Tyrosine Hydroxylase Antibody | ProSci XPS-2033 product information

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product summary

company name :

ProSci

product type :

antibody

product name :

Tyrosine Hydroxylase Antibody

catalog :

XPS-2033

quantity :

0.1 mL

price :

330 USD

clonality :

polyclonal

host :

sheep

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunohistochemistry, immunocytochemistry

product information

Catalog Number :

XPS-2033

Product Name :

Tyrosine Hydroxylase Antibody

Host Species :

Sheep

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.1 mL

List Price :

330 USD

CrossReactivity :

Human, Mouse, Rat, Dog, Bovine

Background :

Tyrosine Hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons.

ALTnames :

The, Tyrosine 3-hydroxylase, TH

Immunogen :

TH polyclonal antibody was raised against native rat tyrosine hydroxylase, purified from pheochromocytoma.

Purity :

Affinity Purified

Buffer :

100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.

Uses :

WB, IF, IHC

Application Summary :

Tyrosine Hydroxylase antibody is specific for the 60k rat TH in lysates of PC-12 Cells. Applications include Immunofluorescence (IF), Immunohistochemistry (IHC) and Western Blot (WB). The antibody has been characterized in blot immunolabeling and immunocytochemical studies and cross-reacts with many different mammalian and some non-mammalian forms of TH. When internally tested under ideal conditions the working dilutions were 1:1000 for IHC, IF and WB.

Storage :

For long term storage –80 C is recommended, but shorter term storage at –20 C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

General References :

Xu, Z.-Q., Lew, J. Y., Harada, K., Aman, K., Goldstein, M., Deutch, A., Haycock, J. W., and Hokfelt, T., "Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state-specific antibodies," Neuroscience, 82 (1998) 727-738.

General References :

Haycock, J.W. "Multiple forms of tyrosine hydroxylase in human neuroblastoma cells: Quantitation with isoform-specific antibodies," J. Neurochem. 60 (1993) 493-502.

General References :

Haycock, J.W., "Four forms of tyrosine hydroxylase are present in human adrenal medulla," J. Neurochem. 56 (1991) 2139 - 2142.

General References :

Haycock, J.W., "Quantitation of tyrosine hydroxylase protein levels: Spot immunolabeling with an affinity-purified antibody," Anal. Biochem. 181 (1989) 259 - 266.