Mouse Monoclonal Antibody to PDGFRA | ProMab 30728 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PDGFRA

catalog :

30728

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8E12F2

The same clone is also sold as:

Novus Biologicals: NBP2-52528
Invitrogen: MA5-38592

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30728

Title :

Mouse Monoclonal Antibody to PDGFRA

Species :

Human;

Clone :

8E12F2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Immunogen :

Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Stem Cells Dev. 2013 Jul 1;22(13):1932-43.; 2. Cancer Biol Ther. 2012 Dec;13(14):1384-9.

Type :

Monoclonal Antibody

MW :

122.7kDa

Aliases :

CD140A; PDGFR2; PDGFR-2; RHEPDGFRA