antibody

Mouse Monoclonal Antibody to Rab8

30852

0.1 mg

monoclonal

mouse

nonconjugated

7G8B11

The same clone is also sold as:

• Novus Biologicals: NBP2-52548
• Invitrogen: MA5-31883

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

Mouse Monoclonal Antibody to Rab8

Human;

7G8B11;

Mouse IgG2b

0.1 mg

4℃; -20℃ for long term storage

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.;

Purified recombinant fragment of human Rab8 (AA: 68-207) expressed in E. Coli.

Purified antibody in PBS with 0.05% sodium azide

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400

1.Intervirology. 2008;51(3):182-8. ; 2.Mol Biol Cell. 2007 Jan;18(1):47-56. ;

Monoclonal Antibody

23.7kDa

MEL; RAB8A