Mouse Monoclonal Antibody to PDGFRB | ProMab 30853 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PDGFRB

catalog :

30853

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2G7B7

The same clone is also sold as:

Novus Biologicals: NBP2-52529

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30853

Title :

Mouse Monoclonal Antibody to PDGFRB

Species :

Human; Mouse;

Clone :

2G7B7;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.;

Immunogen :

Purified recombinant fragment of human PDGFRB (AA: 33-133) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400

References :

1.J Cell Sci. 2012 May 1;125(Pt 9):2276-87. ; 2.J Cell Physiol. 2012 May;227(5):2089-96.;

Type :

Monoclonal Antibody

MW :

124kDa

Aliases :

IMF1; IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1