MIPU1 Antibody | ProSci 5219 product information

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product summary

company name :

ProSci

product type :

antibody

product name :

MIPU1 Antibody

catalog :

5219

quantity :

0.02 mg, 0.1 mg

price :

79, 315 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog Number :

5219

Product Name :

MIPU1 Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.02 mg, 0.1 mg

List Price :

79, 315 USD

Isotype :

IgG

CrossReactivity :

Human, Mouse, Rat

Background :

MIPU1 Antibody: Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.

ALTnames :

MIPU1 Antibody: MIPU1, Zinc finger protein 667

Immunogen :

MIPU1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human MIPU1.

Purity :

MIPU1 Antibody is affinity chromatography purified via peptide column.

Buffer :

MIPU1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration :

1 mg/mL

Uses :

E, WB, IHC, IF

Application Summary :

MIPU1 antibody can be used for detection of MIPU1 by Western blot at 1 g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 g/mL. For immunofluorescence start at 20 g/mL.

Storage :

MIPU1 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

General References :

Jiang L, Tang D, Wang K, et al. Functional analysis of a novel KRAB/C2H2 zinc finger protein Mipu1. Biochem. Biophys. Res. Commun.2007; 356:829-35.

General References :

Wang G, Zuo X, Jiang L, et al. Tissue expression and subcellular localization of Mipu1, a novel myocardial ischemia-related gene. Braz. J. Biol. Res.2009; epub.

General References :

Yuan C, Zhang HL, Liu Y, et al. Cloning and characterization of a new gene Mipu1 up-regulated during myocardial ischemia-reperfusion. Prog. Biochem. Biophys.2004; 31:231-6.

General References :

Wang G, Zuo X, Yuan C, et al. Mipu1, a novel rat zinc-finger protein, inhibits transcriptional activities of AP-1 and SRE in mitogen-activated protein kinase signaling pathway. Mol. Cell. Biochem.2009; 322:93-102.