Mouse Monoclonal Antibody to BIN1 | ProMab 31050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BIN1

catalog :

31050

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B6A4

The same clone is also sold as:

Invitrogen: MA5-31651

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

31050

Title :

Mouse Monoclonal Antibody to BIN1

Species :

Human; Mouse;

Clone :

3B6A4;

lsotype :

Mouse IgG2b

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.;

Immunogen :

Purified recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400

References :

1.Trends Mol Med. 2013 Oct;19(10):594-603. ; 2.Mol Med. 2012 May 9;18:507-18. ;

Type :

Monoclonal Antibody

MW :

64.7kDa

Aliases :

AMPH2; AMPHL; SH3P9