Mouse Monoclonal Antibody to ESR1 | ProMab 31155 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ESR1

catalog :

31155

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A6F3

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

31155

Title :

Mouse Monoclonal Antibody to ESR1

Species :

Human;

Clone :

6A6F3;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.;

Immunogen :

Purified recombinant fragment of human ESR1 (AA: 2-185) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.Tumour Biol. 2015 Aug;36(8):6349-59. ; 2.Breast Cancer Res. 2014 Dec 12;16(6):494.;

Type :

Monoclonal Antibody

MW :

58.8kDa

Aliases :

MI; WS2; CMM8; WS2A; bHLHe32