TGFB1 Antibody | ProSci 49-553 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProSci

product type :

antibody

product name :

TGFB1 Antibody

catalog :

49-553

quantity :

0.05 mg

price :

350 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog Number :

49-553

Product Name :

TGFB1 Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.05 mg

List Price :

350 USD

CrossReactivity :

Human

Background :

TGF- -1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF- isoforms (TGF- -1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF- -1, is a 25 kDa homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. TGF- -1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF- is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF- -1 sources include platelets, bone and soft tissues such as placenta and kidneys.

ALTnames :

TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB

Immunogen :

TGFB1 antibody was raised against Aa 286-293 (of 390) of full-length (including signal peptide) precursor TGFb protein.

Purity :

Immunoaffinity Chromatography

Buffer :

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

Uses :

E, WB, IHC, IF

Application Summary :

TGFB1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 g/mL.

Storage :

Store TGFB1 antibody at 4 C or -20 C. As with all antibodies avoid freeze/thaw cycles.