Mouse Monoclonal Antibody to CASP-7 | ProMab 30727 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CASP-7

catalog :

30727

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4D10B2

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30727

Title :

Mouse Monoclonal Antibody to CASP-7

Species :

Human;

Clone :

4D10B2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen :

Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Lung Cancer. 2009 Jul;65(1):19-24.; 2. Genes Cells. 2008 Jun;13(6):609-21.

Type :

Monoclonal Antibody

MW :

34.3kDa

Aliases :

MCH3; CMH-1; LICE2; CASP7; ICE-LAP3