Tau (phospho Ser262) Antibody | ProSci 79-152 product information

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product summary

company name :

ProSci

product type :

antibody

product name :

Tau (phospho Ser262) Antibody

catalog :

79-152

quantity :

0.1 mg

price :

315 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

product information

Catalog Number :

79-152

Product Name :

Tau (phospho Ser262) Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Antigen Modification :

Phospho-Specific

Product Type :

Primary Antibody

Size :

0.1 mg

List Price :

315 USD

CrossReactivity :

Human, Mouse, Rat

Background :

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

ALTnames :

TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, STK14A, MAPT, MTAPT, Neurofibrillary tangle protein, PHF-tau

Immunogen :

Tau (Phospho-Ser262) antibody was raised against a peptide sequence around phosphorylation site of serine 262 (I-G-S (p) -T-E) derived from Human Tau.

Specificity :

This antibody detects endogenous level of Tau only when phosphorylated at serine 262.

Purity :

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Buffer :

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration :

1 mg/mL

Uses :

WB, IHC, IF

Application Summary :

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Storage :

Store antibody at -20 C for up to one year.

General References :

Timm T, et al. (2003) EMBO J; 22 (19): 5090-5101.