ORAI3 Antibody | ProSci 49-890 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProSci

product type :

antibody

product name :

ORAI3 Antibody

catalog :

49-890

quantity :

0.05 mg

price :

350 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

49-890

Product Name :

ORAI3 Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.05 mg

List Price :

350 USD

CrossReactivity :

Human, Mouse, Rat

Background :

Recognizes human ORAI3, also known as Transmembrane protein 142C (TMEM142C), a 31.5 kDa multi-pass membrane protein belonging to the ORAI family. Antigen stimulation of immune cells triggers Ca2+ entry through Ca2+ release-activated Ca2+ (CRAC) channels. CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. ORAI3 is one of two mammalian homologs of ORAI1, a four- transmembrane spanning protein that is an essential component of CRAC channels. ORAI3, along with ORAI1 and ORAI2, functions as a Ca2+ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca2+ sensor. Studies indicate that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Is not expected to cross react with either ORAI1 or ORAI2.

ALTnames :

ORAI3, Protein orai-3, TMEM142C, Transmembrane protein 142C

Immunogen :

ORAI3 antibody was raised against a peptide near the N-Terminus of ORAI3 (Human).

Purity :

Affinity Chromatography

Buffer :

PBS, 0.02% sodium azide.

Uses :

WB, IHC

Application Summary :

ORAI3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 g/mL, immunofluorescence starting at 10 g/mL, and immunoprecipitation.

Storage :

Store ORAI3 antibody at 4 C or -20 C. As with all antibodies avoid freeze/thaw cycles. Store undiluted.