Mouse Monoclonal Antibody to PIK3CG | ProMab 30687 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PIK3CG

catalog :

30687

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B5D2

The same clone is also sold as:

Invitrogen: MA5-38595

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30687

Title :

Mouse Monoclonal Antibody to PIK3CG

Species :

Human;

Clone :

4B5D2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Immunogen :

Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Lab Invest. 2013 May;93(5):566-76.; 2. Biochem Biophys Res Commun. 2011 Jan 28;404(4):968-73.

Type :

Monoclonal Antibody

MW :

126.5kDa

Aliases :

PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K