Mouse Monoclonal Antibody to ERBB4 | ProMab 30755 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ERBB4

catalog :

30755

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G6B4

The same clone is also sold as:

Novus Biologicals: NBP2-52462

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30755

Title :

Mouse Monoclonal Antibody to ERBB4

Species :

Human;

Clone :

5G6B4;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.;

Immunogen :

Purified recombinant fragment of human ERBB4 (AA: 1159-1308) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400

References :

Neurosci Lett. 2012 Dec 7;531(2):209-14. ; EMBO Mol Med. 2013 Jul;5(7):1019-34. ;

Type :

Monoclonal Antibody

MW :

146.8kDa

Aliases :

HER4; ALS19; p180erbB4