A, Ji G, Wang J, Gao Y, Cheng B, Kanwore K, et al. Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression. Cell Commun Signal. 2020;18:24 pubmed publisher
	Wolf D, Segawa M, Kondadi A, Anand R, Bailey S, Reichert A, et al. Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent. EMBO J. 2019;38:e101056 pubmed publisher
	Violitzi F, Perivolidi V, Thireou T, Grivas I, Haralambous S, Samiotaki M, et al. Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice. J Proteome Res. 2019;18:3896-3912 pubmed publisher
	Wang P, Deng J, Dong J, Liu J, Bigio E, Mesulam M, et al. TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response. PLoS Genet. 2019;15:e1007947 pubmed publisher
	Balsa E, Soustek M, Thomas A, Cogliati S, Garcia Poyatos C, Martín García E, et al. ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis. Mol Cell. 2019;74:877-890.e6 pubmed publisher
	Dovey C, Diep J, Clarke B, Hale A, McNamara D, Guo H, et al. MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. Mol Cell. 2018;70:936-948.e7 pubmed publisher
	Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, et al. Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology. Cell Rep. 2018;23:2989-3005 pubmed publisher
	Kelly F, Wei B, Cygan A, Parker M, Boulanger M, Boothroyd J. Toxoplasma gondii MAF1b Binds the Host Cell MIB Complex To Mediate Mitochondrial Association. mSphere. 2017;2: pubmed publisher
	Terzenidou M, Segklia A, Kano T, Papastefanaki F, Karakostas A, Charalambous M, et al. Novel insights into SLC25A46-related pathologies in a genetic mouse model. PLoS Genet. 2017;13:e1006656 pubmed publisher
	Steffen J, Vashisht A, Wan J, Jen J, Claypool S, Wohlschlegel J, et al. Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. Mol Biol Cell. 2017;28:600-612 pubmed publisher
	Glytsou C, Calvo E, Cogliati S, Mehrotra A, Anastasia I, Rigoni G, et al. Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control. Cell Rep. 2016;17:3024-3034 pubmed publisher
	Zeharia A, Friedman J, Tobar A, Saada A, Konen O, Fellig Y, et al. Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit. Eur J Hum Genet. 2016;24:1778-1782 pubmed publisher
	Wang Y, Wu F, Pan H, Zheng W, Feng C, Wang Y, et al. Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology. Sci Rep. 2016;6:22244 pubmed publisher
	Mateo R, Nagamine C, Kirkegaard K. Suppression of Drug Resistance in Dengue Virus. MBio. 2015;6:e01960-15 pubmed publisher
	Genin E, Plutino M, Bannwarth S, Villa E, Cisneros Barroso E, Roy M, et al. CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis. EMBO Mol Med. 2016;8:58-72 pubmed publisher
	Ding C, Wu Z, Huang L, Wang Y, Xue J, Chen S, et al. Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. Sci Rep. 2015;5:16064 pubmed publisher
	Petrungaro C, Zimmermann K, KÃ¼ttner V, Fischer M, Dengjel J, Bogeski I, et al. The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake. Cell Metab. 2015;22:721-33 pubmed publisher
	Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, et al. Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ. 2016;23:380-92 pubmed publisher

product information

CatalogNo :

10179-1-AP

AntigenName :

Mitofilin

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

inner membrane protein, mitochondrial (mitofilin)

Immunogen :

Recombinant Protein

Species :

hamster, human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, FC, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

HMP, IMMT, MIC60, MINOS2, Mitofilin, P87, P87/89, P89, PIG4, PIG52

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC002412

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Organelle Marker;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

FC 1:0 ; IF 1:50 ; IHC 1:100 ; IP 1:1000 ; WB 1:1000 ;