Mouse Monoclonal Antibody to MAP3K7 | ProMab 30765 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MAP3K7

catalog :

30765

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E8H4

The same clone is also sold as:

Invitrogen: MA5-38569

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30765

Title :

Mouse Monoclonal Antibody to MAP3K7

Species :

Human;

Clone :

3E8H4;

lsotype :

Mouse IgG2a

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.;

Immunogen :

Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM:

References :

Asian Pac J Cancer Prev. 2013;14(1):315-20. ; Blood. 2012 Jul 12;120(2):347-55.;

Type :

Monoclonal Antibody

MW :

67.2kDa

Aliases :

TAK1; MEKK7; TGF1a