HIV-1 p24 Antibody [7F4] | ProSci PM-6585 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProSci

product type :

antibody

product name :

HIV-1 p24 Antibody [7F4]

catalog :

PM-6585

quantity :

0.02 mg, 0.1 mg

price :

79, 315 USD

clonality :

polyclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7F4

The same clone is also sold as:

Rockland Immunochemicals: 200-301-BR6, 200-306-BR6, 200-303-BR6

reactivity :

Human immunodeficiency virus 1

application :

western blot, ELISA

product information

Catalog Number :

PM-6585

Product Name :

HIV-1 p24 Antibody [7F4]

Host Species :

Mouse

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.02 mg, 0.1 mg

List Price :

79, 315 USD

Clone :

7F4

Isotype :

IgG1

CrossReactivity :

Virus

Background :

HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2). The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3).

ALTnames :

HIV-1 p24 Antibody [7F4] :

Immunogen :

Mouse monoclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein.

Specificity :

By Western blot, anti-HIV-1 p24 antibody detects a ~24 kDa, a ~41 kDa, and a ~55 kDa protein, corresponding to HIV-1 p24 and to its precursors p41 and p55, respectively, in HIV-1 samples.

Purity :

HIV-1 p24 antibody is supplied as protein A purified IgG1.

Buffer :

HIV-1 p24 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration :

1 mg/mL

Uses :

E, WB

Application Summary :

PM-6585 can be used for detection of p24 by Western blot or ELISA at 0.2 – 0.5 g/mL.

Storage :

HIV-1 p24 Monoclonal Antibody can be stored at 4 C for three months and -20 C, stable for up to one year.

General References :

Goto T, Nakai M, and Ikuta K. The life-cycle of human immunodeficiency virus type 1. Micron 1998; 29:123-38.

General References :

Freed EO. HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 1998; 251:1-15.

General References :

Flynn BJ, Kastenmuller K, Wille-Reece U, et al. Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc. Natl. Acad. Sci. USA 2011; 108:7131–6.