CTRP5 Antibody | ProSci 3571 product information

product summary

company name :

ProSci

product type :

antibody

product name :

CTRP5 Antibody

catalog :

3571

quantity :

0.02 mg, 0.1 mg

price :

79, 315 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry

more info or order :

ProSci product webpage

citations: 1

Reference
Mandal M, Vasireddy V, Reddy G, Wang X, Moroi S, Pattnaik B, et al. CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion. Invest Ophthalmol Vis Sci. 2006;47:5505-13 pubmed

product information

Catalog Number :

3571

Product Name :

CTRP5 Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

0.02 mg, 0.1 mg

List Price :

79, 315 USD

Isotype :

IgG

CrossReactivity :

Human, Rat

Background :

CTRP5 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

ALTnames :

CTRP5 Antibody: CTRP5, CTRP5, UNQ303/PRO344, Complement C1q tumor necrosis factor-related protein 5

Immunogen :

CTRP5 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human CTRP5.

Specificity :

These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Purity :

CTRP5 Antibody is affinity chromatography purified via peptide column.

Buffer :

CTRP5 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration :

1 mg/mL

Uses :

E, WB, IHC

Application Summary :

CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 4 g/mL. Antibody can also be used for immunohistochemistry starting at 10 g/mL.

Storage :

CTRP5 antibody can be stored at 4 C for three months and -20 C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

General References :

Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.

General References :

Tsao T-S, Lodish HF, and Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Euro. J. Pharmacol. 2002; 440:213-21.

General References :

Wong GW, Wang J, Hug C, et al. A family of Acrp30/ adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.

General References :

Shapiro L and Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr. Biol. 1998; 8:335-8.

more info or order :

ProSci product webpage