This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Notch1
catalog :
10062-2-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Reference
Yin L, Wen X, Li M, Xu Y, Zhao X, Li J, et al. A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis. Oncol Lett. 2018;16:6283-6292 pubmed publisher
Du Y, Li D, Li N, Su C, Yang C, Lin C, et al. POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling. Cell Death Dis. 2018;9:995 pubmed publisher
Zhang H, Liu P, Jiang C, Jin X, Liu R, Li S, et al. Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury. PLoS ONE. 2018;13:e0193037 pubmed publisher
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, et al. Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition. Autophagy. 2018;14:404-418 pubmed publisher
Gong C, Li L, Qin C, Wu W, Liu Q, Li Y, et al. The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats. J Diabetes Res. 2017;2017:8968523 pubmed publisher
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, et al. Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling. Nat Commun. 2017;8:413 pubmed publisher
Yin Q, Wang W, Cui G, Yan L, Zhang S. Potential role of the Jagged1/Notch1 signaling pathway in the endothelial-myofibroblast transition during BLM-induced pulmonary fibrosis. J Cell Physiol. 2017;: pubmed publisher
Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, et al. Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation. J Exp Clin Cancer Res. 2017;36:10 pubmed publisher
Huang D, Wang S, Wang A, Chen X, Zhang H. Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation. Acta Biochim Biophys Sin (Shanghai). 2016;48:788-94 pubmed publisher
Nemeth Z, Csizmadia E, Vikstrom L, Li M, Bisht K, Feizi A, et al. Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth. Oncotarget. 2016;7:23919-32 pubmed publisher
Wang J, Lu R, Yang J, Li H, He Z, Jing N, et al. TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production. Nat Commun. 2015;6:8876 pubmed publisher
product information
CatalogNo :
10062-2-AP
AntigenName :
Notch1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
Notch gene homolog 1 (Drosophila)
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
mouse
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
9930111A19Rik, lin 12, Mis6, Notch1, Tan1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC138441
Category :
Cell Cycle;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:200 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.