Mouse Monoclonal Antibody to TTR | ProMab 30784 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TTR

catalog :

30784

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E10C5

The same clone is also sold as:

Abnova: MAB16697
Invitrogen: MA1-221
Novus Biologicals: NBP2-52575
Abcam: ab204997

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30784

Title :

Mouse Monoclonal Antibody to TTR

Species :

Human;

Clone :

2E10C5;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009];

Immunogen :

Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

J Biol Chem. 2013 Nov 1;288(44):31752-60. ; Clin Exp Rheumatol. 2013 May-Jun;31(3):394-9.;

Type :

Monoclonal Antibody

MW :

15.9kDa

Aliases :

CTS; CTS1; PALB; TBPA; HEL111; HsT2651