Mouse Monoclonal Antibody to PLCG1 | ProMab 31122 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PLCG1

catalog :

31122

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F3D11

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

31122

Title :

Mouse Monoclonal Antibody to PLCG1

Species :

Human; Rat;

Clone :

2F3D11;

lsotype :

Mouse IgG2a

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.;

Immunogen :

Purified recombinant fragment of human PLCG1 (AA: 39-181) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400

References :

1.Cancer Discov. 2014 Apr;4(4):OF13. ; 2.Adv Biol Regul. 2013 Jan;53(1):51-62.;

Type :

Monoclonal Antibody

MW :

89.8kDa

Aliases :

Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95