ZIP14 Antibody | ProSci 6105 product information

product summary

company name :

ProSci

product type :

antibody

product name :

ZIP14 Antibody

catalog :

6105

quantity :

0.02 mg, 0.1 mg

price :

79, 315 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

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citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3	Xu X, Wang C, Zhu Y, Chen W, Shao S, Jiang F, et al. Decreased expression of SLC 39A14 is associated with tumor aggressiveness and biochemical recurrence of human prostate cancer. Onco Targets Ther. 2016;9:4197-205 pubmed publisher

product information

Catalog Number :

6105

Product Name :

ZIP14 Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.02 mg, 0.1 mg

List Price :

79, 315 USD

Isotype :

IgG

CrossReactivity :

Human, Mouse, Rat

Background :

ZIP14 Antibody: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

ALTnames :

ZIP14 Antibody: NET34, ZIP14, cig19, LZT-Hs4, KIAA0062, Zinc transporter ZIP14, LIV-1 subfamily of ZIP zinc transporter 4

Immunogen :

ZIP14 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP14.

Specificity :

At least three isoforms of ZIP14 are known to exist; this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.

Purity :

ZIP14 Antibody is affinity chromatography purified via peptide column.

Buffer :

ZIP14 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration :

1 mg/mL

Uses :

E, WB, IHC, IF

Application Summary :

ZIP14 antibody can be used for detection of ZIP14 by Western blot at 1 - 2 g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 g/mL. For immunofluorescence start at 20 g/mL.

Storage :

ZIP14 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

General References :

Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem. 2003; 278:50142-50.

General References :

Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch. 2004; 447:796-800.

General References :

Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta. 2003; 1611:16-30.

General References :

Taylor KM, Morgan HE, Johnson A, et al. Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14. FEBS Lett. 2005; 579:427-32.

more info or order :

ProSci product webpage