Mouse Monoclonal Antibody to NOX4 | ProMab 30812 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to NOX4

catalog :

30812

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H2C4

The same clone is also sold as:

Invitrogen: MA5-38586

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30812

Title :

Mouse Monoclonal Antibody to NOX4

Species :

Human;

Clone :

3H2C4;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.;

Immunogen :

Purified recombinant fragment of human NOX4 (AA: 210-310) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.Stem Cells Dev. 2012 Aug 10;21(12):2212-21. ; 2.Cancer Biol Ther. 2010 Aug 1;10(3):223-31.;

Type :

Monoclonal Antibody

MW :

67kDa

Aliases :

KOX; KOX-1; RENOX