Mouse Monoclonal Antibody to FGFR3 | ProMab 30777 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to FGFR3

catalog :

30777

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2H10B4

The same clone is also sold as:

Invitrogen: MA5-38521
Novus Biologicals: NBP2-52468
Abnova: MAB16690

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30777

Title :

Mouse Monoclonal Antibody to FGFR3

Species :

Human;

Clone :

2H10B4;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009];

Immunogen :

Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400

References :

Mol Cancer. 2013 Jul 31;12:83. ; Histochem Cell Biol. 2012 Nov;138(5):759-72.;

Type :

Monoclonal Antibody

MW :

87.7kDa

Aliases :

ACH; CEK2; JTK4; CD333; HSFGFR3EX