gp120 Antibody | ProSci 4777 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProSci

product type :

antibody

product name :

gp120 Antibody

catalog :

4777

quantity :

0.02 mg, 0.1 mg

price :

79, 315 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

Human immunodeficiency virus 1

application :

western blot, ELISA

product information

Catalog Number :

4777

Product Name :

gp120 Antibody

Host Species :

Goat

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.02 mg, 0.1 mg

List Price :

79, 315 USD

Isotype :

IgG

CrossReactivity :

Virus

Background :

gp120 Antibody: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

ALTnames :

gp120 Antibody: Envelope glycoprotein gp160

Immunogen :

gp120 antibody was raised against 15 amino acids from near the center of gp120.

Purity :

gp120 Antibody is affinity chromatography purified via peptide column.

Buffer :

gp120 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration :

1 mg/mL

Uses :

E, WB

Application Summary :

Gp120 antibody can be used for detection of gp120 by Western blot at 1 g/mL.

Storage :

gp120 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

General References :

Pinter A. Roles of HIV-1 Env variable regions in viral neutralization and vaccine development. Curr. HIV Res.2007; 5:542-53.

General References :

Alkhatib G and Berger EA. HIV coreceptors: from discovery and designation to new paradigms and promise. Eur. J. Med. Res.2007; 12:375-84.