SIRT3 | Proteintech Group 10099-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

SIRT3

catalog :

10099-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

citations: 21

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2d, 7c	Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed publisher
	Han D, Jiang L, Gu X, Huang S, Pang J, Wu Y, et al. SIRT3 deficiency is resistant to autophagy-dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels. J Cell Physiol. 2020;: pubmed publisher
	Feng X, Wang Y, Chen W, Xu S, Li L, Geng Y, et al. SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity. Aging (Albany NY). 2020;12:4178-4192 pubmed publisher
	Xu L, Hao L, Ma J, Liu J, Hasim A. SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase. Mol Cell Biochem. 2019;: pubmed publisher
	Fan C, Ma Q, Xu M, Qiao Y, Zhang Y, Li P, et al. Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
	Sun Y, Teng Z, Sun X, Zhang L, Chen J, Wang B, et al. Exogenous H2S reduces the acetylation levels of mitochondrial respiratory enzymes via regulating the NAD+-SIRT3 pathway in cardiac tissues of db/db mice. Am J Physiol Endocrinol Metab. 2019;317:E284-E297 pubmed publisher
	Wang Z, Chen Z, Jiang Z, Luo P, Liu L, Huang Y, et al. Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents. Nat Commun. 2019;10:2538 pubmed publisher
	Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, et al. MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1. Pharmacol Res. 2019;146:104276 pubmed publisher
	Chen L, He P, Yang J, Yang Y, Wang K, Amend B, et al. NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. Mol Med Rep. 2019;19:2960-2968 pubmed publisher
	Xu W, Hu Q, Qin Y, Zhang B, Liu W, Ni Q, et al. Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer. World J Gastroenterol. 2018;24:4893-4905 pubmed publisher
	Song Y, Li S, Geng W, Luo R, Liu W, Tu J, et al. Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration. Redox Biol. 2018;19:339-353 pubmed publisher
	Jang Y, Kwon I, Song W, Cosio Lima L, Taylor S, Lee Y. Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD. Life Sci. 2018;209:455-465 pubmed publisher
	Yang Y, Cao Y, Chen L, Liu F, Qi Z, Cheng X, et al. Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells. Cancer Med. 2018;7:4610-4618 pubmed publisher
	Sun Y, Tian Z, Liu N, Zhang L, Gao Z, Sun X, et al. Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice. J Mol Med (Berl). 2018;96:281-299 pubmed publisher
	Xing S, Li J, Chen L, Yang Y, He P, Li J, et al. Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3. Mech Ageing Dev. 2018;175:1-6 pubmed publisher
	Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, et al. Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation. Toxicol Lett. 2018;284:37-45 pubmed publisher
	Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, et al. Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling. Nat Commun. 2017;8:413 pubmed publisher
	Zhou X, Han T, Chen H, Baker P, Qi H, Zhang H. Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia. Exp Cell Res. 2017;359:195-204 pubmed publisher
	Nigdelioglu R, Hamanaka R, Meliton A, O LEARY E, Witt L, Cho T, et al. Transforming Growth Factor (TGF)-? Promotes de Novo Serine Synthesis for Collagen Production. J Biol Chem. 2016;291:27239-27251 pubmed publisher
	Jiao X, Li Y, Zhang T, Liu M, Chi Y. Role of Sirtuin3 in high glucose-induced apoptosis in renal tubular epithelial cells. Biochem Biophys Res Commun. 2016;480:387-393 pubmed publisher
	Yoon S, Kim J. Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity. Anat Cell Biol. 2016;49:165-176 pubmed

product information

CatalogNo :

10099-1-AP

AntigenName :

SIRT3

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

hSIRT3, SIR2 like protein 3, SIR2L3, SIRT3

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC001042

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

WB 1:1000 ;