Mouse Monoclonal Antibody to C3C | ProMab 31054 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to C3C

catalog :

31054

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8B5H2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

31054

Title :

Mouse Monoclonal Antibody to C3C

Species :

Human;

Clone :

8B5H2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.;

Immunogen :

Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:

References :

1.Blood. 2015 Apr 9;125(15):2359-69. ; 2.Mediators Inflamm. 2013;2013:716902.;

Type :

Monoclonal Antibody

MW :

187.1kDa

Aliases :

ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p