Mouse Monoclonal Antibody to PTPN6 | ProMab 30938 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PTPN6

catalog :

30938

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E9E4

The same clone is also sold as:

Invitrogen: MA5-38614

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30938

Title :

Mouse Monoclonal Antibody to PTPN6

Species :

Human;

Clone :

2E9E4;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.;

Immunogen :

Purified recombinant fragment of human PTPN6 (AA: 243-541) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.Tumour Biol. 2014 May;35(5):4479-88. ; 2.Blood. 2011 Sep 29;118(13):3634-44. ;

Type :

Monoclonal Antibody

MW :

67.6kDa

Aliases :

HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1